Collagen membrane from bovine pericardium for treatment of long bone defect

Detalhes bibliográficos
Autor(a) principal: Yamanaka, J. S.
Data de Publicação: 2023
Outros Autores: Oliveira, A. C., Bastos, Ana Raquel Fernandes, Fernandes, Emanuel Mouta, Reis, R. L., Correlo, V. M., Shimano, A. C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/1822/81726
Resumo: First published: 17 August 2022
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spelling Collagen membrane from bovine pericardium for treatment of long bone defectbiomaterialBone repairCollagenpericardiumScience & TechnologyFirst published: 17 August 2022The treatment of bone regeneration failures has been constantly improved with the study of new biomaterials. Techgraft® is a collagen membrane derived from bovine pericardium, which has been shown to have biocompatibility and effectiveness in tissue repair. However, its use in orthopedics has not yet been evaluated. Therefore, the purpose of this study was to characterize a bovine pericardium collagen membrane and evaluate the effects of its use in the regeneration of a bone defect in rat tibia. Scanning electron microscopy, atomic force microscopy, weight lost and water uptake tests, and mechanical test were performed. Afterwards, the membrane was tested in an experimental study, using 12 male Sprague Dawley rats. A bone defect was surgically made in tibiae of animals, which were assigned to two groups (n = 6): bone defect treated with collagen membrane (TG) and bone defect without treatment (CONT). Then, tibiae were submitted to micro-CT. The membranes preserved their natural collagen characteristics, presenting great strength, high water absorption, hydrophilicity, and almost complete dissolution in 30 days. In the experimental study, the membrane enhanced the growth of bone tissue in contact with its surface. A higher bone volume and trabeculae number and less trabecular space was observed in bone defects of the membrane group compared to the control group at 21 days. In conclusion, the Techgraft membrane seems to have favorable characteristics for treatment of long bone repair.The authors gratefully acknowledge the financial support from the São Paulo Research Foundation (reference 2017/20051-0) and the scholarship from the Coordination for the Improvement of Higher Education Personnel.WileyUniversidade do MinhoYamanaka, J. S.Oliveira, A. C.Bastos, Ana Raquel FernandesFernandes, Emanuel MoutaReis, R. L.Correlo, V. M.Shimano, A. C.20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/81726engYamanaka JS, Oliveira AC, Bastos AR, et al. Collagen membrane from bovine pericardium for treatment of long bone defect. J Biomed Mater Res. 2023; 111(2): 261-270. doi:10.1002/jbm.b.351481552-49731552-498110.1002/jbm.b.35148https://onlinelibrary.wiley.com/doi/10.1002/jbm.b.35148info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-12-23T01:28:28Zoai:repositorium.sdum.uminho.pt:1822/81726Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:54:58.950761Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Collagen membrane from bovine pericardium for treatment of long bone defect
title Collagen membrane from bovine pericardium for treatment of long bone defect
spellingShingle Collagen membrane from bovine pericardium for treatment of long bone defect
Yamanaka, J. S.
biomaterial
Bone repair
Collagen
pericardium
Science & Technology
title_short Collagen membrane from bovine pericardium for treatment of long bone defect
title_full Collagen membrane from bovine pericardium for treatment of long bone defect
title_fullStr Collagen membrane from bovine pericardium for treatment of long bone defect
title_full_unstemmed Collagen membrane from bovine pericardium for treatment of long bone defect
title_sort Collagen membrane from bovine pericardium for treatment of long bone defect
author Yamanaka, J. S.
author_facet Yamanaka, J. S.
Oliveira, A. C.
Bastos, Ana Raquel Fernandes
Fernandes, Emanuel Mouta
Reis, R. L.
Correlo, V. M.
Shimano, A. C.
author_role author
author2 Oliveira, A. C.
Bastos, Ana Raquel Fernandes
Fernandes, Emanuel Mouta
Reis, R. L.
Correlo, V. M.
Shimano, A. C.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Yamanaka, J. S.
Oliveira, A. C.
Bastos, Ana Raquel Fernandes
Fernandes, Emanuel Mouta
Reis, R. L.
Correlo, V. M.
Shimano, A. C.
dc.subject.por.fl_str_mv biomaterial
Bone repair
Collagen
pericardium
Science & Technology
topic biomaterial
Bone repair
Collagen
pericardium
Science & Technology
description First published: 17 August 2022
publishDate 2023
dc.date.none.fl_str_mv 2023
2023-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/81726
url https://hdl.handle.net/1822/81726
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Yamanaka JS, Oliveira AC, Bastos AR, et al. Collagen membrane from bovine pericardium for treatment of long bone defect. J Biomed Mater Res. 2023; 111(2): 261-270. doi:10.1002/jbm.b.35148
1552-4973
1552-4981
10.1002/jbm.b.35148
https://onlinelibrary.wiley.com/doi/10.1002/jbm.b.35148
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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