Predictors of Arrhythmic Events Detected by Implantable Loop Recorders in Renal Transplant Candidates
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos Brasileiros de Cardiologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015002400493 |
Resumo: | AbstractBackground:The recording of arrhythmic events (AE) in renal transplant candidates (RTCs) undergoing dialysis is limited by conventional electrocardiography. However, continuous cardiac rhythm monitoring seems to be more appropriate due to automatic detection of arrhythmia, but this method has not been used.Objective:We aimed to investigate the incidence and predictors of AE in RTCs using an implantable loop recorder (ILR).Methods:A prospective observational study conducted from June 2009 to January 2011 included 100 consecutive ambulatory RTCs who underwent ILR and were followed-up for at least 1 year. Multivariate logistic regression was applied to define predictors of AE.Results:During a mean follow-up of 424 ± 127 days, AE could be detected in 98% of patients, and 92% had more than one type of arrhythmia, with most considered potentially not serious. Sustained atrial tachycardia and atrial fibrillation occurred in 7% and 13% of patients, respectively, and bradyarrhythmia and non-sustained or sustained ventricular tachycardia (VT) occurred in 25% and 57%, respectively. There were 18 deaths, of which 7 were sudden cardiac events: 3 bradyarrhythmias, 1 ventricular fibrillation, 1 myocardial infarction, and 2 undetermined. The presence of a long QTc (odds ratio [OR] = 7.28; 95% confidence interval [CI], 2.01–26.35; p = 0.002), and the duration of the PR interval (OR = 1.05; 95% CI, 1.02–1.08; p < 0.001) were independently associated with bradyarrhythmias. Left ventricular dilatation (LVD) was independently associated with non-sustained VT (OR = 2.83; 95% CI, 1.01–7.96; p = 0.041).Conclusions:In medium-term follow-up of RTCs, ILR helped detect a high incidence of AE, most of which did not have clinical relevance. The PR interval and presence of long QTc were predictive of bradyarrhythmias, whereas LVD was predictive of non-sustained VT. |
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Predictors of Arrhythmic Events Detected by Implantable Loop Recorders in Renal Transplant CandidatesArrhythmias, CardiacMyocardial ContractionKidney TransplantationDifibrillatorsElectric CountershockAbstractBackground:The recording of arrhythmic events (AE) in renal transplant candidates (RTCs) undergoing dialysis is limited by conventional electrocardiography. However, continuous cardiac rhythm monitoring seems to be more appropriate due to automatic detection of arrhythmia, but this method has not been used.Objective:We aimed to investigate the incidence and predictors of AE in RTCs using an implantable loop recorder (ILR).Methods:A prospective observational study conducted from June 2009 to January 2011 included 100 consecutive ambulatory RTCs who underwent ILR and were followed-up for at least 1 year. Multivariate logistic regression was applied to define predictors of AE.Results:During a mean follow-up of 424 ± 127 days, AE could be detected in 98% of patients, and 92% had more than one type of arrhythmia, with most considered potentially not serious. Sustained atrial tachycardia and atrial fibrillation occurred in 7% and 13% of patients, respectively, and bradyarrhythmia and non-sustained or sustained ventricular tachycardia (VT) occurred in 25% and 57%, respectively. There were 18 deaths, of which 7 were sudden cardiac events: 3 bradyarrhythmias, 1 ventricular fibrillation, 1 myocardial infarction, and 2 undetermined. The presence of a long QTc (odds ratio [OR] = 7.28; 95% confidence interval [CI], 2.01–26.35; p = 0.002), and the duration of the PR interval (OR = 1.05; 95% CI, 1.02–1.08; p < 0.001) were independently associated with bradyarrhythmias. Left ventricular dilatation (LVD) was independently associated with non-sustained VT (OR = 2.83; 95% CI, 1.01–7.96; p = 0.041).Conclusions:In medium-term follow-up of RTCs, ILR helped detect a high incidence of AE, most of which did not have clinical relevance. The PR interval and presence of long QTc were predictive of bradyarrhythmias, whereas LVD was predictive of non-sustained VT.Sociedade Brasileira de Cardiologia - SBC2015-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015002400493Arquivos Brasileiros de Cardiologia v.105 n.5 2015reponame:Arquivos Brasileiros de Cardiologia (Online)instname:Sociedade Brasileira de Cardiologia (SBC)instacron:SBC10.5935/abc.20150106info:eu-repo/semantics/openAccessSilva,Rodrigo TavaresMartinelli Filho,MartinoPeixoto,Giselle de LimaLima,José Jayme Galvão deSiqueira,Sérgio Freitas deCosta,RobertoGowdak,Luís Henrique WolffPaula,Flávio Jota deKalil Filho,RobertoRamires,José Antônio Franchinieng2015-11-13T00:00:00Zoai:scielo:S0066-782X2015002400493Revistahttp://www.arquivosonline.com.br/https://old.scielo.br/oai/scielo-oai.php||arquivos@cardiol.br1678-41700066-782Xopendoar:2015-11-13T00:00Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC)false |
dc.title.none.fl_str_mv |
Predictors of Arrhythmic Events Detected by Implantable Loop Recorders in Renal Transplant Candidates |
title |
Predictors of Arrhythmic Events Detected by Implantable Loop Recorders in Renal Transplant Candidates |
spellingShingle |
Predictors of Arrhythmic Events Detected by Implantable Loop Recorders in Renal Transplant Candidates Silva,Rodrigo Tavares Arrhythmias, Cardiac Myocardial Contraction Kidney Transplantation Difibrillators Electric Countershock |
title_short |
Predictors of Arrhythmic Events Detected by Implantable Loop Recorders in Renal Transplant Candidates |
title_full |
Predictors of Arrhythmic Events Detected by Implantable Loop Recorders in Renal Transplant Candidates |
title_fullStr |
Predictors of Arrhythmic Events Detected by Implantable Loop Recorders in Renal Transplant Candidates |
title_full_unstemmed |
Predictors of Arrhythmic Events Detected by Implantable Loop Recorders in Renal Transplant Candidates |
title_sort |
Predictors of Arrhythmic Events Detected by Implantable Loop Recorders in Renal Transplant Candidates |
author |
Silva,Rodrigo Tavares |
author_facet |
Silva,Rodrigo Tavares Martinelli Filho,Martino Peixoto,Giselle de Lima Lima,José Jayme Galvão de Siqueira,Sérgio Freitas de Costa,Roberto Gowdak,Luís Henrique Wolff Paula,Flávio Jota de Kalil Filho,Roberto Ramires,José Antônio Franchini |
author_role |
author |
author2 |
Martinelli Filho,Martino Peixoto,Giselle de Lima Lima,José Jayme Galvão de Siqueira,Sérgio Freitas de Costa,Roberto Gowdak,Luís Henrique Wolff Paula,Flávio Jota de Kalil Filho,Roberto Ramires,José Antônio Franchini |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Silva,Rodrigo Tavares Martinelli Filho,Martino Peixoto,Giselle de Lima Lima,José Jayme Galvão de Siqueira,Sérgio Freitas de Costa,Roberto Gowdak,Luís Henrique Wolff Paula,Flávio Jota de Kalil Filho,Roberto Ramires,José Antônio Franchini |
dc.subject.por.fl_str_mv |
Arrhythmias, Cardiac Myocardial Contraction Kidney Transplantation Difibrillators Electric Countershock |
topic |
Arrhythmias, Cardiac Myocardial Contraction Kidney Transplantation Difibrillators Electric Countershock |
description |
AbstractBackground:The recording of arrhythmic events (AE) in renal transplant candidates (RTCs) undergoing dialysis is limited by conventional electrocardiography. However, continuous cardiac rhythm monitoring seems to be more appropriate due to automatic detection of arrhythmia, but this method has not been used.Objective:We aimed to investigate the incidence and predictors of AE in RTCs using an implantable loop recorder (ILR).Methods:A prospective observational study conducted from June 2009 to January 2011 included 100 consecutive ambulatory RTCs who underwent ILR and were followed-up for at least 1 year. Multivariate logistic regression was applied to define predictors of AE.Results:During a mean follow-up of 424 ± 127 days, AE could be detected in 98% of patients, and 92% had more than one type of arrhythmia, with most considered potentially not serious. Sustained atrial tachycardia and atrial fibrillation occurred in 7% and 13% of patients, respectively, and bradyarrhythmia and non-sustained or sustained ventricular tachycardia (VT) occurred in 25% and 57%, respectively. There were 18 deaths, of which 7 were sudden cardiac events: 3 bradyarrhythmias, 1 ventricular fibrillation, 1 myocardial infarction, and 2 undetermined. The presence of a long QTc (odds ratio [OR] = 7.28; 95% confidence interval [CI], 2.01–26.35; p = 0.002), and the duration of the PR interval (OR = 1.05; 95% CI, 1.02–1.08; p < 0.001) were independently associated with bradyarrhythmias. Left ventricular dilatation (LVD) was independently associated with non-sustained VT (OR = 2.83; 95% CI, 1.01–7.96; p = 0.041).Conclusions:In medium-term follow-up of RTCs, ILR helped detect a high incidence of AE, most of which did not have clinical relevance. The PR interval and presence of long QTc were predictive of bradyarrhythmias, whereas LVD was predictive of non-sustained VT. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-11-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015002400493 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015002400493 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.5935/abc.20150106 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia - SBC |
publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia - SBC |
dc.source.none.fl_str_mv |
Arquivos Brasileiros de Cardiologia v.105 n.5 2015 reponame:Arquivos Brasileiros de Cardiologia (Online) instname:Sociedade Brasileira de Cardiologia (SBC) instacron:SBC |
instname_str |
Sociedade Brasileira de Cardiologia (SBC) |
instacron_str |
SBC |
institution |
SBC |
reponame_str |
Arquivos Brasileiros de Cardiologia (Online) |
collection |
Arquivos Brasileiros de Cardiologia (Online) |
repository.name.fl_str_mv |
Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC) |
repository.mail.fl_str_mv |
||arquivos@cardiol.br |
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1752126565708201984 |