Tuberculous Meningitis: The Important Role of Imaging

Detalhes bibliográficos
Autor(a) principal: Lemos, Ana Pereira
Data de Publicação: 2021
Outros Autores: Constante, Andreia Duarte, Conceição, Carla, Vieira, José Pedro, Brito, Maria João
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25754/pjp.2021.21668
Resumo: Tuberculous meningitis is the most severe form of tuberculosis and the diagnosis continues to be challenging for clinicians. Indeed, many cases of Tuberculous meningitis cannot be confirmed based on clinical findings and laboratory techniques are largely insensitive or slow. Clinical presentation can be nonspecific and suggest alternative conditions. The difficulty in diagnosis often leads to a delay in treatment and subsequent mortality. We present a case of a four-year-old indian girl with meningitis that presented a clinical deterioration with neurological signs while under antibiotics. The epidemiological history and the neuroimaging findings of incipient hydrocephalus, infarcts and probable tuberculomas, were essential to evoke the diagnosis of Tuberculous meningitis. Diagnosis of Tuberculous meningitis is difficult as it can clinically present similarly to other forms of meningitis. The recognition of this entity involves a high index of suspicion based on the previous referred findings and is essential in terms of morbidity and mortality.
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spelling Tuberculous Meningitis: The Important Role of ImagingMeningite tuberculosa: a importância dos exames de imagemCase reportsTuberculous meningitis is the most severe form of tuberculosis and the diagnosis continues to be challenging for clinicians. Indeed, many cases of Tuberculous meningitis cannot be confirmed based on clinical findings and laboratory techniques are largely insensitive or slow. Clinical presentation can be nonspecific and suggest alternative conditions. The difficulty in diagnosis often leads to a delay in treatment and subsequent mortality. We present a case of a four-year-old indian girl with meningitis that presented a clinical deterioration with neurological signs while under antibiotics. The epidemiological history and the neuroimaging findings of incipient hydrocephalus, infarcts and probable tuberculomas, were essential to evoke the diagnosis of Tuberculous meningitis. Diagnosis of Tuberculous meningitis is difficult as it can clinically present similarly to other forms of meningitis. The recognition of this entity involves a high index of suspicion based on the previous referred findings and is essential in terms of morbidity and mortality.A meningite tuberculosa é a forma mais grave de tuberculose e o seu diagnóstico continua a ser um desafio. De facto, a maioria dos casos de meningite tuberculosa não podem ser diagnosticados com base nos achados clínicos e as técnicas laboratoriais são pouco sensíveis e morosas. A apresentação clínica pode ser inespecífica e sugerir outros diagnósticos. A dificuldade no diagnóstico frequentemente condiciona um atraso no tratamento e mortalidade subsequente. Apresentamos o caso de uma criança indiana de quatro anos com o diagnóstico de meningite que, sob antibioterapia, apresentou agravamento clínico com alterações neurológicas. A história epidemiológica e os achados de neuroimagem compatíveis com hidrocefalia incipiente, enfartes e prováveis ​​tuberculomas foram essenciais para evocar o diagnóstico de meningite tuberculosa. O diagnóstico de meningite tuberculosa é difícil, pois pode apresentar-se clinicamente de forma semelhante a outras formas de meningite. O reconhecimento desta entidade envolve um elevado índice de suspeição com base nos achados anteriormente referidos e é essencial na prevenção de morbilidade e mortalidade associadas.Sociedade Portuguesa de Pediatria2021-11-03info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25754/pjp.2021.21668eng2184-44532184-3333Lemos, Ana PereiraConstante, Andreia DuarteConceição, CarlaVieira, José PedroBrito, Maria Joãoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T02:58:14Zoai:ojs.revistas.rcaap.pt:article/21668Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:25:37.000105Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Tuberculous Meningitis: The Important Role of Imaging
Meningite tuberculosa: a importância dos exames de imagem
title Tuberculous Meningitis: The Important Role of Imaging
spellingShingle Tuberculous Meningitis: The Important Role of Imaging
Lemos, Ana Pereira
Case reports
title_short Tuberculous Meningitis: The Important Role of Imaging
title_full Tuberculous Meningitis: The Important Role of Imaging
title_fullStr Tuberculous Meningitis: The Important Role of Imaging
title_full_unstemmed Tuberculous Meningitis: The Important Role of Imaging
title_sort Tuberculous Meningitis: The Important Role of Imaging
author Lemos, Ana Pereira
author_facet Lemos, Ana Pereira
Constante, Andreia Duarte
Conceição, Carla
Vieira, José Pedro
Brito, Maria João
author_role author
author2 Constante, Andreia Duarte
Conceição, Carla
Vieira, José Pedro
Brito, Maria João
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Lemos, Ana Pereira
Constante, Andreia Duarte
Conceição, Carla
Vieira, José Pedro
Brito, Maria João
dc.subject.por.fl_str_mv Case reports
topic Case reports
description Tuberculous meningitis is the most severe form of tuberculosis and the diagnosis continues to be challenging for clinicians. Indeed, many cases of Tuberculous meningitis cannot be confirmed based on clinical findings and laboratory techniques are largely insensitive or slow. Clinical presentation can be nonspecific and suggest alternative conditions. The difficulty in diagnosis often leads to a delay in treatment and subsequent mortality. We present a case of a four-year-old indian girl with meningitis that presented a clinical deterioration with neurological signs while under antibiotics. The epidemiological history and the neuroimaging findings of incipient hydrocephalus, infarcts and probable tuberculomas, were essential to evoke the diagnosis of Tuberculous meningitis. Diagnosis of Tuberculous meningitis is difficult as it can clinically present similarly to other forms of meningitis. The recognition of this entity involves a high index of suspicion based on the previous referred findings and is essential in terms of morbidity and mortality.
publishDate 2021
dc.date.none.fl_str_mv 2021-11-03
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.language.iso.fl_str_mv eng
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dc.publisher.none.fl_str_mv Sociedade Portuguesa de Pediatria
publisher.none.fl_str_mv Sociedade Portuguesa de Pediatria
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