Centrioles: active players or passengers during mitosis?

Detalhes bibliográficos
Autor(a) principal: Debec, Alain
Data de Publicação: 2010
Outros Autores: Sullivan, William, Bettencourt-Dias, Monica
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.7/750
Resumo: There is no public supplementary material available.
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spelling Centrioles: active players or passengers during mitosis?AnimalsCell DivisionCell LineCentriolesCentrosomeCiliaDrosophilaMicrotubulesParthenogenesisSpindle ApparatusMitosisThere is no public supplementary material available.Centrioles are cylinders made of nine microtubule (MT) triplets present in many eukaryotes. Early studies, where centrosomes were seen at the poles of the mitotic spindle led to their coining as "the organ for cell division". However, a variety of subsequent observational and functional studies showed that centrosomes might not always be essential for mitosis. Here we review the arguments in this debate. We describe the centriole structure and its distribution in the eukaryotic tree of life and clarify its role in the organization of the centrosome and cilia, with an historical perspective. An important aspect of the debate addressed in this review is how centrioles are inherited and the role of the spindle in this process. In particular, germline inheritance of centrosomes, such as their de novo formation in parthenogenetic species, poses many interesting questions. We finish by discussing the most likely functions of centrioles and laying out new research avenues.There are no funders and sponsors indicated explicitly in the document.Springer VerlagARCADebec, AlainSullivan, WilliamBettencourt-Dias, Monica2017-05-04T16:28:29Z2010-03-192010-03-19T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.7/750engDebec, A., Sullivan, W. & Bettencourt-Dias, M. Cell. Mol. Life Sci. (2010) 67: 2173. doi:10.1007/s00018-010-0323-910.1007/s00018-010-0323-9info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-11-29T14:35:09Zoai:arca.igc.gulbenkian.pt:10400.7/750Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:58.744211Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Centrioles: active players or passengers during mitosis?
title Centrioles: active players or passengers during mitosis?
spellingShingle Centrioles: active players or passengers during mitosis?
Debec, Alain
Animals
Cell Division
Cell Line
Centrioles
Centrosome
Cilia
Drosophila
Microtubules
Parthenogenesis
Spindle Apparatus
Mitosis
title_short Centrioles: active players or passengers during mitosis?
title_full Centrioles: active players or passengers during mitosis?
title_fullStr Centrioles: active players or passengers during mitosis?
title_full_unstemmed Centrioles: active players or passengers during mitosis?
title_sort Centrioles: active players or passengers during mitosis?
author Debec, Alain
author_facet Debec, Alain
Sullivan, William
Bettencourt-Dias, Monica
author_role author
author2 Sullivan, William
Bettencourt-Dias, Monica
author2_role author
author
dc.contributor.none.fl_str_mv ARCA
dc.contributor.author.fl_str_mv Debec, Alain
Sullivan, William
Bettencourt-Dias, Monica
dc.subject.por.fl_str_mv Animals
Cell Division
Cell Line
Centrioles
Centrosome
Cilia
Drosophila
Microtubules
Parthenogenesis
Spindle Apparatus
Mitosis
topic Animals
Cell Division
Cell Line
Centrioles
Centrosome
Cilia
Drosophila
Microtubules
Parthenogenesis
Spindle Apparatus
Mitosis
description There is no public supplementary material available.
publishDate 2010
dc.date.none.fl_str_mv 2010-03-19
2010-03-19T00:00:00Z
2017-05-04T16:28:29Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.7/750
url http://hdl.handle.net/10400.7/750
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Debec, A., Sullivan, W. & Bettencourt-Dias, M. Cell. Mol. Life Sci. (2010) 67: 2173. doi:10.1007/s00018-010-0323-9
10.1007/s00018-010-0323-9
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer Verlag
publisher.none.fl_str_mv Springer Verlag
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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