A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compounds
Autor(a) principal: | |
---|---|
Data de Publicação: | 2012 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/7827 |
Resumo: | Despite the huge diversity of antibacterial compounds, bacterial resistance to first choice antibiotics has been drastically increasing. Moreover, the association between multi-resistant microorganisms and nosocomial infections highlight the problem, and the urgent need for solutions. Natural resources have been exploited in the last years and among them mushrooms could be an alternative as source of new antimicrobials. In this review we present an overview about the antimicrobial properties of mushroom extracts, highlight some of the active compounds identified including low and high molecular weight (LMW and HMW, respectively) compounds. LMW compounds are mainly secondary metabolites, such as sesquiterpenes and other terpenes, steroids, anthraquinones, benzoic acid derivatives, and quinolines, but also primary metabolites such as oxalic acid. HMW compounds are mainly peptides and proteins. Data available from literature indicate a higher antimicrobial activity of mushroom extracts against Gram-positive bacteria. Among all the mushrooms, Lentinus edodes is the most studied species and seems to have a broad antimicrobial action against both Gram-postive and Gram-negative bacteria. Plectasin peptide, obtained from Pseudoplectania nigrella, is the isolated compound with highest antimicrobial activity against Gram-positive bacteria, while 2-aminoquinoline, isolated from Leucopaxillus albissimus, presents the highest antimicrobial activity against Gram-negative bacteria. |
id |
RCAP_d7e940514a299c7dac2b7d87d838df59 |
---|---|
oai_identifier_str |
oai:bibliotecadigital.ipb.pt:10198/7827 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compoundsMushroomsBasidiomycetesAntimicrobialsGram positive bacteriaGram negative bacteriaDespite the huge diversity of antibacterial compounds, bacterial resistance to first choice antibiotics has been drastically increasing. Moreover, the association between multi-resistant microorganisms and nosocomial infections highlight the problem, and the urgent need for solutions. Natural resources have been exploited in the last years and among them mushrooms could be an alternative as source of new antimicrobials. In this review we present an overview about the antimicrobial properties of mushroom extracts, highlight some of the active compounds identified including low and high molecular weight (LMW and HMW, respectively) compounds. LMW compounds are mainly secondary metabolites, such as sesquiterpenes and other terpenes, steroids, anthraquinones, benzoic acid derivatives, and quinolines, but also primary metabolites such as oxalic acid. HMW compounds are mainly peptides and proteins. Data available from literature indicate a higher antimicrobial activity of mushroom extracts against Gram-positive bacteria. Among all the mushrooms, Lentinus edodes is the most studied species and seems to have a broad antimicrobial action against both Gram-postive and Gram-negative bacteria. Plectasin peptide, obtained from Pseudoplectania nigrella, is the isolated compound with highest antimicrobial activity against Gram-positive bacteria, while 2-aminoquinoline, isolated from Leucopaxillus albissimus, presents the highest antimicrobial activity against Gram-negative bacteria.ThiemeBiblioteca Digital do IPBAlves, Maria JoséFerreira, Isabel C.F.R.Dias, Joana F.Teixeira, VâniaMartins, AnabelaPintado, Manuela2013-01-07T09:48:55Z20122012-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfhttp://hdl.handle.net/10198/7827engAlves, Maria José; Ferreira, Isabel C.F.R.; Dias, Joana; Teixeira, Vânia; Martins, Anabela; Pintado, Manuela (2012). A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compounds. Planta Medica. ISSN 0032-0943. 78:16, p. 1707-17180032-094310.1055/s-0032-1315370info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:19:08Zoai:bibliotecadigital.ipb.pt:10198/7827Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:59:28.797366Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compounds |
title |
A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compounds |
spellingShingle |
A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compounds Alves, Maria José Mushrooms Basidiomycetes Antimicrobials Gram positive bacteria Gram negative bacteria |
title_short |
A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compounds |
title_full |
A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compounds |
title_fullStr |
A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compounds |
title_full_unstemmed |
A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compounds |
title_sort |
A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compounds |
author |
Alves, Maria José |
author_facet |
Alves, Maria José Ferreira, Isabel C.F.R. Dias, Joana F. Teixeira, Vânia Martins, Anabela Pintado, Manuela |
author_role |
author |
author2 |
Ferreira, Isabel C.F.R. Dias, Joana F. Teixeira, Vânia Martins, Anabela Pintado, Manuela |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Alves, Maria José Ferreira, Isabel C.F.R. Dias, Joana F. Teixeira, Vânia Martins, Anabela Pintado, Manuela |
dc.subject.por.fl_str_mv |
Mushrooms Basidiomycetes Antimicrobials Gram positive bacteria Gram negative bacteria |
topic |
Mushrooms Basidiomycetes Antimicrobials Gram positive bacteria Gram negative bacteria |
description |
Despite the huge diversity of antibacterial compounds, bacterial resistance to first choice antibiotics has been drastically increasing. Moreover, the association between multi-resistant microorganisms and nosocomial infections highlight the problem, and the urgent need for solutions. Natural resources have been exploited in the last years and among them mushrooms could be an alternative as source of new antimicrobials. In this review we present an overview about the antimicrobial properties of mushroom extracts, highlight some of the active compounds identified including low and high molecular weight (LMW and HMW, respectively) compounds. LMW compounds are mainly secondary metabolites, such as sesquiterpenes and other terpenes, steroids, anthraquinones, benzoic acid derivatives, and quinolines, but also primary metabolites such as oxalic acid. HMW compounds are mainly peptides and proteins. Data available from literature indicate a higher antimicrobial activity of mushroom extracts against Gram-positive bacteria. Among all the mushrooms, Lentinus edodes is the most studied species and seems to have a broad antimicrobial action against both Gram-postive and Gram-negative bacteria. Plectasin peptide, obtained from Pseudoplectania nigrella, is the isolated compound with highest antimicrobial activity against Gram-positive bacteria, while 2-aminoquinoline, isolated from Leucopaxillus albissimus, presents the highest antimicrobial activity against Gram-negative bacteria. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012 2012-01-01T00:00:00Z 2013-01-07T09:48:55Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/7827 |
url |
http://hdl.handle.net/10198/7827 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Alves, Maria José; Ferreira, Isabel C.F.R.; Dias, Joana; Teixeira, Vânia; Martins, Anabela; Pintado, Manuela (2012). A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compounds. Planta Medica. ISSN 0032-0943. 78:16, p. 1707-1718 0032-0943 10.1055/s-0032-1315370 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Thieme |
publisher.none.fl_str_mv |
Thieme |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799135218844565504 |