Influence of silicon, strontium and aluminum oxides on silicon nitride ceramics for bone replacements
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Matéria (Rio de Janeiro. Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-70762020000400336 |
Resumo: | ABSTRACT Although silicon nitride ceramics have been shown very propitious to be used for bone replacements, some characteristics can be controlled to improve their osseointegrations process. One of them is the intergranular phase whose composition can be specified to stimulate mineralization and osteoblastic production. In this paper, the intergranular glassy phase was projected in order to contain silicon, strontium and aluminum oxides. Silicon nitride samples containing different contents of SiO2, SrO and Al2O3 were sintered at 1815oC for 1 hour and characterized by scanning electron microscopy and X-ray diffraction. Hardness and fracture toughness were determined by Vickers hardness test and compressive strength was evaluated using an universal material testing machine. The biological behavior was studied in regard to cytotoxicity and cell proliferation by means of in vitro experiments. The samples reached high densities (higher than 95 %TD), total α→β-Si3N4 transformation, fracture toughness higher than 6.5 MPa.m1/2, compressive strength up to 2500 MPa and Vickers hardness less than 9.8 GPa. All samples were non-cytotoxic and able to promote cell proliferation with great potential to be used as components for bone replacements. However, that sample with high content of strontium had the best results of cell proliferation, proving the importance of a careful choice of intergranular phase composition in silicon nitride ceramics. |
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Influence of silicon, strontium and aluminum oxides on silicon nitride ceramics for bone replacementssilicon nitridemechanical propertiesosteoblastsABSTRACT Although silicon nitride ceramics have been shown very propitious to be used for bone replacements, some characteristics can be controlled to improve their osseointegrations process. One of them is the intergranular phase whose composition can be specified to stimulate mineralization and osteoblastic production. In this paper, the intergranular glassy phase was projected in order to contain silicon, strontium and aluminum oxides. Silicon nitride samples containing different contents of SiO2, SrO and Al2O3 were sintered at 1815oC for 1 hour and characterized by scanning electron microscopy and X-ray diffraction. Hardness and fracture toughness were determined by Vickers hardness test and compressive strength was evaluated using an universal material testing machine. The biological behavior was studied in regard to cytotoxicity and cell proliferation by means of in vitro experiments. The samples reached high densities (higher than 95 %TD), total α→β-Si3N4 transformation, fracture toughness higher than 6.5 MPa.m1/2, compressive strength up to 2500 MPa and Vickers hardness less than 9.8 GPa. All samples were non-cytotoxic and able to promote cell proliferation with great potential to be used as components for bone replacements. However, that sample with high content of strontium had the best results of cell proliferation, proving the importance of a careful choice of intergranular phase composition in silicon nitride ceramics.Laboratório de Hidrogênio, Coppe - Universidade Federal do Rio de Janeiroem cooperação com a Associação Brasileira do Hidrogênio, ABH22020-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-70762020000400336Matéria (Rio de Janeiro) v.25 n.4 2020reponame:Matéria (Rio de Janeiro. Online)instname:Matéria (Rio de Janeiro. Online)instacron:RLAM10.1590/s1517-707620200004.1178info:eu-repo/semantics/openAccessNascimento,Sergio Ferreira doRodas,Andrea Cecilia DorionCarvalho,Flávio Machado de SouzaHiga,Olga ZazucoSilva,Cecilia Chaves Guedes eeng2020-12-08T00:00:00Zoai:scielo:S1517-70762020000400336Revistahttp://www.materia.coppe.ufrj.br/https://old.scielo.br/oai/scielo-oai.php||materia@labh2.coppe.ufrj.br1517-70761517-7076opendoar:2020-12-08T00:00Matéria (Rio de Janeiro. Online) - Matéria (Rio de Janeiro. Online)false |
dc.title.none.fl_str_mv |
Influence of silicon, strontium and aluminum oxides on silicon nitride ceramics for bone replacements |
title |
Influence of silicon, strontium and aluminum oxides on silicon nitride ceramics for bone replacements |
spellingShingle |
Influence of silicon, strontium and aluminum oxides on silicon nitride ceramics for bone replacements Nascimento,Sergio Ferreira do silicon nitride mechanical properties osteoblasts |
title_short |
Influence of silicon, strontium and aluminum oxides on silicon nitride ceramics for bone replacements |
title_full |
Influence of silicon, strontium and aluminum oxides on silicon nitride ceramics for bone replacements |
title_fullStr |
Influence of silicon, strontium and aluminum oxides on silicon nitride ceramics for bone replacements |
title_full_unstemmed |
Influence of silicon, strontium and aluminum oxides on silicon nitride ceramics for bone replacements |
title_sort |
Influence of silicon, strontium and aluminum oxides on silicon nitride ceramics for bone replacements |
author |
Nascimento,Sergio Ferreira do |
author_facet |
Nascimento,Sergio Ferreira do Rodas,Andrea Cecilia Dorion Carvalho,Flávio Machado de Souza Higa,Olga Zazuco Silva,Cecilia Chaves Guedes e |
author_role |
author |
author2 |
Rodas,Andrea Cecilia Dorion Carvalho,Flávio Machado de Souza Higa,Olga Zazuco Silva,Cecilia Chaves Guedes e |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Nascimento,Sergio Ferreira do Rodas,Andrea Cecilia Dorion Carvalho,Flávio Machado de Souza Higa,Olga Zazuco Silva,Cecilia Chaves Guedes e |
dc.subject.por.fl_str_mv |
silicon nitride mechanical properties osteoblasts |
topic |
silicon nitride mechanical properties osteoblasts |
description |
ABSTRACT Although silicon nitride ceramics have been shown very propitious to be used for bone replacements, some characteristics can be controlled to improve their osseointegrations process. One of them is the intergranular phase whose composition can be specified to stimulate mineralization and osteoblastic production. In this paper, the intergranular glassy phase was projected in order to contain silicon, strontium and aluminum oxides. Silicon nitride samples containing different contents of SiO2, SrO and Al2O3 were sintered at 1815oC for 1 hour and characterized by scanning electron microscopy and X-ray diffraction. Hardness and fracture toughness were determined by Vickers hardness test and compressive strength was evaluated using an universal material testing machine. The biological behavior was studied in regard to cytotoxicity and cell proliferation by means of in vitro experiments. The samples reached high densities (higher than 95 %TD), total α→β-Si3N4 transformation, fracture toughness higher than 6.5 MPa.m1/2, compressive strength up to 2500 MPa and Vickers hardness less than 9.8 GPa. All samples were non-cytotoxic and able to promote cell proliferation with great potential to be used as components for bone replacements. However, that sample with high content of strontium had the best results of cell proliferation, proving the importance of a careful choice of intergranular phase composition in silicon nitride ceramics. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-70762020000400336 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-70762020000400336 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/s1517-707620200004.1178 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Laboratório de Hidrogênio, Coppe - Universidade Federal do Rio de Janeiro em cooperação com a Associação Brasileira do Hidrogênio, ABH2 |
publisher.none.fl_str_mv |
Laboratório de Hidrogênio, Coppe - Universidade Federal do Rio de Janeiro em cooperação com a Associação Brasileira do Hidrogênio, ABH2 |
dc.source.none.fl_str_mv |
Matéria (Rio de Janeiro) v.25 n.4 2020 reponame:Matéria (Rio de Janeiro. Online) instname:Matéria (Rio de Janeiro. Online) instacron:RLAM |
instname_str |
Matéria (Rio de Janeiro. Online) |
instacron_str |
RLAM |
institution |
RLAM |
reponame_str |
Matéria (Rio de Janeiro. Online) |
collection |
Matéria (Rio de Janeiro. Online) |
repository.name.fl_str_mv |
Matéria (Rio de Janeiro. Online) - Matéria (Rio de Janeiro. Online) |
repository.mail.fl_str_mv |
||materia@labh2.coppe.ufrj.br |
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1752126693765545984 |