Risk factors for renal scarring after first febrile urinary tract infection
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.25753/BirthGrowthMJ.v25.i1.8820 |
Resumo: | Introduction: The urinary tract infection (UTI) is one of the most common paediatric infectious diseases and it increases the risk for hypertension and end-stage renal disease. Authors’ aim was to identify risk factors for permanent renal injury after a first febrile urinary tract infection. Methods: Retrospective analysis of clinical, laboratorial and imaging data of children aged 1 to 36 months hospitalized between January 2010 and December 2012 with the first febrile UTI, comparing with late renal scintigraphy results. Results: Seventy seven children were included - 53% female, median age of 5 months, Escherichia coli identified in 95%. Renal scintigraphy, performed after the acute episode, revealed renal scars in 19.5%. Cystourethrography was done in 21 patients and vesicoureteral reflux identified in 3. There was no statistically difference between children with and without renal scarring regarding gender, age, body temperature, C-reactive protein, plasmatic creatinine level, bacteriuria or urine nitrite test, urine bacteria identified, presence of vesicoureteral reflux or recurrence rate of UTI. Conclusions: The authors did not detect any clinical, laboratory or imaging data that may predict progression to renal scarring following a first episode of febrile UTI in children between 1 and 36 months. |
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Risk factors for renal scarring after first febrile urinary tract infectionFatores de risco para cicatriz renal após a primeira infeção febril do trato urinárioOriginal ArticlesIntroduction: The urinary tract infection (UTI) is one of the most common paediatric infectious diseases and it increases the risk for hypertension and end-stage renal disease. Authors’ aim was to identify risk factors for permanent renal injury after a first febrile urinary tract infection. Methods: Retrospective analysis of clinical, laboratorial and imaging data of children aged 1 to 36 months hospitalized between January 2010 and December 2012 with the first febrile UTI, comparing with late renal scintigraphy results. Results: Seventy seven children were included - 53% female, median age of 5 months, Escherichia coli identified in 95%. Renal scintigraphy, performed after the acute episode, revealed renal scars in 19.5%. Cystourethrography was done in 21 patients and vesicoureteral reflux identified in 3. There was no statistically difference between children with and without renal scarring regarding gender, age, body temperature, C-reactive protein, plasmatic creatinine level, bacteriuria or urine nitrite test, urine bacteria identified, presence of vesicoureteral reflux or recurrence rate of UTI. Conclusions: The authors did not detect any clinical, laboratory or imaging data that may predict progression to renal scarring following a first episode of febrile UTI in children between 1 and 36 months.Introdução: A infeção do trato urinário (ITU) é uma das doenças infeciosas com maior incidência em Pediatria e apresenta risco de doença renal crónica e hipertensão arterial. O objetivo dos autores foi identificar os fatores de risco para lesão renal após o primeiro episódio de infeção do trato urinário febril. Métodos: Análise retrospetiva dos dados clínicos, laboratoriais e imagiológicos de crianças entre os 1 e 36 meses de idade, internados entre janeiro de 2010 e dezembro de 2012 por primeiro episódio de ITU febril, comparando os resultados finais da cintigrafia renal. Resultados: Foram incluídos 77 doentes, dos quais 53% eram do sexo feminino, com idade mediana de 5 meses e com identificação de Eschericia coli em 95%. A cintigrafia renal revelou cicatrizes renais em 19,5% da amostra. A cistouretrografia miccional seriada realizou-se em 21 crianças, tendo-se identificado refluxo vesicoureteral em 3 doentes. Comparando os casos com e sem cicatrizes renais, não se observaram diferenças estatisticamente significativas relativas a género, idade, temperatura corporal, doseamento sérico de proteína C reativa ou creatinina, bacteriúria ou nitritúria, tipo de bactéria identificada, presença de refluxo vesicoureteral ou taxa de recorrência das infeções do trato urinário. Conclusões: Os autores não detetaram nenhum fator de risco clínico, laboratorial ou imagiológico para progressão para lesão renal após um primeiro episódio de ITU febril em crianças entre 1 e 36 meses.Centro Hospitalar Universitário do Porto2016-03-16T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25753/BirthGrowthMJ.v25.i1.8820eng2183-9417Freitas, Ana CristinaLeite, JoanaMatos, PaulaRocha, LilianaCosta, TeresaFaria, Maria SameiroMota, Conceiçãoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-21T14:55:02Zoai:ojs.revistas.rcaap.pt:article/8820Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:56:10.697349Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Risk factors for renal scarring after first febrile urinary tract infection Fatores de risco para cicatriz renal após a primeira infeção febril do trato urinário |
title |
Risk factors for renal scarring after first febrile urinary tract infection |
spellingShingle |
Risk factors for renal scarring after first febrile urinary tract infection Freitas, Ana Cristina Original Articles |
title_short |
Risk factors for renal scarring after first febrile urinary tract infection |
title_full |
Risk factors for renal scarring after first febrile urinary tract infection |
title_fullStr |
Risk factors for renal scarring after first febrile urinary tract infection |
title_full_unstemmed |
Risk factors for renal scarring after first febrile urinary tract infection |
title_sort |
Risk factors for renal scarring after first febrile urinary tract infection |
author |
Freitas, Ana Cristina |
author_facet |
Freitas, Ana Cristina Leite, Joana Matos, Paula Rocha, Liliana Costa, Teresa Faria, Maria Sameiro Mota, Conceição |
author_role |
author |
author2 |
Leite, Joana Matos, Paula Rocha, Liliana Costa, Teresa Faria, Maria Sameiro Mota, Conceição |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Freitas, Ana Cristina Leite, Joana Matos, Paula Rocha, Liliana Costa, Teresa Faria, Maria Sameiro Mota, Conceição |
dc.subject.por.fl_str_mv |
Original Articles |
topic |
Original Articles |
description |
Introduction: The urinary tract infection (UTI) is one of the most common paediatric infectious diseases and it increases the risk for hypertension and end-stage renal disease. Authors’ aim was to identify risk factors for permanent renal injury after a first febrile urinary tract infection. Methods: Retrospective analysis of clinical, laboratorial and imaging data of children aged 1 to 36 months hospitalized between January 2010 and December 2012 with the first febrile UTI, comparing with late renal scintigraphy results. Results: Seventy seven children were included - 53% female, median age of 5 months, Escherichia coli identified in 95%. Renal scintigraphy, performed after the acute episode, revealed renal scars in 19.5%. Cystourethrography was done in 21 patients and vesicoureteral reflux identified in 3. There was no statistically difference between children with and without renal scarring regarding gender, age, body temperature, C-reactive protein, plasmatic creatinine level, bacteriuria or urine nitrite test, urine bacteria identified, presence of vesicoureteral reflux or recurrence rate of UTI. Conclusions: The authors did not detect any clinical, laboratory or imaging data that may predict progression to renal scarring following a first episode of febrile UTI in children between 1 and 36 months. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-03-16T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.25753/BirthGrowthMJ.v25.i1.8820 |
url |
https://doi.org/10.25753/BirthGrowthMJ.v25.i1.8820 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2183-9417 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Centro Hospitalar Universitário do Porto |
publisher.none.fl_str_mv |
Centro Hospitalar Universitário do Porto |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799130430327226368 |