EXOGENOUS PHOTOSENSITIVITY – Clinical Aspects and Responsible Agents

Detalhes bibliográficos
Autor(a) principal: Serra, David
Data de Publicação: 2011
Outros Autores: Santiago, Felicidade, Gonçalo, Margarida, Figueiredo, Américo
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.29021/spdv.69.2.603
Resumo: Phototoxic and photoallergic reactions consist of sun-induced skin reactions in the presence of photoactive chemicals, applied directly on the skin or of systemic use. They have several distinct clinical presentations, including photocontact urticaria, eczema on sun exposed areas sometimes with erythema multiforme, exaggerated sunburn, phytophotodermatitis, pseudoporphyria, photo-onycholysis, dyschromia and lupus erythematosus. Furthermore, there is mounting evidence that exposure to photoactive chemicals contributes to cutaneous carcinogenesis. Besides their clinical heterogeneity, there is also a great diversity of causative agents, with striking geographical and temporal variations. The authors review the spectrum of clinical patterns and also major photosensitizers, including UV- -filters of sunscreens and cosmetics, vegetal furocoumarins and drugs (NSAIDs, antimicrobials, phenothiazines, amiodarone, among others).
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spelling EXOGENOUS PHOTOSENSITIVITY – Clinical Aspects and Responsible AgentsFOTOSSENSIBILIDADE EXÓGENA – Aspectos Clínicos e Principais AgentesPhotosensitivityPhotoallergyPhototoxicityChromophoreUltraviolet radiationFotossensibilidadeFotoalergiaFototoxicidadeCromóforoRadiação ultravioletaPhototoxic and photoallergic reactions consist of sun-induced skin reactions in the presence of photoactive chemicals, applied directly on the skin or of systemic use. They have several distinct clinical presentations, including photocontact urticaria, eczema on sun exposed areas sometimes with erythema multiforme, exaggerated sunburn, phytophotodermatitis, pseudoporphyria, photo-onycholysis, dyschromia and lupus erythematosus. Furthermore, there is mounting evidence that exposure to photoactive chemicals contributes to cutaneous carcinogenesis. Besides their clinical heterogeneity, there is also a great diversity of causative agents, with striking geographical and temporal variations. The authors review the spectrum of clinical patterns and also major photosensitizers, including UV- -filters of sunscreens and cosmetics, vegetal furocoumarins and drugs (NSAIDs, antimicrobials, phenothiazines, amiodarone, among others).As reacções fototóxicas e fotoalérgicas são reacções cutâneas à exposição solar que ocorrem na presença de químicos fotoactivos. As apresentações clínicas são diversas e abrangem urticária de contacto fotoinduzida, eczema nas áreas fotoexpostas (por vezes com eritema multiforme), queimadura solar exagerada, fitofotodermatite, pseudoporfiria, foto-onicólise, discromia e lúpus eritematoso. Realça-se ainda o papel da exposição a químicos fotoactivos no desenvolvimento de neoplasias cutâneas. Do ponto de vista epidemiológico, verifica-se uma variação temporal e geográfica nos agentes responsáveis por estas reacções. Os autores propõem uma revisão dos mais comuns, incluindo os filtros UV, presentes em fotoprotectores e cosméticos, as furocumarinas de origem vegetal e alguns fármacos (anti-inflamatórios não esteróides, antimicrobianos, fenotiazinas, amiodarona, etc.).Sociedade Portuguesa de Dermatologia e Venereologia2011-06-23T00:00:00Zinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.69.2.603oai:ojs.revista.spdv.com.pt:article/603Journal of the Portuguese Society of Dermatology and Venereology; Vol 69 No 2 (2011): Abril / Junho; 171-188Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 69 n. 2 (2011): Abril / Junho; 171-1882182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/603https://doi.org/10.29021/spdv.69.2.603https://revista.spdv.com.pt/index.php/spdv/article/view/603/425Serra, DavidSantiago, FelicidadeGonçalo, MargaridaFigueiredo, Américoinfo:eu-repo/semantics/openAccess2022-10-06T12:34:58ZPortal AgregadorONG
dc.title.none.fl_str_mv EXOGENOUS PHOTOSENSITIVITY – Clinical Aspects and Responsible Agents
FOTOSSENSIBILIDADE EXÓGENA – Aspectos Clínicos e Principais Agentes
title EXOGENOUS PHOTOSENSITIVITY – Clinical Aspects and Responsible Agents
spellingShingle EXOGENOUS PHOTOSENSITIVITY – Clinical Aspects and Responsible Agents
Serra, David
Photosensitivity
Photoallergy
Phototoxicity
Chromophore
Ultraviolet radiation
Fotossensibilidade
Fotoalergia
Fototoxicidade
Cromóforo
Radiação ultravioleta
title_short EXOGENOUS PHOTOSENSITIVITY – Clinical Aspects and Responsible Agents
title_full EXOGENOUS PHOTOSENSITIVITY – Clinical Aspects and Responsible Agents
title_fullStr EXOGENOUS PHOTOSENSITIVITY – Clinical Aspects and Responsible Agents
title_full_unstemmed EXOGENOUS PHOTOSENSITIVITY – Clinical Aspects and Responsible Agents
title_sort EXOGENOUS PHOTOSENSITIVITY – Clinical Aspects and Responsible Agents
author Serra, David
author_facet Serra, David
Santiago, Felicidade
Gonçalo, Margarida
Figueiredo, Américo
author_role author
author2 Santiago, Felicidade
Gonçalo, Margarida
Figueiredo, Américo
author2_role author
author
author
dc.contributor.author.fl_str_mv Serra, David
Santiago, Felicidade
Gonçalo, Margarida
Figueiredo, Américo
dc.subject.por.fl_str_mv Photosensitivity
Photoallergy
Phototoxicity
Chromophore
Ultraviolet radiation
Fotossensibilidade
Fotoalergia
Fototoxicidade
Cromóforo
Radiação ultravioleta
topic Photosensitivity
Photoallergy
Phototoxicity
Chromophore
Ultraviolet radiation
Fotossensibilidade
Fotoalergia
Fototoxicidade
Cromóforo
Radiação ultravioleta
description Phototoxic and photoallergic reactions consist of sun-induced skin reactions in the presence of photoactive chemicals, applied directly on the skin or of systemic use. They have several distinct clinical presentations, including photocontact urticaria, eczema on sun exposed areas sometimes with erythema multiforme, exaggerated sunburn, phytophotodermatitis, pseudoporphyria, photo-onycholysis, dyschromia and lupus erythematosus. Furthermore, there is mounting evidence that exposure to photoactive chemicals contributes to cutaneous carcinogenesis. Besides their clinical heterogeneity, there is also a great diversity of causative agents, with striking geographical and temporal variations. The authors review the spectrum of clinical patterns and also major photosensitizers, including UV- -filters of sunscreens and cosmetics, vegetal furocoumarins and drugs (NSAIDs, antimicrobials, phenothiazines, amiodarone, among others).
publishDate 2011
dc.date.none.fl_str_mv 2011-06-23T00:00:00Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/other
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.29021/spdv.69.2.603
oai:ojs.revista.spdv.com.pt:article/603
url https://doi.org/10.29021/spdv.69.2.603
identifier_str_mv oai:ojs.revista.spdv.com.pt:article/603
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revista.spdv.com.pt/index.php/spdv/article/view/603
https://doi.org/10.29021/spdv.69.2.603
https://revista.spdv.com.pt/index.php/spdv/article/view/603/425
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
dc.source.none.fl_str_mv Journal of the Portuguese Society of Dermatology and Venereology; Vol 69 No 2 (2011): Abril / Junho; 171-188
Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 69 n. 2 (2011): Abril / Junho; 171-188
2182-2409
2182-2395
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.mail.fl_str_mv
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