Breast DWI at 3 T: influence of the fat-suppression technique on image quality and diagnostic performance
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.22/14209 |
Resumo: | Aim To evaluate two fat-suppression techniques: short tau inversion recovery (STIR) and spectral adiabatic inversion recovery (SPAIR) regarding image quality and diagnostic performance in diffusion-weighted imaging (DWI) of breast lesions at 3 T. Materials and methods Ninety-two women (mean age 48 ± 12.1 years; range 21–78 years) underwent breast MRI. Two DWI pulse sequences, with b-values (50 and 1000 s/mm2) were performed with STIR and SPAIR. The signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), suppression homogeneity, and apparent diffusion coefficient (ADC) values were quantitatively assessed for each technique. Values were compared between techniques and lesion type. Receiver operating characteristics (ROC) analysis was used to evaluate lesion discrimination. Results One hundred and fourteen lesions were analysed (40 benign and 74 malignant). SNR and CNR were significantly higher for DWI-SPAIR; fat-suppression uniformity was better for DWI-STIR (p < 1 × 10−4). ADC values for benign and malignant lesions and normal tissue were 1.92 × 10−3, 1.18 × 10−3, 1.86 × 10−3 s/mm2 for DWI-STIR and 1.80 × 10−3, 1.11 × 10−3, 1.79 × 10−3 s/mm2 for SPAIR, respectively. Comparison between fat-suppression techniques showed significant differences in mean ADC values for benign (p = 0.013) and malignant lesions (p = 0.001). DWI-STIR and -SPAIR ADC cut-offs were 1.42 × 10−3 and 1.46 × 10−3 s/mm2, respectively. Diagnostic performance for DWI-STIR versus SPAIR was: accuracy (81.6 versus 83.3%), area under curve (87.7 versus 89.2%), sensitivity (79.7 versus 85.1%), and specificity (85 versus 80%). Positive predictive value was similar. Conclusion The fat-saturation technique used in the present study may influence image quality and ADC quantification. Nevertheless, STIR and SPAIR techniques showed similar diagnostic performances, and therefore, both are suitable for use in clinical practice. |
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Breast DWI at 3 T: influence of the fat-suppression technique on image quality and diagnostic performanceBreastBreast NeoplasmsContrast MediaDiffusion Magnetic Resonance ImagingImage EnhancementImage Processing, Computer-AssistedROC CurveReproducibility of ResultsSensitivity and SpecificitySignal-To-Noise RatioAim To evaluate two fat-suppression techniques: short tau inversion recovery (STIR) and spectral adiabatic inversion recovery (SPAIR) regarding image quality and diagnostic performance in diffusion-weighted imaging (DWI) of breast lesions at 3 T. Materials and methods Ninety-two women (mean age 48 ± 12.1 years; range 21–78 years) underwent breast MRI. Two DWI pulse sequences, with b-values (50 and 1000 s/mm2) were performed with STIR and SPAIR. The signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), suppression homogeneity, and apparent diffusion coefficient (ADC) values were quantitatively assessed for each technique. Values were compared between techniques and lesion type. Receiver operating characteristics (ROC) analysis was used to evaluate lesion discrimination. Results One hundred and fourteen lesions were analysed (40 benign and 74 malignant). SNR and CNR were significantly higher for DWI-SPAIR; fat-suppression uniformity was better for DWI-STIR (p < 1 × 10−4). ADC values for benign and malignant lesions and normal tissue were 1.92 × 10−3, 1.18 × 10−3, 1.86 × 10−3 s/mm2 for DWI-STIR and 1.80 × 10−3, 1.11 × 10−3, 1.79 × 10−3 s/mm2 for SPAIR, respectively. Comparison between fat-suppression techniques showed significant differences in mean ADC values for benign (p = 0.013) and malignant lesions (p = 0.001). DWI-STIR and -SPAIR ADC cut-offs were 1.42 × 10−3 and 1.46 × 10−3 s/mm2, respectively. Diagnostic performance for DWI-STIR versus SPAIR was: accuracy (81.6 versus 83.3%), area under curve (87.7 versus 89.2%), sensitivity (79.7 versus 85.1%), and specificity (85 versus 80%). Positive predictive value was similar. Conclusion The fat-saturation technique used in the present study may influence image quality and ADC quantification. Nevertheless, STIR and SPAIR techniques showed similar diagnostic performances, and therefore, both are suitable for use in clinical practice.ElsevierRepositório Científico do Instituto Politécnico do PortoNogueira, LuisaBrandão, SofiaNunes, Rita G.Ferreira, Hugo AlexandreLoureiro, JoanaRamos, Isabel2019-07-01T16:16:50Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/14209eng10.1016/j.crad.2014.11.012info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-13T12:56:56Zoai:recipp.ipp.pt:10400.22/14209Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:34:02.145396Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Breast DWI at 3 T: influence of the fat-suppression technique on image quality and diagnostic performance |
title |
Breast DWI at 3 T: influence of the fat-suppression technique on image quality and diagnostic performance |
spellingShingle |
Breast DWI at 3 T: influence of the fat-suppression technique on image quality and diagnostic performance Nogueira, Luisa Breast Breast Neoplasms Contrast Media Diffusion Magnetic Resonance Imaging Image Enhancement Image Processing, Computer-Assisted ROC Curve Reproducibility of Results Sensitivity and Specificity Signal-To-Noise Ratio |
title_short |
Breast DWI at 3 T: influence of the fat-suppression technique on image quality and diagnostic performance |
title_full |
Breast DWI at 3 T: influence of the fat-suppression technique on image quality and diagnostic performance |
title_fullStr |
Breast DWI at 3 T: influence of the fat-suppression technique on image quality and diagnostic performance |
title_full_unstemmed |
Breast DWI at 3 T: influence of the fat-suppression technique on image quality and diagnostic performance |
title_sort |
Breast DWI at 3 T: influence of the fat-suppression technique on image quality and diagnostic performance |
author |
Nogueira, Luisa |
author_facet |
Nogueira, Luisa Brandão, Sofia Nunes, Rita G. Ferreira, Hugo Alexandre Loureiro, Joana Ramos, Isabel |
author_role |
author |
author2 |
Brandão, Sofia Nunes, Rita G. Ferreira, Hugo Alexandre Loureiro, Joana Ramos, Isabel |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Politécnico do Porto |
dc.contributor.author.fl_str_mv |
Nogueira, Luisa Brandão, Sofia Nunes, Rita G. Ferreira, Hugo Alexandre Loureiro, Joana Ramos, Isabel |
dc.subject.por.fl_str_mv |
Breast Breast Neoplasms Contrast Media Diffusion Magnetic Resonance Imaging Image Enhancement Image Processing, Computer-Assisted ROC Curve Reproducibility of Results Sensitivity and Specificity Signal-To-Noise Ratio |
topic |
Breast Breast Neoplasms Contrast Media Diffusion Magnetic Resonance Imaging Image Enhancement Image Processing, Computer-Assisted ROC Curve Reproducibility of Results Sensitivity and Specificity Signal-To-Noise Ratio |
description |
Aim To evaluate two fat-suppression techniques: short tau inversion recovery (STIR) and spectral adiabatic inversion recovery (SPAIR) regarding image quality and diagnostic performance in diffusion-weighted imaging (DWI) of breast lesions at 3 T. Materials and methods Ninety-two women (mean age 48 ± 12.1 years; range 21–78 years) underwent breast MRI. Two DWI pulse sequences, with b-values (50 and 1000 s/mm2) were performed with STIR and SPAIR. The signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), suppression homogeneity, and apparent diffusion coefficient (ADC) values were quantitatively assessed for each technique. Values were compared between techniques and lesion type. Receiver operating characteristics (ROC) analysis was used to evaluate lesion discrimination. Results One hundred and fourteen lesions were analysed (40 benign and 74 malignant). SNR and CNR were significantly higher for DWI-SPAIR; fat-suppression uniformity was better for DWI-STIR (p < 1 × 10−4). ADC values for benign and malignant lesions and normal tissue were 1.92 × 10−3, 1.18 × 10−3, 1.86 × 10−3 s/mm2 for DWI-STIR and 1.80 × 10−3, 1.11 × 10−3, 1.79 × 10−3 s/mm2 for SPAIR, respectively. Comparison between fat-suppression techniques showed significant differences in mean ADC values for benign (p = 0.013) and malignant lesions (p = 0.001). DWI-STIR and -SPAIR ADC cut-offs were 1.42 × 10−3 and 1.46 × 10−3 s/mm2, respectively. Diagnostic performance for DWI-STIR versus SPAIR was: accuracy (81.6 versus 83.3%), area under curve (87.7 versus 89.2%), sensitivity (79.7 versus 85.1%), and specificity (85 versus 80%). Positive predictive value was similar. Conclusion The fat-saturation technique used in the present study may influence image quality and ADC quantification. Nevertheless, STIR and SPAIR techniques showed similar diagnostic performances, and therefore, both are suitable for use in clinical practice. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015 2015-01-01T00:00:00Z 2019-07-01T16:16:50Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.22/14209 |
url |
http://hdl.handle.net/10400.22/14209 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.crad.2014.11.012 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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