Diabetes hinders community-acquired pneumonia outcomes in hospitalized patients
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.18/4251 |
Resumo: | Objectives: This study aimed to estimate the prevalence of diabetes mellitus (DM) in hospitalized patients with community-acquired pneumonia (CAP) and its impact on hospital length of stay and inhospital mortality. Research design and methods: We carried out a retrospective, nationwide register analysis of CAP in adult patients admitted to Portuguese hospitals between 2009 and 2012. Anonymous data from 157 291 adult patients with CAP were extracted from the National Hospital Discharge Database and we performed a DM-conditioned analysis stratified by age, sex and year of hospitalization. Results: The 74 175 CAP episodes that matched the inclusion criteria showed a high burden of DM that tended to increase over time, from 23.7% in 2009 to 28.1% in 2012. Interestingly, patients with CAP had high DM prevalence in the context of the national DM prevalence. Episodes of CAP in patients with DM had on average 0.8 days longer hospital stay as compared to patients without DM ( p<0.0001), totaling a surplus of 15 370 days of stay attributable to DM in 19 212 admissions. In-hospital mortality was also significantly higher in patients with CAP who have DM (15.2%) versus those who have DM (13.5%) ( p=0.002). Conclusions: Our analysis revealed that DM prevalence was significantly increased within CAP hospital admissions, reinforcing other studies’ findings that suggest that DM is a risk factor for CAP. Since patients with CAP who have DM have longer hospitalization time and higher mortality rates, these results hold informative value for patient guidance and healthcare strategies. |
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Diabetes hinders community-acquired pneumonia outcomes in hospitalized patientsAdult DiabetesCommunity HealthRisk FactorsEstados de Saúde e de DoençaObjectives: This study aimed to estimate the prevalence of diabetes mellitus (DM) in hospitalized patients with community-acquired pneumonia (CAP) and its impact on hospital length of stay and inhospital mortality. Research design and methods: We carried out a retrospective, nationwide register analysis of CAP in adult patients admitted to Portuguese hospitals between 2009 and 2012. Anonymous data from 157 291 adult patients with CAP were extracted from the National Hospital Discharge Database and we performed a DM-conditioned analysis stratified by age, sex and year of hospitalization. Results: The 74 175 CAP episodes that matched the inclusion criteria showed a high burden of DM that tended to increase over time, from 23.7% in 2009 to 28.1% in 2012. Interestingly, patients with CAP had high DM prevalence in the context of the national DM prevalence. Episodes of CAP in patients with DM had on average 0.8 days longer hospital stay as compared to patients without DM ( p<0.0001), totaling a surplus of 15 370 days of stay attributable to DM in 19 212 admissions. In-hospital mortality was also significantly higher in patients with CAP who have DM (15.2%) versus those who have DM (13.5%) ( p=0.002). Conclusions: Our analysis revealed that DM prevalence was significantly increased within CAP hospital admissions, reinforcing other studies’ findings that suggest that DM is a risk factor for CAP. Since patients with CAP who have DM have longer hospitalization time and higher mortality rates, these results hold informative value for patient guidance and healthcare strategies.This work was supported by a Pfizer Grant to Ernesto Roma Foundation, Grant number FER2014/01 to MM.BMJ Publishing GroupRepositório Científico do Instituto Nacional de SaúdeMartins, M.Boavida, J.M.Raposo, J.F.Froes, F.Nunes, BaltazarRibeiro, R.T.Macedo, M.P.Penha-Gonçalves, C.2017-02-17T13:10:00Z2016-05-202016-05-20T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/4251engBMJ Open Diabetes Res Care. 2016 May 20;4(1):e000181. doi: 10.1136/bmjdrc-2015-000181. eCollection 20162052-489710.1136/bmjdrc-2015-000181info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:40:16ZPortal AgregadorONG |
dc.title.none.fl_str_mv |
Diabetes hinders community-acquired pneumonia outcomes in hospitalized patients |
title |
Diabetes hinders community-acquired pneumonia outcomes in hospitalized patients |
spellingShingle |
Diabetes hinders community-acquired pneumonia outcomes in hospitalized patients Martins, M. Adult Diabetes Community Health Risk Factors Estados de Saúde e de Doença |
title_short |
Diabetes hinders community-acquired pneumonia outcomes in hospitalized patients |
title_full |
Diabetes hinders community-acquired pneumonia outcomes in hospitalized patients |
title_fullStr |
Diabetes hinders community-acquired pneumonia outcomes in hospitalized patients |
title_full_unstemmed |
Diabetes hinders community-acquired pneumonia outcomes in hospitalized patients |
title_sort |
Diabetes hinders community-acquired pneumonia outcomes in hospitalized patients |
author |
Martins, M. |
author_facet |
Martins, M. Boavida, J.M. Raposo, J.F. Froes, F. Nunes, Baltazar Ribeiro, R.T. Macedo, M.P. Penha-Gonçalves, C. |
author_role |
author |
author2 |
Boavida, J.M. Raposo, J.F. Froes, F. Nunes, Baltazar Ribeiro, R.T. Macedo, M.P. Penha-Gonçalves, C. |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Nacional de Saúde |
dc.contributor.author.fl_str_mv |
Martins, M. Boavida, J.M. Raposo, J.F. Froes, F. Nunes, Baltazar Ribeiro, R.T. Macedo, M.P. Penha-Gonçalves, C. |
dc.subject.por.fl_str_mv |
Adult Diabetes Community Health Risk Factors Estados de Saúde e de Doença |
topic |
Adult Diabetes Community Health Risk Factors Estados de Saúde e de Doença |
description |
Objectives: This study aimed to estimate the prevalence of diabetes mellitus (DM) in hospitalized patients with community-acquired pneumonia (CAP) and its impact on hospital length of stay and inhospital mortality. Research design and methods: We carried out a retrospective, nationwide register analysis of CAP in adult patients admitted to Portuguese hospitals between 2009 and 2012. Anonymous data from 157 291 adult patients with CAP were extracted from the National Hospital Discharge Database and we performed a DM-conditioned analysis stratified by age, sex and year of hospitalization. Results: The 74 175 CAP episodes that matched the inclusion criteria showed a high burden of DM that tended to increase over time, from 23.7% in 2009 to 28.1% in 2012. Interestingly, patients with CAP had high DM prevalence in the context of the national DM prevalence. Episodes of CAP in patients with DM had on average 0.8 days longer hospital stay as compared to patients without DM ( p<0.0001), totaling a surplus of 15 370 days of stay attributable to DM in 19 212 admissions. In-hospital mortality was also significantly higher in patients with CAP who have DM (15.2%) versus those who have DM (13.5%) ( p=0.002). Conclusions: Our analysis revealed that DM prevalence was significantly increased within CAP hospital admissions, reinforcing other studies’ findings that suggest that DM is a risk factor for CAP. Since patients with CAP who have DM have longer hospitalization time and higher mortality rates, these results hold informative value for patient guidance and healthcare strategies. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-05-20 2016-05-20T00:00:00Z 2017-02-17T13:10:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.18/4251 |
url |
http://hdl.handle.net/10400.18/4251 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
BMJ Open Diabetes Res Care. 2016 May 20;4(1):e000181. doi: 10.1136/bmjdrc-2015-000181. eCollection 2016 2052-4897 10.1136/bmjdrc-2015-000181 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
BMJ Publishing Group |
publisher.none.fl_str_mv |
BMJ Publishing Group |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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