A throughput method using the quick easy cheap effective rugged safe method for the quantification of ibuprofen and its main metabolites in soils
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.22/9231 |
Resumo: | Quick, easy, cheap, effective, rugged, and safe extraction is a modern sample preparation method that involves a number of steps with a low susceptibility to error. The efficiency of a laboratory can be improved not only through labor reduction and consumable savings but also through the use of high-throughput methods and the reduction of wastes. In commercially available kits, different salts and buffers are mixed in anhydrous packages. The composition of these kits are optimized and fixed for particular applications by the suppliers. In this work three model compounds (ibuprofen and two of its main metabolites: hydroxyibuprofen and carboxyibuprofen) were chosen and the amount of each salt (magnesium sulfate, sodium chloride, sodium citrate, and disodium citrate sesquihydrate) in the quick, easy, cheap, effective, rugged, and safe content was optimized for three different soil samples (soils A, B, and C) with different organic carbon contents, using a 24 factorial design. The optimized extraction procedure was applied to 12 soil samples; ranging from river sediments to agricultural soils. Based on the analysis 100 samples, a price reduction of 5.1- (soil B), 5.7- (Soil C), and 6.1-fold (soil A) was achieved without compromising the performance of the method when compared to commercial kits. |
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A throughput method using the quick easy cheap effective rugged safe method for the quantification of ibuprofen and its main metabolites in soilsIbuprofenMetabolitesQuEChERSResponse surface methodologySoilQuick, easy, cheap, effective, rugged, and safe extraction is a modern sample preparation method that involves a number of steps with a low susceptibility to error. The efficiency of a laboratory can be improved not only through labor reduction and consumable savings but also through the use of high-throughput methods and the reduction of wastes. In commercially available kits, different salts and buffers are mixed in anhydrous packages. The composition of these kits are optimized and fixed for particular applications by the suppliers. In this work three model compounds (ibuprofen and two of its main metabolites: hydroxyibuprofen and carboxyibuprofen) were chosen and the amount of each salt (magnesium sulfate, sodium chloride, sodium citrate, and disodium citrate sesquihydrate) in the quick, easy, cheap, effective, rugged, and safe content was optimized for three different soil samples (soils A, B, and C) with different organic carbon contents, using a 24 factorial design. The optimized extraction procedure was applied to 12 soil samples; ranging from river sediments to agricultural soils. Based on the analysis 100 samples, a price reduction of 5.1- (soil B), 5.7- (Soil C), and 6.1-fold (soil A) was achieved without compromising the performance of the method when compared to commercial kits.Wiley-VCH VerlagRepositório Científico do Instituto Politécnico do PortoPaíga, PaulaDelerue-Matos, Cristina20162116-01-01T00:00:00Z2016-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/9231eng1615-931410.1002/jssc.201600412metadata only accessinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-13T12:50:31Zoai:recipp.ipp.pt:10400.22/9231Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:29:51.840157Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
A throughput method using the quick easy cheap effective rugged safe method for the quantification of ibuprofen and its main metabolites in soils |
title |
A throughput method using the quick easy cheap effective rugged safe method for the quantification of ibuprofen and its main metabolites in soils |
spellingShingle |
A throughput method using the quick easy cheap effective rugged safe method for the quantification of ibuprofen and its main metabolites in soils Paíga, Paula Ibuprofen Metabolites QuEChERS Response surface methodology Soil |
title_short |
A throughput method using the quick easy cheap effective rugged safe method for the quantification of ibuprofen and its main metabolites in soils |
title_full |
A throughput method using the quick easy cheap effective rugged safe method for the quantification of ibuprofen and its main metabolites in soils |
title_fullStr |
A throughput method using the quick easy cheap effective rugged safe method for the quantification of ibuprofen and its main metabolites in soils |
title_full_unstemmed |
A throughput method using the quick easy cheap effective rugged safe method for the quantification of ibuprofen and its main metabolites in soils |
title_sort |
A throughput method using the quick easy cheap effective rugged safe method for the quantification of ibuprofen and its main metabolites in soils |
author |
Paíga, Paula |
author_facet |
Paíga, Paula Delerue-Matos, Cristina |
author_role |
author |
author2 |
Delerue-Matos, Cristina |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Politécnico do Porto |
dc.contributor.author.fl_str_mv |
Paíga, Paula Delerue-Matos, Cristina |
dc.subject.por.fl_str_mv |
Ibuprofen Metabolites QuEChERS Response surface methodology Soil |
topic |
Ibuprofen Metabolites QuEChERS Response surface methodology Soil |
description |
Quick, easy, cheap, effective, rugged, and safe extraction is a modern sample preparation method that involves a number of steps with a low susceptibility to error. The efficiency of a laboratory can be improved not only through labor reduction and consumable savings but also through the use of high-throughput methods and the reduction of wastes. In commercially available kits, different salts and buffers are mixed in anhydrous packages. The composition of these kits are optimized and fixed for particular applications by the suppliers. In this work three model compounds (ibuprofen and two of its main metabolites: hydroxyibuprofen and carboxyibuprofen) were chosen and the amount of each salt (magnesium sulfate, sodium chloride, sodium citrate, and disodium citrate sesquihydrate) in the quick, easy, cheap, effective, rugged, and safe content was optimized for three different soil samples (soils A, B, and C) with different organic carbon contents, using a 24 factorial design. The optimized extraction procedure was applied to 12 soil samples; ranging from river sediments to agricultural soils. Based on the analysis 100 samples, a price reduction of 5.1- (soil B), 5.7- (Soil C), and 6.1-fold (soil A) was achieved without compromising the performance of the method when compared to commercial kits. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016 2016-01-01T00:00:00Z 2116-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.22/9231 |
url |
http://hdl.handle.net/10400.22/9231 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1615-9314 10.1002/jssc.201600412 |
dc.rights.driver.fl_str_mv |
metadata only access info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
metadata only access |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Wiley-VCH Verlag |
publisher.none.fl_str_mv |
Wiley-VCH Verlag |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799131394737176576 |