Distribution and expression of leptin in major salivary glands of a hyperleptinemia animal model

Detalhes bibliográficos
Autor(a) principal: Lucena, Sónia
Data de Publicação: 2016
Outros Autores: Capela e Silva, Fernando, Lamy, Elsa, Fialho, Luisa, Neves, Sandra
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10174/20609
Resumo: Saliva production is mainly regulated by the autonomic nervous system (sympathetic and parasympathetic); however studies indicate a possible hormonal influence on the control of salivary secretion. This study aims to assess if the induction of increased levels of circulating leptin influence the immunohistochemical expression of leptin at the level of major salivary glands in Wistar rats. It was found that the expression, in qualitative terms, of leptin has been positive, being more evident in submandibular and sublingual glands, either in the acini or ducts. However, through this technique, no obvious differences between groups could be observed. The results suggest that circulating leptin levels may not affect the expression of this hormone in the major salivary glands.
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spelling Distribution and expression of leptin in major salivary glands of a hyperleptinemia animal modelHyperleptinemialeptinsalivar glandsWistar ratsSaliva production is mainly regulated by the autonomic nervous system (sympathetic and parasympathetic); however studies indicate a possible hormonal influence on the control of salivary secretion. This study aims to assess if the induction of increased levels of circulating leptin influence the immunohistochemical expression of leptin at the level of major salivary glands in Wistar rats. It was found that the expression, in qualitative terms, of leptin has been positive, being more evident in submandibular and sublingual glands, either in the acini or ducts. However, through this technique, no obvious differences between groups could be observed. The results suggest that circulating leptin levels may not affect the expression of this hormone in the major salivary glands.Experimental Pathology and Health Sciences2017-02-06T10:27:34Z2017-02-062016-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10174/20609http://hdl.handle.net/10174/20609porslucena@uevora.ptfcs@uevora.ptecsl@uevora.ptndnd381Lucena, SóniaCapela e Silva, FernandoLamy, ElsaFialho, LuisaNeves, Sandrainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-03T19:10:23Zoai:dspace.uevora.pt:10174/20609Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:11:56.286430Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Distribution and expression of leptin in major salivary glands of a hyperleptinemia animal model
title Distribution and expression of leptin in major salivary glands of a hyperleptinemia animal model
spellingShingle Distribution and expression of leptin in major salivary glands of a hyperleptinemia animal model
Lucena, Sónia
Hyperleptinemia
leptin
salivar glands
Wistar rats
title_short Distribution and expression of leptin in major salivary glands of a hyperleptinemia animal model
title_full Distribution and expression of leptin in major salivary glands of a hyperleptinemia animal model
title_fullStr Distribution and expression of leptin in major salivary glands of a hyperleptinemia animal model
title_full_unstemmed Distribution and expression of leptin in major salivary glands of a hyperleptinemia animal model
title_sort Distribution and expression of leptin in major salivary glands of a hyperleptinemia animal model
author Lucena, Sónia
author_facet Lucena, Sónia
Capela e Silva, Fernando
Lamy, Elsa
Fialho, Luisa
Neves, Sandra
author_role author
author2 Capela e Silva, Fernando
Lamy, Elsa
Fialho, Luisa
Neves, Sandra
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Lucena, Sónia
Capela e Silva, Fernando
Lamy, Elsa
Fialho, Luisa
Neves, Sandra
dc.subject.por.fl_str_mv Hyperleptinemia
leptin
salivar glands
Wistar rats
topic Hyperleptinemia
leptin
salivar glands
Wistar rats
description Saliva production is mainly regulated by the autonomic nervous system (sympathetic and parasympathetic); however studies indicate a possible hormonal influence on the control of salivary secretion. This study aims to assess if the induction of increased levels of circulating leptin influence the immunohistochemical expression of leptin at the level of major salivary glands in Wistar rats. It was found that the expression, in qualitative terms, of leptin has been positive, being more evident in submandibular and sublingual glands, either in the acini or ducts. However, through this technique, no obvious differences between groups could be observed. The results suggest that circulating leptin levels may not affect the expression of this hormone in the major salivary glands.
publishDate 2016
dc.date.none.fl_str_mv 2016-01-01T00:00:00Z
2017-02-06T10:27:34Z
2017-02-06
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10174/20609
http://hdl.handle.net/10174/20609
url http://hdl.handle.net/10174/20609
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv slucena@uevora.pt
fcs@uevora.pt
ecsl@uevora.pt
nd
nd
381
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Experimental Pathology and Health Sciences
publisher.none.fl_str_mv Experimental Pathology and Health Sciences
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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