Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal

Detalhes bibliográficos
Autor(a) principal: Dias, Mariana Carvalho
Data de Publicação: 2022
Outros Autores: dos Reis, Ricardo Soares, Santos, João Vasco, Nunes, Ana Paiva, Ferreira, Patricia, Maia, Bruno, Fragata, Isabel, Reis, Joao, Lopes, Joana Ramos, Cruz, Luis, Santo, Gustavo, Machado, Egidio, Gabriel, Denis, Felgueiras, Rui, Dória, Hugo Mota, Carneiro, Angelo, Correia, Manuel, Veloso, Luis Miguel, Barros, Pedro, Gregorio, Tiago, Carvalho, Andreia, Ribeiro, Manuel, Teotonio, Pedro, Neto, Lia, e Melo, Teresa Pinho, Canhao, Patricia, Filipe, João Pedro, Moreira, Goreti, Azevedo, Elsa, Silva, Maria Luis, Costa, Elisa Campos, Oliveira, Guilherme, Pereira, Liliana, Neves, Ligia, Rodrigues, Miguel, Marto, João Pedro, Calado, Sofia, Grenho, Fatima, Branco, Gabriel, Baptista, Tiago, Rocha, Jaime, Ferreira, Carla, Pinho, Joao, Amorim, José Manuel, Araujo, José Manuel, Neiva, Rui Manuel, Viana, João, Lobo, Mariana, Freitas, Alberto, Cruz, Vitor Tedim, Sargento-Freitas, João, Lopes, José Castro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031
Resumo: Introduction: Since the publication of endovascular treatment trials and European Stroke Guidelines, Portugal has re-organized stroke healthcare. The nine centers performing endovascular treatment are not equally distributed within the country, which may lead to differential access to endovascular treatment. Our main aim was to perform a descriptive analysis of the main treatment metrics regarding endovascular treatment in mainland Portugal and its administrative districts.Material and Methods: A retrospective national multicentric cohort study was conducted, including all ischemic stroke patients treated with endovascular treatment in mainland Portugal over two years (July 2015 to June 2017). All endovascular treatment centers contributed to an anonymized database. Demographic, stroke-related and procedure-related variables were collected. Crude endovascular treatment rates were calculated per 100 000 inhabitants for mainland Portugal, and each district and endovascular treatment standardized ratios (indirect age-sex standardization) were also calculated. Patient time metrics were computed as the median time between stroke onset, first-door, and puncture.Results: A total of 1625 endovascular treatment procedures were registered. The endovascular treatment rate was 8.27/100 000 inhabitants/year. We found regional heterogeneity in endovascular treatment rates (1.58 to 16.53/100 000/year), with higher rates in districts closer to endovascular treatment centers. When analyzed by district, the median time from stroke onset to puncture ranged from 212 to 432 minutes, reflecting regional heterogeneity.Conclusion: The overall national rate of EVT in the first two years after the organization of EVT-capable centers is one of the highest among European countries, however, significant regional disparities were documented. Moreover, stroke-onset-to-first-door times and in-hospital procedural times in the EVT centers were comparable to those reported in the randomized controlled trials performed in high-volume tertiary hospitals.
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spelling Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in PortugalAcesso a Tratamento Endovascular para Acidente Vascular Cerebral Isquémico em PortugalEndovascular ProceduresIschemic StrokeMechanical ThrombolysisPortugalThrombectomyAcidente Vascular Cerebral IsquémicoPortugalProcedimentos EndovascularesTrombólise MecânicaTrombectomiaIntroduction: Since the publication of endovascular treatment trials and European Stroke Guidelines, Portugal has re-organized stroke healthcare. The nine centers performing endovascular treatment are not equally distributed within the country, which may lead to differential access to endovascular treatment. Our main aim was to perform a descriptive analysis of the main treatment metrics regarding endovascular treatment in mainland Portugal and its administrative districts.Material and Methods: A retrospective national multicentric cohort study was conducted, including all ischemic stroke patients treated with endovascular treatment in mainland Portugal over two years (July 2015 to June 2017). All endovascular treatment centers contributed to an anonymized database. Demographic, stroke-related and procedure-related variables were collected. Crude endovascular treatment rates were calculated per 100 000 inhabitants for mainland Portugal, and each district and endovascular treatment standardized ratios (indirect age-sex standardization) were also calculated. Patient time metrics were computed as the median time between stroke onset, first-door, and puncture.Results: A total of 1625 endovascular treatment procedures were registered. The endovascular treatment rate was 8.27/100 000 inhabitants/year. We found regional heterogeneity in endovascular treatment rates (1.58 to 16.53/100 000/year), with higher rates in districts closer to endovascular treatment centers. When analyzed by district, the median time from stroke onset to puncture ranged from 212 to 432 minutes, reflecting regional heterogeneity.Conclusion: The overall national rate of EVT in the first two years after the organization of EVT-capable centers is one of the highest among European countries, however, significant regional disparities were documented. Moreover, stroke-onset-to-first-door times and in-hospital procedural times in the EVT centers were comparable to those reported in the randomized controlled trials performed in high-volume tertiary hospitals.Introdução: A aprovação do tratamento endovascular para o acidente vascular cerebral isquémico obrigou à reorganização dos cuidados de saúde em Portugal. Os nove centros que realizam tratamento endovascular não estão distribuídos equitativamente pelo território, o que poderá causar acesso diferencial a tratamento. O principal objetivo deste estudo é realizar uma análise descritiva da frequência e métricas temporais do tratamento endovascular em Portugal continental e seus distritos.Material e Métodos: Estudo de coorte nacional multicêntrico, incluindo todos os doentes com acidente vascular cerebral isquémico submetidos a tratamento endovascular em Portugal continental durante um período de dois anos (julho 2015 a junho 2017). Foram colhidos dados demográficos, relacionados com o acidente vascular cerebral e variáveis do procedimento. Taxas de tratamento endovascular brutas e ajustadas (ajuste indireto a idade e sexo) foram calculadas por 100 000 habitantes/ano para Portugal continental e cada distrito. Métricas de procedimento como tempo entre instalação, primeira porta e punção foram também analisadas.Resultados: Foram registados 1625 tratamentos endovasculares, indicando uma taxa bruta nacional de tratamento endovascular de 8,27/100 000 habitantes/ano. As taxas de tratamento endovascular entre distritos variaram entre 1,58 e 16,53/100 000/ano, com taxas mais elevadas nos distritos próximos a hospitais com tratamento endovascular. O tempo entre sintomas e punção femural entre distritos variou entre 212 e 432 minutos.Conclusão: Portugal continental apresenta uma taxa nacional de tratamento endovascular elevada, apresentando, contudo, assimetrias regionais no acesso. As métricas temporais foram comparáveis com as observadas nos ensaios clínicos piloto.Ordem dos Médicos2022-02-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031Acta Médica Portuguesa; Vol. 35 No. 2 (2022): February; 127-134Acta Médica Portuguesa; Vol. 35 N.º 2 (2022): Fevereiro; 127-1341646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031/6436https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031/6437https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031/6438Direitos de Autor (c) 2021 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessDias, Mariana Carvalhodos Reis, Ricardo SoaresSantos, João VascoNunes, Ana PaivaFerreira, PatriciaMaia, BrunoFragata, IsabelReis, JoaoLopes, Joana RamosCruz, LuisSanto, GustavoMachado, EgidioGabriel, DenisFelgueiras, RuiDória, Hugo MotaCarneiro, AngeloCorreia, ManuelVeloso, Luis MiguelBarros, PedroGregorio, TiagoCarvalho, AndreiaRibeiro, ManuelTeotonio, PedroNeto, Liae Melo, Teresa PinhoCanhao, PatriciaFilipe, João PedroMoreira, GoretiAzevedo, ElsaSilva, Maria LuisCosta, Elisa CamposOliveira, GuilhermePereira, LilianaNeves, LigiaRodrigues, MiguelMarto, João PedroCalado, SofiaGrenho, FatimaBranco, GabrielBaptista, TiagoRocha, JaimeFerreira, CarlaPinho, JoaoAmorim, José ManuelAraujo, José ManuelNeiva, Rui ManuelViana, JoãoLobo, MarianaFreitas, AlbertoCruz, Vitor TedimSargento-Freitas, JoãoLopes, José Castro2023-01-22T03:00:45Zoai:ojs.www.actamedicaportuguesa.com:article/15031Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:20:33.881823Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal
Acesso a Tratamento Endovascular para Acidente Vascular Cerebral Isquémico em Portugal
title Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal
spellingShingle Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal
Dias, Mariana Carvalho
Endovascular Procedures
Ischemic Stroke
Mechanical Thrombolysis
Portugal
Thrombectomy
Acidente Vascular Cerebral Isquémico
Portugal
Procedimentos Endovasculares
Trombólise Mecânica
Trombectomia
title_short Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal
title_full Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal
title_fullStr Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal
title_full_unstemmed Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal
title_sort Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal
author Dias, Mariana Carvalho
author_facet Dias, Mariana Carvalho
dos Reis, Ricardo Soares
Santos, João Vasco
Nunes, Ana Paiva
Ferreira, Patricia
Maia, Bruno
Fragata, Isabel
Reis, Joao
Lopes, Joana Ramos
Cruz, Luis
Santo, Gustavo
Machado, Egidio
Gabriel, Denis
Felgueiras, Rui
Dória, Hugo Mota
Carneiro, Angelo
Correia, Manuel
Veloso, Luis Miguel
Barros, Pedro
Gregorio, Tiago
Carvalho, Andreia
Ribeiro, Manuel
Teotonio, Pedro
Neto, Lia
e Melo, Teresa Pinho
Canhao, Patricia
Filipe, João Pedro
Moreira, Goreti
Azevedo, Elsa
Silva, Maria Luis
Costa, Elisa Campos
Oliveira, Guilherme
Pereira, Liliana
Neves, Ligia
Rodrigues, Miguel
Marto, João Pedro
Calado, Sofia
Grenho, Fatima
Branco, Gabriel
Baptista, Tiago
Rocha, Jaime
Ferreira, Carla
Pinho, Joao
Amorim, José Manuel
Araujo, José Manuel
Neiva, Rui Manuel
Viana, João
Lobo, Mariana
Freitas, Alberto
Cruz, Vitor Tedim
Sargento-Freitas, João
Lopes, José Castro
author_role author
author2 dos Reis, Ricardo Soares
Santos, João Vasco
Nunes, Ana Paiva
Ferreira, Patricia
Maia, Bruno
Fragata, Isabel
Reis, Joao
Lopes, Joana Ramos
Cruz, Luis
Santo, Gustavo
Machado, Egidio
Gabriel, Denis
Felgueiras, Rui
Dória, Hugo Mota
Carneiro, Angelo
Correia, Manuel
Veloso, Luis Miguel
Barros, Pedro
Gregorio, Tiago
Carvalho, Andreia
Ribeiro, Manuel
Teotonio, Pedro
Neto, Lia
e Melo, Teresa Pinho
Canhao, Patricia
Filipe, João Pedro
Moreira, Goreti
Azevedo, Elsa
Silva, Maria Luis
Costa, Elisa Campos
Oliveira, Guilherme
Pereira, Liliana
Neves, Ligia
Rodrigues, Miguel
Marto, João Pedro
Calado, Sofia
Grenho, Fatima
Branco, Gabriel
Baptista, Tiago
Rocha, Jaime
Ferreira, Carla
Pinho, Joao
Amorim, José Manuel
Araujo, José Manuel
Neiva, Rui Manuel
Viana, João
Lobo, Mariana
Freitas, Alberto
Cruz, Vitor Tedim
Sargento-Freitas, João
Lopes, José Castro
author2_role author
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author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
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dc.contributor.author.fl_str_mv Dias, Mariana Carvalho
dos Reis, Ricardo Soares
Santos, João Vasco
Nunes, Ana Paiva
Ferreira, Patricia
Maia, Bruno
Fragata, Isabel
Reis, Joao
Lopes, Joana Ramos
Cruz, Luis
Santo, Gustavo
Machado, Egidio
Gabriel, Denis
Felgueiras, Rui
Dória, Hugo Mota
Carneiro, Angelo
Correia, Manuel
Veloso, Luis Miguel
Barros, Pedro
Gregorio, Tiago
Carvalho, Andreia
Ribeiro, Manuel
Teotonio, Pedro
Neto, Lia
e Melo, Teresa Pinho
Canhao, Patricia
Filipe, João Pedro
Moreira, Goreti
Azevedo, Elsa
Silva, Maria Luis
Costa, Elisa Campos
Oliveira, Guilherme
Pereira, Liliana
Neves, Ligia
Rodrigues, Miguel
Marto, João Pedro
Calado, Sofia
Grenho, Fatima
Branco, Gabriel
Baptista, Tiago
Rocha, Jaime
Ferreira, Carla
Pinho, Joao
Amorim, José Manuel
Araujo, José Manuel
Neiva, Rui Manuel
Viana, João
Lobo, Mariana
Freitas, Alberto
Cruz, Vitor Tedim
Sargento-Freitas, João
Lopes, José Castro
dc.subject.por.fl_str_mv Endovascular Procedures
Ischemic Stroke
Mechanical Thrombolysis
Portugal
Thrombectomy
Acidente Vascular Cerebral Isquémico
Portugal
Procedimentos Endovasculares
Trombólise Mecânica
Trombectomia
topic Endovascular Procedures
Ischemic Stroke
Mechanical Thrombolysis
Portugal
Thrombectomy
Acidente Vascular Cerebral Isquémico
Portugal
Procedimentos Endovasculares
Trombólise Mecânica
Trombectomia
description Introduction: Since the publication of endovascular treatment trials and European Stroke Guidelines, Portugal has re-organized stroke healthcare. The nine centers performing endovascular treatment are not equally distributed within the country, which may lead to differential access to endovascular treatment. Our main aim was to perform a descriptive analysis of the main treatment metrics regarding endovascular treatment in mainland Portugal and its administrative districts.Material and Methods: A retrospective national multicentric cohort study was conducted, including all ischemic stroke patients treated with endovascular treatment in mainland Portugal over two years (July 2015 to June 2017). All endovascular treatment centers contributed to an anonymized database. Demographic, stroke-related and procedure-related variables were collected. Crude endovascular treatment rates were calculated per 100 000 inhabitants for mainland Portugal, and each district and endovascular treatment standardized ratios (indirect age-sex standardization) were also calculated. Patient time metrics were computed as the median time between stroke onset, first-door, and puncture.Results: A total of 1625 endovascular treatment procedures were registered. The endovascular treatment rate was 8.27/100 000 inhabitants/year. We found regional heterogeneity in endovascular treatment rates (1.58 to 16.53/100 000/year), with higher rates in districts closer to endovascular treatment centers. When analyzed by district, the median time from stroke onset to puncture ranged from 212 to 432 minutes, reflecting regional heterogeneity.Conclusion: The overall national rate of EVT in the first two years after the organization of EVT-capable centers is one of the highest among European countries, however, significant regional disparities were documented. Moreover, stroke-onset-to-first-door times and in-hospital procedural times in the EVT centers were comparable to those reported in the randomized controlled trials performed in high-volume tertiary hospitals.
publishDate 2022
dc.date.none.fl_str_mv 2022-02-01
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dc.rights.driver.fl_str_mv Direitos de Autor (c) 2021 Acta Médica Portuguesa
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rights_invalid_str_mv Direitos de Autor (c) 2021 Acta Médica Portuguesa
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 35 No. 2 (2022): February; 127-134
Acta Médica Portuguesa; Vol. 35 N.º 2 (2022): Fevereiro; 127-134
1646-0758
0870-399X
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