The effect of sodium fluorescein angiography on erythrocyte properties

Detalhes bibliográficos
Autor(a) principal: Sargento, L.
Data de Publicação: 1998
Outros Autores: Zabala, L., Saldanha, C., Souza-Ramalho, P., Martins e Silva, J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/17894
Resumo: © 1998 – IOS Press. All rights reserved
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spelling The effect of sodium fluorescein angiography on erythrocyte propertiesSodium fluorescein angiographyErythrocyte acetylcholinesteraseErythrocyte membrane fluidityErythrocyte aggregationDiabetes mellitus© 1998 – IOS Press. All rights reservedSodium fluorescein angiography is a widely used routine ophthalmological diagnostic procedure which enables the study of chorioretinal microcirculation and consists of the injection of sodium fluorescein into the systemic bloodstream. The aim of the present study was to evaluate whether or not fluorescein interferes with erythrocyte properties during the angiographic procedure. In a group of 37 patients, 26 with non-insulin-dependent diabetes mellitus (DM) with and without retinopathy, and 11 without diabetes mellitus (non-DM) although affected by other ophthalmological diseases, all undergoing routine angiography, blood samples were drawn before (T0) and 30 min (T30) after fluorescein injection. The erythrocyte aggregation index (EAI), membrane lipid fluidity and erythrocyte acetylcholinesterase activity were determined in both groups. After fluorescein injection there was no statistical change in EAI and erythrocyte membrane fluidity in either group. Erythrocyte acetylcholinesterase activity, a marker of membrane protein integrity, decreased significantly (p < 0:01) in the DM group. Membrane lipid fluidity did not change with fluorescein injection, however, (i) in the DM group erythrocyte membranes became more rigid than in the non-DM (DPH: p < 0:01); (ii) EAI and membrane lipid fluidity became significantly correlated (r = 0:6263, p < 0:05) in non-DM patients at T30. In conclusion, fluorescein administration for angiographic procedures seems to interact with erythrocyte membrane, namely, in diabetic patients, which may interfere with the blood flow in the microcirculation.IOS PressRepositório da Universidade de LisboaSargento, L.Zabala, L.Saldanha, C.Souza-Ramalho, P.Martins e Silva, J.2015-04-14T11:09:19Z19981998-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/17894engClinical Hemorheology and Microcirculation 18 (1998) 135–1391386-0291http://iospress.metapress.com/content/qufy5w9k8w6jag3l/?p=f879cbd7983743a58d2616a435500be1&pi=5info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-14T15:10:41ZPortal AgregadorONG
dc.title.none.fl_str_mv The effect of sodium fluorescein angiography on erythrocyte properties
title The effect of sodium fluorescein angiography on erythrocyte properties
spellingShingle The effect of sodium fluorescein angiography on erythrocyte properties
Sargento, L.
Sodium fluorescein angiography
Erythrocyte acetylcholinesterase
Erythrocyte membrane fluidity
Erythrocyte aggregation
Diabetes mellitus
title_short The effect of sodium fluorescein angiography on erythrocyte properties
title_full The effect of sodium fluorescein angiography on erythrocyte properties
title_fullStr The effect of sodium fluorescein angiography on erythrocyte properties
title_full_unstemmed The effect of sodium fluorescein angiography on erythrocyte properties
title_sort The effect of sodium fluorescein angiography on erythrocyte properties
author Sargento, L.
author_facet Sargento, L.
Zabala, L.
Saldanha, C.
Souza-Ramalho, P.
Martins e Silva, J.
author_role author
author2 Zabala, L.
Saldanha, C.
Souza-Ramalho, P.
Martins e Silva, J.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Sargento, L.
Zabala, L.
Saldanha, C.
Souza-Ramalho, P.
Martins e Silva, J.
dc.subject.por.fl_str_mv Sodium fluorescein angiography
Erythrocyte acetylcholinesterase
Erythrocyte membrane fluidity
Erythrocyte aggregation
Diabetes mellitus
topic Sodium fluorescein angiography
Erythrocyte acetylcholinesterase
Erythrocyte membrane fluidity
Erythrocyte aggregation
Diabetes mellitus
description © 1998 – IOS Press. All rights reserved
publishDate 1998
dc.date.none.fl_str_mv 1998
1998-01-01T00:00:00Z
2015-04-14T11:09:19Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/17894
url http://hdl.handle.net/10451/17894
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Clinical Hemorheology and Microcirculation 18 (1998) 135–139
1386-0291
http://iospress.metapress.com/content/qufy5w9k8w6jag3l/?p=f879cbd7983743a58d2616a435500be1&pi=5
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv IOS Press
publisher.none.fl_str_mv IOS Press
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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