Star-Shaped Gold Nanoparticles as Friendly Interfaces for Protein Electrochemistry: the Case Study of Cytochrome c

Detalhes bibliográficos
Autor(a) principal: Silveira, Célia M.
Data de Publicação: 2019
Outros Autores: Zumpano, Rosaceleste, Moreira, Miguel, de Almeida, Miguel Peixoto, Oliveira, Maria João, Bento, Marina, Montez, Cláudia, Paixão, Inês, Franco, Ricardo, Pereira, Eulália, Almeida, M. Gabriela
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/100120
Resumo: UID/QUI/50006/2019 POCI‐01‐0145‐FEDER‐007265 UID/Multi/04378/2019 POCI‐01‐0145‐FEDER‐007728 PTDC/NAN‐MAT/30589/2017 grant NORTE‐01‐0145‐FEDER‐000011 SFRH/BD/132057/2017
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network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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spelling Star-Shaped Gold Nanoparticles as Friendly Interfaces for Protein Electrochemistry: the Case Study of Cytochrome ccytochrome cdirect electron transfergold nanostarsnanoparticlesprotein electrochemistryCatalysisElectrochemistryUID/QUI/50006/2019 POCI‐01‐0145‐FEDER‐007265 UID/Multi/04378/2019 POCI‐01‐0145‐FEDER‐007728 PTDC/NAN‐MAT/30589/2017 grant NORTE‐01‐0145‐FEDER‐000011 SFRH/BD/132057/2017Gold nanostars with an average tip-to-tip length of 52±6 nm were functionalized with different capping agents and used as electrode modification materials for protein electrochemistry. Direct electron transfer between cytochrome c and nanostar-coated pyrolytic graphite electrodes was observed with the protein in solution. The electrochemical response was improved at nanostars functionalized with a 1 : 1 mixture of 11-mercaptoundecanoic acid and 4-mercaptobenzoic acid in comparison with gold nanospheres coated with a similar functionalization. Further immobilization of cytochrome c on pyrolytic graphite while conjugated with the same nanostars guaranteed the maintenance of the protein's native properties, whereas direct adsorption on the bare or nanostar-modified electrodes resulted in an altered conformational state. The pseudo-peroxidase activity of the altered cytochrome c was enhanced in the presence of the nanostars.UCIBIO - Applied Molecular Biosciences UnitCENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)DCM - Departamento de Ciência dos MateriaisUNINOVA-Instituto de Desenvolvimento de Novas TecnologiasRUNSilveira, Célia M.Zumpano, RosacelesteMoreira, Miguelde Almeida, Miguel PeixotoOliveira, Maria JoãoBento, MarinaMontez, CláudiaPaixão, InêsFranco, RicardoPereira, EuláliaAlmeida, M. Gabriela2022-03-09T01:31:27Z2019-09-022019-09-02T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article8application/pdfhttp://hdl.handle.net/10362/100120eng2196-0216PURE: 18059430https://doi.org/10.1002/celc.201901393info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:46:40Zoai:run.unl.pt:10362/100120Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:39:17.945721Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Star-Shaped Gold Nanoparticles as Friendly Interfaces for Protein Electrochemistry: the Case Study of Cytochrome c
title Star-Shaped Gold Nanoparticles as Friendly Interfaces for Protein Electrochemistry: the Case Study of Cytochrome c
spellingShingle Star-Shaped Gold Nanoparticles as Friendly Interfaces for Protein Electrochemistry: the Case Study of Cytochrome c
Silveira, Célia M.
cytochrome c
direct electron transfer
gold nanostars
nanoparticles
protein electrochemistry
Catalysis
Electrochemistry
title_short Star-Shaped Gold Nanoparticles as Friendly Interfaces for Protein Electrochemistry: the Case Study of Cytochrome c
title_full Star-Shaped Gold Nanoparticles as Friendly Interfaces for Protein Electrochemistry: the Case Study of Cytochrome c
title_fullStr Star-Shaped Gold Nanoparticles as Friendly Interfaces for Protein Electrochemistry: the Case Study of Cytochrome c
title_full_unstemmed Star-Shaped Gold Nanoparticles as Friendly Interfaces for Protein Electrochemistry: the Case Study of Cytochrome c
title_sort Star-Shaped Gold Nanoparticles as Friendly Interfaces for Protein Electrochemistry: the Case Study of Cytochrome c
author Silveira, Célia M.
author_facet Silveira, Célia M.
Zumpano, Rosaceleste
Moreira, Miguel
de Almeida, Miguel Peixoto
Oliveira, Maria João
Bento, Marina
Montez, Cláudia
Paixão, Inês
Franco, Ricardo
Pereira, Eulália
Almeida, M. Gabriela
author_role author
author2 Zumpano, Rosaceleste
Moreira, Miguel
de Almeida, Miguel Peixoto
Oliveira, Maria João
Bento, Marina
Montez, Cláudia
Paixão, Inês
Franco, Ricardo
Pereira, Eulália
Almeida, M. Gabriela
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv UCIBIO - Applied Molecular Biosciences Unit
CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)
DCM - Departamento de Ciência dos Materiais
UNINOVA-Instituto de Desenvolvimento de Novas Tecnologias
RUN
dc.contributor.author.fl_str_mv Silveira, Célia M.
Zumpano, Rosaceleste
Moreira, Miguel
de Almeida, Miguel Peixoto
Oliveira, Maria João
Bento, Marina
Montez, Cláudia
Paixão, Inês
Franco, Ricardo
Pereira, Eulália
Almeida, M. Gabriela
dc.subject.por.fl_str_mv cytochrome c
direct electron transfer
gold nanostars
nanoparticles
protein electrochemistry
Catalysis
Electrochemistry
topic cytochrome c
direct electron transfer
gold nanostars
nanoparticles
protein electrochemistry
Catalysis
Electrochemistry
description UID/QUI/50006/2019 POCI‐01‐0145‐FEDER‐007265 UID/Multi/04378/2019 POCI‐01‐0145‐FEDER‐007728 PTDC/NAN‐MAT/30589/2017 grant NORTE‐01‐0145‐FEDER‐000011 SFRH/BD/132057/2017
publishDate 2019
dc.date.none.fl_str_mv 2019-09-02
2019-09-02T00:00:00Z
2022-03-09T01:31:27Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/100120
url http://hdl.handle.net/10362/100120
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2196-0216
PURE: 18059430
https://doi.org/10.1002/celc.201901393
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 8
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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