QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/6271 |
Resumo: | Wild mushrooms have become attractive as a source of physiologically beneficial compounds including antioxidants such as phenolic compounds and tocopherols. The concentrations of antioxidant compounds (phenolics and α-tocopherol) and EC50 values of antioxidant activity (concentration required to achieve 50% of radical scavenging activity and lipid peroxidation inhibition, or 0.5 of absorbance in reducing power) were analyzed by partial least square (PLS) regression analysis. Three QCAR (Quantitative Composition-Activity Relationship) models were constructed and their robustness and predictability were verified by internal and external cross-validation methods. Antioxidant activity correlated well with phenolics and -tocopherol contents, the major antioxidants in wild mushrooms. The models proved to be useful tools in the prediction of mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition. |
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QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibitionWild mushroomsPhenolicsAlpha-tocopherolAntioxidant activityQCARPLSWild mushrooms have become attractive as a source of physiologically beneficial compounds including antioxidants such as phenolic compounds and tocopherols. The concentrations of antioxidant compounds (phenolics and α-tocopherol) and EC50 values of antioxidant activity (concentration required to achieve 50% of radical scavenging activity and lipid peroxidation inhibition, or 0.5 of absorbance in reducing power) were analyzed by partial least square (PLS) regression analysis. Three QCAR (Quantitative Composition-Activity Relationship) models were constructed and their robustness and predictability were verified by internal and external cross-validation methods. Antioxidant activity correlated well with phenolics and -tocopherol contents, the major antioxidants in wild mushrooms. The models proved to be useful tools in the prediction of mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition.ElsevierBiblioteca Digital do IPBFroufe, Hugo J.C.Abreu, Rui M.V.Ferreira, Isabel C.F.R.2011-11-04T11:48:30Z20112011-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfhttp://hdl.handle.net/10198/6271engFroufe, Hugo J.C.; Abreu, Rui M.V.; Ferreira, Isabel C.F.R. (2011). QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition. Chemometrics and Intelligent Laboratory Systems. ISSN 0169-7439. 109:2, p. 192-1960169-743910.1016/j.chemolab.2011.09.004info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-01-16T12:09:19ZPortal AgregadorONG |
dc.title.none.fl_str_mv |
QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition |
title |
QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition |
spellingShingle |
QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition Froufe, Hugo J.C. Wild mushrooms Phenolics Alpha-tocopherol Antioxidant activity QCAR PLS |
title_short |
QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition |
title_full |
QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition |
title_fullStr |
QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition |
title_full_unstemmed |
QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition |
title_sort |
QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition |
author |
Froufe, Hugo J.C. |
author_facet |
Froufe, Hugo J.C. Abreu, Rui M.V. Ferreira, Isabel C.F.R. |
author_role |
author |
author2 |
Abreu, Rui M.V. Ferreira, Isabel C.F.R. |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Froufe, Hugo J.C. Abreu, Rui M.V. Ferreira, Isabel C.F.R. |
dc.subject.por.fl_str_mv |
Wild mushrooms Phenolics Alpha-tocopherol Antioxidant activity QCAR PLS |
topic |
Wild mushrooms Phenolics Alpha-tocopherol Antioxidant activity QCAR PLS |
description |
Wild mushrooms have become attractive as a source of physiologically beneficial compounds including antioxidants such as phenolic compounds and tocopherols. The concentrations of antioxidant compounds (phenolics and α-tocopherol) and EC50 values of antioxidant activity (concentration required to achieve 50% of radical scavenging activity and lipid peroxidation inhibition, or 0.5 of absorbance in reducing power) were analyzed by partial least square (PLS) regression analysis. Three QCAR (Quantitative Composition-Activity Relationship) models were constructed and their robustness and predictability were verified by internal and external cross-validation methods. Antioxidant activity correlated well with phenolics and -tocopherol contents, the major antioxidants in wild mushrooms. The models proved to be useful tools in the prediction of mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-11-04T11:48:30Z 2011 2011-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/6271 |
url |
http://hdl.handle.net/10198/6271 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Froufe, Hugo J.C.; Abreu, Rui M.V.; Ferreira, Isabel C.F.R. (2011). QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition. Chemometrics and Intelligent Laboratory Systems. ISSN 0169-7439. 109:2, p. 192-196 0169-7439 10.1016/j.chemolab.2011.09.004 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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repository.mail.fl_str_mv |
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_version_ |
1777301838156005377 |