Delayed sleep-wake phase disorder in a clinical population : gender and sub-population diferences

Detalhes bibliográficos
Autor(a) principal: Reis, Cátia
Data de Publicação: 2019
Outros Autores: Paiva, Maria Teresa Aguiar Dos Santos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/41369
Resumo: © 2020 All rights reserved.
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spelling Delayed sleep-wake phase disorder in a clinical population : gender and sub-population diferencesGender differencesPhase angleCircadian phaseCircadian misalignmentPhenotypes© 2020 All rights reserved.Objective/Background: Delayed sleep-wake phase disorder (DSWPD) is defined by a delay in the major sleep episode relative to desired or required sleep and wake times. The objectives of this study were to evaluate DSWPD in our population and to compare it with similar clinical data, to analyse gender differences, and to identify possible subpopulations based on circadian timing and alignment. Patients/Methods: 162 consecutive DSWPD patients from a sleep clinic with a median age of 35.5 (24.0) years, 85 (52.5%) males were studied. Patient data were obtained from a clinical interview composed of socio-demographic, life events, daily habits, consumptions, and comorbidities data; and from diaries, actimetry, melatonin and PSG T1. The Dim Light Melatonin Onset (DLMO) was used to define circadian alignment or misalignment. Results: In our DSWPD cohort, there were gender differences for different age groups (p=0.028). Men were more likely to be single and women more likely to be married (p=0.034). In students, school failure was higher for women (p<0.001); for workers, absenteeism was higher in women (p=0.001). In the circadian aligned (compared to misaligned group), DLMO was later (p<0.001), sleep onset time (p=0.046) was later, total sleep time (p=0.035), and number of sleep cycles (p=0.018) were lower, as measured using PSG T1. Conclusions: In this clinical population, DSWPD is more prevalent in young men and in middle age women, although with no overall significant differences between genders. There are two different phenotypes of DSWPD: circadian misaligned and circadian aligned. Depression is prevalent in both groups. Better definition, classification and diagnostic criteria for DSWPD are still needed, and targeted therapeutical intervention should be evaluated.This work was supported by Fundação para a Ciência e Tecnologia (FCT) PhD research grant PDE/BDE/114584/2016.Associação Brasileira de SonoRepositório da Universidade de LisboaReis, CátiaPaiva, Maria Teresa Aguiar Dos Santos2020-01-24T11:00:15Z20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/41369engSleep Sci. 2019;12(3):203-2131984-065910.5935/1984-0063.201900861984-0063info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:40:45Zoai:repositorio.ul.pt:10451/41369Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:54:38.547659Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Delayed sleep-wake phase disorder in a clinical population : gender and sub-population diferences
title Delayed sleep-wake phase disorder in a clinical population : gender and sub-population diferences
spellingShingle Delayed sleep-wake phase disorder in a clinical population : gender and sub-population diferences
Reis, Cátia
Gender differences
Phase angle
Circadian phase
Circadian misalignment
Phenotypes
title_short Delayed sleep-wake phase disorder in a clinical population : gender and sub-population diferences
title_full Delayed sleep-wake phase disorder in a clinical population : gender and sub-population diferences
title_fullStr Delayed sleep-wake phase disorder in a clinical population : gender and sub-population diferences
title_full_unstemmed Delayed sleep-wake phase disorder in a clinical population : gender and sub-population diferences
title_sort Delayed sleep-wake phase disorder in a clinical population : gender and sub-population diferences
author Reis, Cátia
author_facet Reis, Cátia
Paiva, Maria Teresa Aguiar Dos Santos
author_role author
author2 Paiva, Maria Teresa Aguiar Dos Santos
author2_role author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Reis, Cátia
Paiva, Maria Teresa Aguiar Dos Santos
dc.subject.por.fl_str_mv Gender differences
Phase angle
Circadian phase
Circadian misalignment
Phenotypes
topic Gender differences
Phase angle
Circadian phase
Circadian misalignment
Phenotypes
description © 2020 All rights reserved.
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-01-01T00:00:00Z
2020-01-24T11:00:15Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/41369
url http://hdl.handle.net/10451/41369
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Sleep Sci. 2019;12(3):203-213
1984-0659
10.5935/1984-0063.20190086
1984-0063
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Associação Brasileira de Sono
publisher.none.fl_str_mv Associação Brasileira de Sono
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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