Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure

Detalhes bibliográficos
Autor(a) principal: Villacorta,Humberto
Data de Publicação: 2016
Outros Autores: Maisel,Alan S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos Brasileiros de Cardiologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016000200145
Resumo: Abstract ST2 is a member of the interleukin-1 receptor family biomarker and circulating soluble ST2 concentrations are believed to reflect cardiovascular stress and fibrosis. Recent studies have demonstrated soluble ST2 to be a strong predictor of cardiovascular outcomes in both chronic and acute heart failure. It is a new biomarker that meets all required criteria for a useful biomarker. Of note, it adds information to natriuretic peptides (NPs) and some studies have shown it is even superior in terms of risk stratification. Since the introduction of NPs, this has been the most promising biomarker in the field of heart failure and might be particularly useful as therapy guide.
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spelling Soluble ST2 Testing: A Promising Biomarker in the Management of Heart FailureHeart Failure / therapyBiomarkers, PharmacologicalReceptors, InterleukinPrognosisAbstract ST2 is a member of the interleukin-1 receptor family biomarker and circulating soluble ST2 concentrations are believed to reflect cardiovascular stress and fibrosis. Recent studies have demonstrated soluble ST2 to be a strong predictor of cardiovascular outcomes in both chronic and acute heart failure. It is a new biomarker that meets all required criteria for a useful biomarker. Of note, it adds information to natriuretic peptides (NPs) and some studies have shown it is even superior in terms of risk stratification. Since the introduction of NPs, this has been the most promising biomarker in the field of heart failure and might be particularly useful as therapy guide.Sociedade Brasileira de Cardiologia - SBC2016-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016000200145Arquivos Brasileiros de Cardiologia v.106 n.2 2016reponame:Arquivos Brasileiros de Cardiologia (Online)instname:Sociedade Brasileira de Cardiologia (SBC)instacron:SBC10.5935/abc.20150151info:eu-repo/semantics/openAccessVillacorta,HumbertoMaisel,Alan S.eng2016-03-22T00:00:00Zoai:scielo:S0066-782X2016000200145Revistahttp://www.arquivosonline.com.br/https://old.scielo.br/oai/scielo-oai.php||arquivos@cardiol.br1678-41700066-782Xopendoar:2016-03-22T00:00Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC)false
dc.title.none.fl_str_mv Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure
title Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure
spellingShingle Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure
Villacorta,Humberto
Heart Failure / therapy
Biomarkers, Pharmacological
Receptors, Interleukin
Prognosis
title_short Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure
title_full Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure
title_fullStr Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure
title_full_unstemmed Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure
title_sort Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure
author Villacorta,Humberto
author_facet Villacorta,Humberto
Maisel,Alan S.
author_role author
author2 Maisel,Alan S.
author2_role author
dc.contributor.author.fl_str_mv Villacorta,Humberto
Maisel,Alan S.
dc.subject.por.fl_str_mv Heart Failure / therapy
Biomarkers, Pharmacological
Receptors, Interleukin
Prognosis
topic Heart Failure / therapy
Biomarkers, Pharmacological
Receptors, Interleukin
Prognosis
description Abstract ST2 is a member of the interleukin-1 receptor family biomarker and circulating soluble ST2 concentrations are believed to reflect cardiovascular stress and fibrosis. Recent studies have demonstrated soluble ST2 to be a strong predictor of cardiovascular outcomes in both chronic and acute heart failure. It is a new biomarker that meets all required criteria for a useful biomarker. Of note, it adds information to natriuretic peptides (NPs) and some studies have shown it is even superior in terms of risk stratification. Since the introduction of NPs, this has been the most promising biomarker in the field of heart failure and might be particularly useful as therapy guide.
publishDate 2016
dc.date.none.fl_str_mv 2016-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016000200145
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016000200145
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/abc.20150151
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Cardiologia - SBC
publisher.none.fl_str_mv Sociedade Brasileira de Cardiologia - SBC
dc.source.none.fl_str_mv Arquivos Brasileiros de Cardiologia v.106 n.2 2016
reponame:Arquivos Brasileiros de Cardiologia (Online)
instname:Sociedade Brasileira de Cardiologia (SBC)
instacron:SBC
instname_str Sociedade Brasileira de Cardiologia (SBC)
instacron_str SBC
institution SBC
reponame_str Arquivos Brasileiros de Cardiologia (Online)
collection Arquivos Brasileiros de Cardiologia (Online)
repository.name.fl_str_mv Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC)
repository.mail.fl_str_mv ||arquivos@cardiol.br
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