Case of Flexural Exanthema as a Presenting Sign for COVID-19

Detalhes bibliográficos
Autor(a) principal: Oliveira,Raquel
Data de Publicação: 2020
Outros Autores: Gonçalo,Margarida, Faria,Carlos, Donaire,David, Barbosa,Benilde, Cardoso,José Carlos, Julião,Maria José, Moura,José, Carvalho,Armando
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300069
Resumo: ABSTRACT We report a case of a 84-year-old male hospitalized for bacterial pneumonia who, during hospitalization, developed a flexural exanthema in parallel with a positive swab for SARS-CoV-2. Supportive therapy was instituted, the rash disappeared in 7 days and the patient fully recovered. At the same time, two other cases of SARS-CoV-2 infection occurred in the same ward. Histopathology and immunohistochemistry of a skin biopsy showed a scarce predominantly perivascular lymphocytic infiltration in the upper dermis, predominantly by CD4+ T cells, a slight epidermotropism, spongiosis and focal parakeratosis, compatible with a viral exanthema or a maculopapular drug eruption. Patch testing with possible culprit drugs were negative. We seek to add value in understanding all the manifestations of SARS-CoV-2 infection and to draw attention to the importance of early identification of skin manifestations in association with COVID-19.
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spelling Case of Flexural Exanthema as a Presenting Sign for COVID-19Coronavirus InfectionsCOVID-19ExanthemaSARS-CoV-2.ABSTRACT We report a case of a 84-year-old male hospitalized for bacterial pneumonia who, during hospitalization, developed a flexural exanthema in parallel with a positive swab for SARS-CoV-2. Supportive therapy was instituted, the rash disappeared in 7 days and the patient fully recovered. At the same time, two other cases of SARS-CoV-2 infection occurred in the same ward. Histopathology and immunohistochemistry of a skin biopsy showed a scarce predominantly perivascular lymphocytic infiltration in the upper dermis, predominantly by CD4+ T cells, a slight epidermotropism, spongiosis and focal parakeratosis, compatible with a viral exanthema or a maculopapular drug eruption. Patch testing with possible culprit drugs were negative. We seek to add value in understanding all the manifestations of SARS-CoV-2 infection and to draw attention to the importance of early identification of skin manifestations in association with COVID-19.Sociedade Portuguesa de Dermatologia e Venereologia2020-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300069Revista da Sociedade Portuguesa de Dermatologia e Venereologia v.78 n.3 2020reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300069Oliveira,RaquelGonçalo,MargaridaFaria,CarlosDonaire,DavidBarbosa,BenildeCardoso,José CarlosJulião,Maria JoséMoura,JoséCarvalho,Armandoinfo:eu-repo/semantics/openAccess2024-02-06T17:26:27Zoai:scielo:S2182-23952020000300069Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:31:35.464538Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Case of Flexural Exanthema as a Presenting Sign for COVID-19
title Case of Flexural Exanthema as a Presenting Sign for COVID-19
spellingShingle Case of Flexural Exanthema as a Presenting Sign for COVID-19
Oliveira,Raquel
Coronavirus Infections
COVID-19
Exanthema
SARS-CoV-2.
title_short Case of Flexural Exanthema as a Presenting Sign for COVID-19
title_full Case of Flexural Exanthema as a Presenting Sign for COVID-19
title_fullStr Case of Flexural Exanthema as a Presenting Sign for COVID-19
title_full_unstemmed Case of Flexural Exanthema as a Presenting Sign for COVID-19
title_sort Case of Flexural Exanthema as a Presenting Sign for COVID-19
author Oliveira,Raquel
author_facet Oliveira,Raquel
Gonçalo,Margarida
Faria,Carlos
Donaire,David
Barbosa,Benilde
Cardoso,José Carlos
Julião,Maria José
Moura,José
Carvalho,Armando
author_role author
author2 Gonçalo,Margarida
Faria,Carlos
Donaire,David
Barbosa,Benilde
Cardoso,José Carlos
Julião,Maria José
Moura,José
Carvalho,Armando
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Oliveira,Raquel
Gonçalo,Margarida
Faria,Carlos
Donaire,David
Barbosa,Benilde
Cardoso,José Carlos
Julião,Maria José
Moura,José
Carvalho,Armando
dc.subject.por.fl_str_mv Coronavirus Infections
COVID-19
Exanthema
SARS-CoV-2.
topic Coronavirus Infections
COVID-19
Exanthema
SARS-CoV-2.
description ABSTRACT We report a case of a 84-year-old male hospitalized for bacterial pneumonia who, during hospitalization, developed a flexural exanthema in parallel with a positive swab for SARS-CoV-2. Supportive therapy was instituted, the rash disappeared in 7 days and the patient fully recovered. At the same time, two other cases of SARS-CoV-2 infection occurred in the same ward. Histopathology and immunohistochemistry of a skin biopsy showed a scarce predominantly perivascular lymphocytic infiltration in the upper dermis, predominantly by CD4+ T cells, a slight epidermotropism, spongiosis and focal parakeratosis, compatible with a viral exanthema or a maculopapular drug eruption. Patch testing with possible culprit drugs were negative. We seek to add value in understanding all the manifestations of SARS-CoV-2 infection and to draw attention to the importance of early identification of skin manifestations in association with COVID-19.
publishDate 2020
dc.date.none.fl_str_mv 2020-09-01
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dc.language.iso.fl_str_mv eng
language eng
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dc.publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
dc.source.none.fl_str_mv Revista da Sociedade Portuguesa de Dermatologia e Venereologia v.78 n.3 2020
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