Skin disorders in renal transplant recipients: a retrospective study

Detalhes bibliográficos
Autor(a) principal: Garrido, Pedro
Data de Publicação: 2017
Outros Autores: Borges-Costa, João
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/54381
Resumo: © 2017 by Anais Brasileiros de Dermatologia
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spelling Skin disorders in renal transplant recipients: a retrospective studyCarcinoma, basal cellCarcinoma, squamous cellKidney transplantationSkin neoplasms© 2017 by Anais Brasileiros de DermatologiaBackground: Immunosuppressive therapy, which is necessary to avoid graft rejection in renal transplant recipients, presents an increased risk of several pathologies, namely infectious and neoplastic. Objectives: To identify the most frequent skin diseases and their clinical and demographical risk factors within a population of renal transplant recipients. Methods: A retrospective study of renal transplant recipients referred to dermatology visit and observed for the first time from January 2008 to December 2014. Results: The study included 197 patients, 120 men (60,9%). Mean age was 50,7 years (±13,4). 12 patients (6,1%) had previous skin cancer. Infections were the most frequent reason of referral (93/197; 44%). From the total referred, 18,3% (36/197) presented pre-cancerous lesions. Malignancy was diagnosed in 36 patients (18,3%), with 29 non-melanoma skin cancers (14,7%) and 7 Kaposi sarcomas (3,6%). Ratio of basal cell carcinoma to squamous cell carcinoma was 1,1:1. Non-melanoma skin cancer was significantly associated with older age (p = 0,002), male gender (p = 0,028), history of previous skin cancer (p = 0,002) and higher duration of immunosuppressive therapy (p<0,001). Study limitations: Retrospective study, with data from the first visit in dermatology. We didn't made classification on skin-types. Conclusions: The great incidence of cutaneous infections and skin cancer is responsible for a significant morbidity. It is important to assure the regular dermatological follow-up of renal transplant recipients, which will promote the prevention, an early diagnosis and an efficient treatment.ElsevierRepositório da Universidade de LisboaGarrido, PedroBorges-Costa, João2022-09-08T13:38:07Z20172017-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/54381engAn Bras Dermatol. 2017;92(5):638-41.0365-059610.1590/abd1806-4841.201760401806-4841info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-14T15:40:46ZPortal AgregadorONG
dc.title.none.fl_str_mv Skin disorders in renal transplant recipients: a retrospective study
title Skin disorders in renal transplant recipients: a retrospective study
spellingShingle Skin disorders in renal transplant recipients: a retrospective study
Garrido, Pedro
Carcinoma, basal cell
Carcinoma, squamous cell
Kidney transplantation
Skin neoplasms
title_short Skin disorders in renal transplant recipients: a retrospective study
title_full Skin disorders in renal transplant recipients: a retrospective study
title_fullStr Skin disorders in renal transplant recipients: a retrospective study
title_full_unstemmed Skin disorders in renal transplant recipients: a retrospective study
title_sort Skin disorders in renal transplant recipients: a retrospective study
author Garrido, Pedro
author_facet Garrido, Pedro
Borges-Costa, João
author_role author
author2 Borges-Costa, João
author2_role author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Garrido, Pedro
Borges-Costa, João
dc.subject.por.fl_str_mv Carcinoma, basal cell
Carcinoma, squamous cell
Kidney transplantation
Skin neoplasms
topic Carcinoma, basal cell
Carcinoma, squamous cell
Kidney transplantation
Skin neoplasms
description © 2017 by Anais Brasileiros de Dermatologia
publishDate 2017
dc.date.none.fl_str_mv 2017
2017-01-01T00:00:00Z
2022-09-08T13:38:07Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/54381
url http://hdl.handle.net/10451/54381
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv An Bras Dermatol. 2017;92(5):638-41.
0365-0596
10.1590/abd1806-4841.20176040
1806-4841
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dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
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