Computed tomography enterography or magnetic resonance enterography in Crohn's disease – which to choose?

Detalhes bibliográficos
Autor(a) principal: Azevedo, Aida
Data de Publicação: 2019
Outros Autores: Viana, Charlene, Costa, Ana Catarina, Martins, Sandra
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/67211
Resumo: Rationale and objectives: Evaluation of Crohn's disease by computed tomography enterography, magnetic resonance imaging enterography and colonoscopy is essential for disease monitoring. The aim of this study is to evaluate this exams acuity. Materials and methods: Patients with histological diagnosis of Crohn's disease who underwent computed tomography enterography, magnetic resonance imaging enterography and colonoscopy in the period of January 1st, 2009 and July 31st, 2016 and the realization of these exams did not exceed a time interval of 6 months was included. Sensitivity, specificity, positive and negative predictive values (PPV, NPV), Cohen's kappa (K), agreement and disagreement were calculated. Results: Comparing computed tomography enterography and magnetic resonance imaging enterography with colonoscopy, there was an agreement of 85.7% and a disagreement of 14.3% in Crohn's disease overall detection, for both exams. Computed tomography enterography and colonoscopy showed greater agreement in abscesses and lumen reduction detection (C = 95.2%) and magnetic resonance imaging enterography and colonoscopy in abscesses detection (C = 92.9%). Comparing magnetic resonance imaging enterography and computed tomography enterography, greater agreement was observed in detection of lumen reduction/dilatation (C = 96%). K showed considerable agreement in detection of mesenteric lymph nodes, fistulas, mural inflammation and thickening. The sensitivity, specificity, PPV and NPV were respectively set at 94.12% (95% CI 71.31-99.85), 50% (95% CI 6.76-93.24), 88.89% (95% CI 65.29-98.62) and 66.67% (95% CI 9.43-99.16) for CTE and 90.62% (95% CI 80.70-96.48), 33.33% (95% CI 4.33-77.72), 93.55% (95% CI 84.30-98.21) and 25% (95% CI 3.19-65.09) for MRIE. Conclusions: Although computed tomography enterography presents better sensitivity and specificity than magnetic resonance imaging enterography, both present high agreement values in detection of characteristic Crohn's disease findings, therefore the selection of the best test to monitor Crohn's disease should take into account aspects such as age, tolerability, disease phenotype and resources availability.
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spelling Computed tomography enterography or magnetic resonance enterography in Crohn's disease – which to choose?Enterografia por tomografia computadorizada ou por ressonância magnética na doença de Crohn - qual escolher?Crohn diseaseDiagnostic imagingComputed tomography enterographyMagnetic resonance imaging enterographyColonoscopyDoença de CrohnDiagnóstico por imagemEnterografia por ressonância magnéticaColonoscopiaCiências Médicas::Medicina BásicaRationale and objectives: Evaluation of Crohn's disease by computed tomography enterography, magnetic resonance imaging enterography and colonoscopy is essential for disease monitoring. The aim of this study is to evaluate this exams acuity. Materials and methods: Patients with histological diagnosis of Crohn's disease who underwent computed tomography enterography, magnetic resonance imaging enterography and colonoscopy in the period of January 1st, 2009 and July 31st, 2016 and the realization of these exams did not exceed a time interval of 6 months was included. Sensitivity, specificity, positive and negative predictive values (PPV, NPV), Cohen's kappa (K), agreement and disagreement were calculated. Results: Comparing computed tomography enterography and magnetic resonance imaging enterography with colonoscopy, there was an agreement of 85.7% and a disagreement of 14.3% in Crohn's disease overall detection, for both exams. Computed tomography enterography and colonoscopy showed greater agreement in abscesses and lumen reduction detection (C = 95.2%) and magnetic resonance imaging enterography and colonoscopy in abscesses detection (C = 92.9%). Comparing magnetic resonance imaging enterography and computed tomography enterography, greater agreement was observed in detection of lumen reduction/dilatation (C = 96%). K showed considerable agreement in detection of mesenteric lymph nodes, fistulas, mural inflammation and thickening. The sensitivity, specificity, PPV and NPV were respectively set at 94.12% (95% CI 71.31-99.85), 50% (95% CI 6.76-93.24), 88.89% (95% CI 65.29-98.62) and 66.67% (95% CI 9.43-99.16) for CTE and 90.62% (95% CI 80.70-96.48), 33.33% (95% CI 4.33-77.72), 93.55% (95% CI 84.30-98.21) and 25% (95% CI 3.19-65.09) for MRIE. Conclusions: Although computed tomography enterography presents better sensitivity and specificity than magnetic resonance imaging enterography, both present high agreement values in detection of characteristic Crohn's disease findings, therefore the selection of the best test to monitor Crohn's disease should take into account aspects such as age, tolerability, disease phenotype and resources availability.Fundamentação e objetivos: A avaliação da doença de Crohn por enterografia por tomografia computadorizada, enterografia por ressonância magnética e colonoscopia é essencial para o monitoramento da doença. Este estudo teve como objetivo avaliar a acuidade desses exames. Materiais e métodos: O estudo incluiu pacientes com diagnóstico histológico de doença de Crohn submetidos à enterografia por tomografia computadorizada, enterografia por ressonância magnética e colonoscopia no período entre 1° de janeiro de 2009 e 31 de julho de 2016; os exames foram realizados em um intervalo de máximo de seis meses. Calculou-se a sensibilidade, especificidade, valores preditivos positivo e negativo (VPP, VPN), Kappa (K) de Cohen, concordância e discordância. Resultados: Ao comparar enterografia por tomografia computadorizada e enterografia por ressonância magnética com colonoscopia, observou-se uma concordância de 85,7% e discordância de 14,3% na detecção global da doença de Crohn para ambos os exames. A enterografia por tomografia computadorizada e a colonoscopia mostraram maior concordância nos abscessos e na detecção da redução da luz (C = 95,2%) e enterografia por ressonância magnética e colonoscopia, na detecção de abscessos (C = 92,9%). Ao comparar a enterografia por ressonância magnética e a enterografia por tomografia computadorizada, observou-se maior concordância na detecção da redução/dilatação do lúmen (C = 96%). Os valores de K mostraram concordância considerável na detecção de linfonodos mesentéricos, fístulas, inflamação e espessamento mural. A sensibilidade, especificidade, VPP e VPN foram, respectivamente, 94,12% (IC 95%: 71,31 ± 99,85), 50% (IC 95%: 6,76 ± 93,24), 88,89% (IC 95%: 65,29 ± 98,62) e 66,67% (IC 95%: 9,43 ± 99,16) para ETC e 90,62% (IC 95%: 80,70 ± 96,48), 33,33% (IC 95%: 4,33 ± 77,72), 93,55% (IC 95%: 84,30 ± 98,21) e 25% (IC 95%: 3,19 ± 65,09) para enterografia por ressonância magnética. Conclusões: Embora a enterografia por tomografia computadorizada apresente melhor sensibilidade e especificidade que a enterografia por ressonância magnética, ambas apresentam altos valores de concordância na detecção dos achados característicos da doença de Crohn. Assim, a seleção do teste mais adequado para monitorar a doença de Crohn deve levar em consideração aspectos como idade, tolerabilidade, fenótipo da doença e disponibilidade de recursos.(undefined)ElsevierUniversidade do MinhoAzevedo, AidaViana, CharleneCosta, Ana CatarinaMartins, Sandra2019-012019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/67211engAzevedo, A., Viana, C., Costa, A. C., & Martins, S. F. (2019). Computed tomography enterography or magnetic resonance enterography in Crohn's disease-which to choose?. Journal of Coloproctology (Rio de Janeiro), 39(1), 9-142237-936310.1016/j.jcol.2018.09.003https://www.scielo.br/scielo.php?pid=S2237-93632019000100009&script=sci_arttextinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:23:11Zoai:repositorium.sdum.uminho.pt:1822/67211Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:16:51.223979Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Computed tomography enterography or magnetic resonance enterography in Crohn's disease – which to choose?
Enterografia por tomografia computadorizada ou por ressonância magnética na doença de Crohn - qual escolher?
title Computed tomography enterography or magnetic resonance enterography in Crohn's disease – which to choose?
spellingShingle Computed tomography enterography or magnetic resonance enterography in Crohn's disease – which to choose?
Azevedo, Aida
Crohn disease
Diagnostic imaging
Computed tomography enterography
Magnetic resonance imaging enterography
Colonoscopy
Doença de Crohn
Diagnóstico por imagem
Enterografia por ressonância magnética
Colonoscopia
Ciências Médicas::Medicina Básica
title_short Computed tomography enterography or magnetic resonance enterography in Crohn's disease – which to choose?
title_full Computed tomography enterography or magnetic resonance enterography in Crohn's disease – which to choose?
title_fullStr Computed tomography enterography or magnetic resonance enterography in Crohn's disease – which to choose?
title_full_unstemmed Computed tomography enterography or magnetic resonance enterography in Crohn's disease – which to choose?
title_sort Computed tomography enterography or magnetic resonance enterography in Crohn's disease – which to choose?
author Azevedo, Aida
author_facet Azevedo, Aida
Viana, Charlene
Costa, Ana Catarina
Martins, Sandra
author_role author
author2 Viana, Charlene
Costa, Ana Catarina
Martins, Sandra
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Azevedo, Aida
Viana, Charlene
Costa, Ana Catarina
Martins, Sandra
dc.subject.por.fl_str_mv Crohn disease
Diagnostic imaging
Computed tomography enterography
Magnetic resonance imaging enterography
Colonoscopy
Doença de Crohn
Diagnóstico por imagem
Enterografia por ressonância magnética
Colonoscopia
Ciências Médicas::Medicina Básica
topic Crohn disease
Diagnostic imaging
Computed tomography enterography
Magnetic resonance imaging enterography
Colonoscopy
Doença de Crohn
Diagnóstico por imagem
Enterografia por ressonância magnética
Colonoscopia
Ciências Médicas::Medicina Básica
description Rationale and objectives: Evaluation of Crohn's disease by computed tomography enterography, magnetic resonance imaging enterography and colonoscopy is essential for disease monitoring. The aim of this study is to evaluate this exams acuity. Materials and methods: Patients with histological diagnosis of Crohn's disease who underwent computed tomography enterography, magnetic resonance imaging enterography and colonoscopy in the period of January 1st, 2009 and July 31st, 2016 and the realization of these exams did not exceed a time interval of 6 months was included. Sensitivity, specificity, positive and negative predictive values (PPV, NPV), Cohen's kappa (K), agreement and disagreement were calculated. Results: Comparing computed tomography enterography and magnetic resonance imaging enterography with colonoscopy, there was an agreement of 85.7% and a disagreement of 14.3% in Crohn's disease overall detection, for both exams. Computed tomography enterography and colonoscopy showed greater agreement in abscesses and lumen reduction detection (C = 95.2%) and magnetic resonance imaging enterography and colonoscopy in abscesses detection (C = 92.9%). Comparing magnetic resonance imaging enterography and computed tomography enterography, greater agreement was observed in detection of lumen reduction/dilatation (C = 96%). K showed considerable agreement in detection of mesenteric lymph nodes, fistulas, mural inflammation and thickening. The sensitivity, specificity, PPV and NPV were respectively set at 94.12% (95% CI 71.31-99.85), 50% (95% CI 6.76-93.24), 88.89% (95% CI 65.29-98.62) and 66.67% (95% CI 9.43-99.16) for CTE and 90.62% (95% CI 80.70-96.48), 33.33% (95% CI 4.33-77.72), 93.55% (95% CI 84.30-98.21) and 25% (95% CI 3.19-65.09) for MRIE. Conclusions: Although computed tomography enterography presents better sensitivity and specificity than magnetic resonance imaging enterography, both present high agreement values in detection of characteristic Crohn's disease findings, therefore the selection of the best test to monitor Crohn's disease should take into account aspects such as age, tolerability, disease phenotype and resources availability.
publishDate 2019
dc.date.none.fl_str_mv 2019-01
2019-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/67211
url http://hdl.handle.net/1822/67211
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Azevedo, A., Viana, C., Costa, A. C., & Martins, S. F. (2019). Computed tomography enterography or magnetic resonance enterography in Crohn's disease-which to choose?. Journal of Coloproctology (Rio de Janeiro), 39(1), 9-14
2237-9363
10.1016/j.jcol.2018.09.003
https://www.scielo.br/scielo.php?pid=S2237-93632019000100009&script=sci_arttext
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dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
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instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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