Case of Flexural Exanthema as a Presenting Sign for COVID-19
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300069 |
Resumo: | ABSTRACT We report a case of a 84-year-old male hospitalized for bacterial pneumonia who, during hospitalization, developed a flexural exanthema in parallel with a positive swab for SARS-CoV-2. Supportive therapy was instituted, the rash disappeared in 7 days and the patient fully recovered. At the same time, two other cases of SARS-CoV-2 infection occurred in the same ward. Histopathology and immunohistochemistry of a skin biopsy showed a scarce predominantly perivascular lymphocytic infiltration in the upper dermis, predominantly by CD4+ T cells, a slight epidermotropism, spongiosis and focal parakeratosis, compatible with a viral exanthema or a maculopapular drug eruption. Patch testing with possible culprit drugs were negative. We seek to add value in understanding all the manifestations of SARS-CoV-2 infection and to draw attention to the importance of early identification of skin manifestations in association with COVID-19. |
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Case of Flexural Exanthema as a Presenting Sign for COVID-19Coronavirus InfectionsCOVID-19ExanthemaSARS-CoV-2.ABSTRACT We report a case of a 84-year-old male hospitalized for bacterial pneumonia who, during hospitalization, developed a flexural exanthema in parallel with a positive swab for SARS-CoV-2. Supportive therapy was instituted, the rash disappeared in 7 days and the patient fully recovered. At the same time, two other cases of SARS-CoV-2 infection occurred in the same ward. Histopathology and immunohistochemistry of a skin biopsy showed a scarce predominantly perivascular lymphocytic infiltration in the upper dermis, predominantly by CD4+ T cells, a slight epidermotropism, spongiosis and focal parakeratosis, compatible with a viral exanthema or a maculopapular drug eruption. Patch testing with possible culprit drugs were negative. We seek to add value in understanding all the manifestations of SARS-CoV-2 infection and to draw attention to the importance of early identification of skin manifestations in association with COVID-19.Sociedade Portuguesa de Dermatologia e Venereologia2020-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300069Revista da Sociedade Portuguesa de Dermatologia e Venereologia v.78 n.3 2020reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300069Oliveira,RaquelGonçalo,MargaridaFaria,CarlosDonaire,DavidBarbosa,BenildeCardoso,José CarlosJulião,Maria JoséMoura,JoséCarvalho,Armandoinfo:eu-repo/semantics/openAccess2024-02-06T17:26:27Zoai:scielo:S2182-23952020000300069Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:31:35.464538Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Case of Flexural Exanthema as a Presenting Sign for COVID-19 |
title |
Case of Flexural Exanthema as a Presenting Sign for COVID-19 |
spellingShingle |
Case of Flexural Exanthema as a Presenting Sign for COVID-19 Oliveira,Raquel Coronavirus Infections COVID-19 Exanthema SARS-CoV-2. |
title_short |
Case of Flexural Exanthema as a Presenting Sign for COVID-19 |
title_full |
Case of Flexural Exanthema as a Presenting Sign for COVID-19 |
title_fullStr |
Case of Flexural Exanthema as a Presenting Sign for COVID-19 |
title_full_unstemmed |
Case of Flexural Exanthema as a Presenting Sign for COVID-19 |
title_sort |
Case of Flexural Exanthema as a Presenting Sign for COVID-19 |
author |
Oliveira,Raquel |
author_facet |
Oliveira,Raquel Gonçalo,Margarida Faria,Carlos Donaire,David Barbosa,Benilde Cardoso,José Carlos Julião,Maria José Moura,José Carvalho,Armando |
author_role |
author |
author2 |
Gonçalo,Margarida Faria,Carlos Donaire,David Barbosa,Benilde Cardoso,José Carlos Julião,Maria José Moura,José Carvalho,Armando |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Oliveira,Raquel Gonçalo,Margarida Faria,Carlos Donaire,David Barbosa,Benilde Cardoso,José Carlos Julião,Maria José Moura,José Carvalho,Armando |
dc.subject.por.fl_str_mv |
Coronavirus Infections COVID-19 Exanthema SARS-CoV-2. |
topic |
Coronavirus Infections COVID-19 Exanthema SARS-CoV-2. |
description |
ABSTRACT We report a case of a 84-year-old male hospitalized for bacterial pneumonia who, during hospitalization, developed a flexural exanthema in parallel with a positive swab for SARS-CoV-2. Supportive therapy was instituted, the rash disappeared in 7 days and the patient fully recovered. At the same time, two other cases of SARS-CoV-2 infection occurred in the same ward. Histopathology and immunohistochemistry of a skin biopsy showed a scarce predominantly perivascular lymphocytic infiltration in the upper dermis, predominantly by CD4+ T cells, a slight epidermotropism, spongiosis and focal parakeratosis, compatible with a viral exanthema or a maculopapular drug eruption. Patch testing with possible culprit drugs were negative. We seek to add value in understanding all the manifestations of SARS-CoV-2 infection and to draw attention to the importance of early identification of skin manifestations in association with COVID-19. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-09-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300069 |
url |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300069 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300069 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
dc.source.none.fl_str_mv |
Revista da Sociedade Portuguesa de Dermatologia e Venereologia v.78 n.3 2020 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799137376928268288 |