Tuberculous Meningitis: The Important Role of Imaging
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.25754/pjp.2021.21668 |
Resumo: | Tuberculous meningitis is the most severe form of tuberculosis and the diagnosis continues to be challenging for clinicians. Indeed, many cases of Tuberculous meningitis cannot be confirmed based on clinical findings and laboratory techniques are largely insensitive or slow. Clinical presentation can be nonspecific and suggest alternative conditions. The difficulty in diagnosis often leads to a delay in treatment and subsequent mortality. We present a case of a four-year-old indian girl with meningitis that presented a clinical deterioration with neurological signs while under antibiotics. The epidemiological history and the neuroimaging findings of incipient hydrocephalus, infarcts and probable tuberculomas, were essential to evoke the diagnosis of Tuberculous meningitis. Diagnosis of Tuberculous meningitis is difficult as it can clinically present similarly to other forms of meningitis. The recognition of this entity involves a high index of suspicion based on the previous referred findings and is essential in terms of morbidity and mortality. |
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Tuberculous Meningitis: The Important Role of ImagingMeningite tuberculosa: a importância dos exames de imagemCase reportsTuberculous meningitis is the most severe form of tuberculosis and the diagnosis continues to be challenging for clinicians. Indeed, many cases of Tuberculous meningitis cannot be confirmed based on clinical findings and laboratory techniques are largely insensitive or slow. Clinical presentation can be nonspecific and suggest alternative conditions. The difficulty in diagnosis often leads to a delay in treatment and subsequent mortality. We present a case of a four-year-old indian girl with meningitis that presented a clinical deterioration with neurological signs while under antibiotics. The epidemiological history and the neuroimaging findings of incipient hydrocephalus, infarcts and probable tuberculomas, were essential to evoke the diagnosis of Tuberculous meningitis. Diagnosis of Tuberculous meningitis is difficult as it can clinically present similarly to other forms of meningitis. The recognition of this entity involves a high index of suspicion based on the previous referred findings and is essential in terms of morbidity and mortality.A meningite tuberculosa é a forma mais grave de tuberculose e o seu diagnóstico continua a ser um desafio. De facto, a maioria dos casos de meningite tuberculosa não podem ser diagnosticados com base nos achados clínicos e as técnicas laboratoriais são pouco sensíveis e morosas. A apresentação clínica pode ser inespecífica e sugerir outros diagnósticos. A dificuldade no diagnóstico frequentemente condiciona um atraso no tratamento e mortalidade subsequente. Apresentamos o caso de uma criança indiana de quatro anos com o diagnóstico de meningite que, sob antibioterapia, apresentou agravamento clínico com alterações neurológicas. A história epidemiológica e os achados de neuroimagem compatíveis com hidrocefalia incipiente, enfartes e prováveis tuberculomas foram essenciais para evocar o diagnóstico de meningite tuberculosa. O diagnóstico de meningite tuberculosa é difícil, pois pode apresentar-se clinicamente de forma semelhante a outras formas de meningite. O reconhecimento desta entidade envolve um elevado índice de suspeição com base nos achados anteriormente referidos e é essencial na prevenção de morbilidade e mortalidade associadas.Sociedade Portuguesa de Pediatria2021-11-03info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25754/pjp.2021.21668eng2184-44532184-3333Lemos, Ana PereiraConstante, Andreia DuarteConceição, CarlaVieira, José PedroBrito, Maria Joãoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T02:58:14Zoai:ojs.revistas.rcaap.pt:article/21668Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:25:37.000105Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Tuberculous Meningitis: The Important Role of Imaging Meningite tuberculosa: a importância dos exames de imagem |
title |
Tuberculous Meningitis: The Important Role of Imaging |
spellingShingle |
Tuberculous Meningitis: The Important Role of Imaging Lemos, Ana Pereira Case reports |
title_short |
Tuberculous Meningitis: The Important Role of Imaging |
title_full |
Tuberculous Meningitis: The Important Role of Imaging |
title_fullStr |
Tuberculous Meningitis: The Important Role of Imaging |
title_full_unstemmed |
Tuberculous Meningitis: The Important Role of Imaging |
title_sort |
Tuberculous Meningitis: The Important Role of Imaging |
author |
Lemos, Ana Pereira |
author_facet |
Lemos, Ana Pereira Constante, Andreia Duarte Conceição, Carla Vieira, José Pedro Brito, Maria João |
author_role |
author |
author2 |
Constante, Andreia Duarte Conceição, Carla Vieira, José Pedro Brito, Maria João |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Lemos, Ana Pereira Constante, Andreia Duarte Conceição, Carla Vieira, José Pedro Brito, Maria João |
dc.subject.por.fl_str_mv |
Case reports |
topic |
Case reports |
description |
Tuberculous meningitis is the most severe form of tuberculosis and the diagnosis continues to be challenging for clinicians. Indeed, many cases of Tuberculous meningitis cannot be confirmed based on clinical findings and laboratory techniques are largely insensitive or slow. Clinical presentation can be nonspecific and suggest alternative conditions. The difficulty in diagnosis often leads to a delay in treatment and subsequent mortality. We present a case of a four-year-old indian girl with meningitis that presented a clinical deterioration with neurological signs while under antibiotics. The epidemiological history and the neuroimaging findings of incipient hydrocephalus, infarcts and probable tuberculomas, were essential to evoke the diagnosis of Tuberculous meningitis. Diagnosis of Tuberculous meningitis is difficult as it can clinically present similarly to other forms of meningitis. The recognition of this entity involves a high index of suspicion based on the previous referred findings and is essential in terms of morbidity and mortality. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-11-03 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.25754/pjp.2021.21668 |
url |
https://doi.org/10.25754/pjp.2021.21668 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2184-4453 2184-3333 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Pediatria |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Pediatria |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799133524900446208 |