Prosthetic Mitral Valve Thrombosis in Pregnancy: From Thrombolysis to Anticoagulation
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.17/1994 |
Resumo: | INTRODUCTION: Pregnant women with mechanical prosthetic heart valves are at increased risk for valve thrombosis. Management decisions for this life-threatening complication are complex. Open-heart surgery has a very high risk of maternal mortality and fetal loss. Bleeding and embolic risks associated with thrombolytic agents, the limited efficacy of thrombolysis in certain subgroups, and a lack of experience in the setting of pregnancy raise important concerns. CASE REPORT: We report a case of mitral prosthetic valve thrombosis in early pregnancy, which was successfully treated with streptokinase. Ten years later, the same patient had an uneventful pregnancy, throughout which acenocoumarol was maintained. CONCLUSION: With this case we review the prevention (with oral anticoagulant therapy) and treatment of prosthetic valve thrombosis during pregnancy, which is important for both obstetrician and cardiologist. |
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Prosthetic Mitral Valve Thrombosis in Pregnancy: From Thrombolysis to AnticoagulationTrombose de Prótese Mitral na Gravidez: da Trombólise Até à AnticoagulaçãoHSM CARMAC GINAnticoagulants/therapeutic useMitral ValvePregnancy Complications, Cardiovascular/drug therapyPregnancyThrombolytic TherapyINTRODUCTION: Pregnant women with mechanical prosthetic heart valves are at increased risk for valve thrombosis. Management decisions for this life-threatening complication are complex. Open-heart surgery has a very high risk of maternal mortality and fetal loss. Bleeding and embolic risks associated with thrombolytic agents, the limited efficacy of thrombolysis in certain subgroups, and a lack of experience in the setting of pregnancy raise important concerns. CASE REPORT: We report a case of mitral prosthetic valve thrombosis in early pregnancy, which was successfully treated with streptokinase. Ten years later, the same patient had an uneventful pregnancy, throughout which acenocoumarol was maintained. CONCLUSION: With this case we review the prevention (with oral anticoagulant therapy) and treatment of prosthetic valve thrombosis during pregnancy, which is important for both obstetrician and cardiologist.Sociedade Portuguesa de CardiologiaRepositório do Centro Hospitalar Universitário de Lisboa Central, EPECardoso, GAguiar, CAndrade, MJPatrício, LFreire, ISerrano, FAnjos, RMendes, M2015-01-30T17:42:49Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/1994engRev Port Cardiol. 2015 Jan;34(1):71.e1-5.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:34:12Zoai:repositorio.chlc.min-saude.pt:10400.17/1994Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:19:22.139016Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Prosthetic Mitral Valve Thrombosis in Pregnancy: From Thrombolysis to Anticoagulation Trombose de Prótese Mitral na Gravidez: da Trombólise Até à Anticoagulação |
title |
Prosthetic Mitral Valve Thrombosis in Pregnancy: From Thrombolysis to Anticoagulation |
spellingShingle |
Prosthetic Mitral Valve Thrombosis in Pregnancy: From Thrombolysis to Anticoagulation Cardoso, G HSM CAR MAC GIN Anticoagulants/therapeutic use Mitral Valve Pregnancy Complications, Cardiovascular/drug therapy Pregnancy Thrombolytic Therapy |
title_short |
Prosthetic Mitral Valve Thrombosis in Pregnancy: From Thrombolysis to Anticoagulation |
title_full |
Prosthetic Mitral Valve Thrombosis in Pregnancy: From Thrombolysis to Anticoagulation |
title_fullStr |
Prosthetic Mitral Valve Thrombosis in Pregnancy: From Thrombolysis to Anticoagulation |
title_full_unstemmed |
Prosthetic Mitral Valve Thrombosis in Pregnancy: From Thrombolysis to Anticoagulation |
title_sort |
Prosthetic Mitral Valve Thrombosis in Pregnancy: From Thrombolysis to Anticoagulation |
author |
Cardoso, G |
author_facet |
Cardoso, G Aguiar, C Andrade, MJ Patrício, L Freire, I Serrano, F Anjos, R Mendes, M |
author_role |
author |
author2 |
Aguiar, C Andrade, MJ Patrício, L Freire, I Serrano, F Anjos, R Mendes, M |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE |
dc.contributor.author.fl_str_mv |
Cardoso, G Aguiar, C Andrade, MJ Patrício, L Freire, I Serrano, F Anjos, R Mendes, M |
dc.subject.por.fl_str_mv |
HSM CAR MAC GIN Anticoagulants/therapeutic use Mitral Valve Pregnancy Complications, Cardiovascular/drug therapy Pregnancy Thrombolytic Therapy |
topic |
HSM CAR MAC GIN Anticoagulants/therapeutic use Mitral Valve Pregnancy Complications, Cardiovascular/drug therapy Pregnancy Thrombolytic Therapy |
description |
INTRODUCTION: Pregnant women with mechanical prosthetic heart valves are at increased risk for valve thrombosis. Management decisions for this life-threatening complication are complex. Open-heart surgery has a very high risk of maternal mortality and fetal loss. Bleeding and embolic risks associated with thrombolytic agents, the limited efficacy of thrombolysis in certain subgroups, and a lack of experience in the setting of pregnancy raise important concerns. CASE REPORT: We report a case of mitral prosthetic valve thrombosis in early pregnancy, which was successfully treated with streptokinase. Ten years later, the same patient had an uneventful pregnancy, throughout which acenocoumarol was maintained. CONCLUSION: With this case we review the prevention (with oral anticoagulant therapy) and treatment of prosthetic valve thrombosis during pregnancy, which is important for both obstetrician and cardiologist. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-01-30T17:42:49Z 2015 2015-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.17/1994 |
url |
http://hdl.handle.net/10400.17/1994 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Rev Port Cardiol. 2015 Jan;34(1):71.e1-5. |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Cardiologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Cardiologia |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799131291357020160 |