Left Atrial Volume Determinants in Patients with Non-Ischemic Dilated Cardiomyopathy
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos Brasileiros de Cardiologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015002000065 |
Resumo: | Background:Left atrial volume (LAV) is a predictor of prognosis in patients with heart failure.Objective:We aimed to evaluate the determinants of LAV in patients with dilated cardiomyopathy (DCM).Methods:Ninety patients with DCM and left ventricular (LV) ejection fraction ≤ 0.50 were included. LAV was measured with real-time three-dimensional echocardiography (eco3D). The variables evaluated were heart rate, systolic blood pressure, LV end-diastolic volume and end-systolic volume and ejection fraction (eco3D), mitral inflow E wave, tissue Doppler e´ wave, E/e´ ratio, intraventricular dyssynchrony, 3D dyssynchrony index and mitral regurgitation vena contracta. Pearson´s coefficient was used to identify the correlation of the LAV with the assessed variables. A multiple linear regression model was developed that included LAV as the dependent variable and the variables correlated with it as the predictive variables.Results:Mean age was 52 ± 11 years-old, LV ejection fraction: 31.5 ± 8.0% (16-50%) and LAV: 39.2±15.7 ml/m2. The variables that correlated with the LAV were LV end-diastolic volume (r = 0.38; p < 0.01), LV end-systolic volume (r = 0.43; p < 0.001), LV ejection fraction (r = -0.36; p < 0.01), E wave (r = 0.50; p < 0.01), E/e´ ratio (r = 0.51; p < 0.01) and mitral regurgitation (r = 0.53; p < 0.01). A multivariate analysis identified the E/e´ ratio (p = 0.02) and mitral regurgitation (p = 0.02) as the only independent variables associated with LAV increase.Conclusion:The LAV is independently determined by LV filling pressures (E/e´ ratio) and mitral regurgitation in DCM. |
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Left Atrial Volume Determinants in Patients with Non-Ischemic Dilated CardiomyopathyHeart AtriaOrgan SizeCardiomyopathy, DilatedChagas CardiomyopathyEchocardiography, Three-DimensionalBackground:Left atrial volume (LAV) is a predictor of prognosis in patients with heart failure.Objective:We aimed to evaluate the determinants of LAV in patients with dilated cardiomyopathy (DCM).Methods:Ninety patients with DCM and left ventricular (LV) ejection fraction ≤ 0.50 were included. LAV was measured with real-time three-dimensional echocardiography (eco3D). The variables evaluated were heart rate, systolic blood pressure, LV end-diastolic volume and end-systolic volume and ejection fraction (eco3D), mitral inflow E wave, tissue Doppler e´ wave, E/e´ ratio, intraventricular dyssynchrony, 3D dyssynchrony index and mitral regurgitation vena contracta. Pearson´s coefficient was used to identify the correlation of the LAV with the assessed variables. A multiple linear regression model was developed that included LAV as the dependent variable and the variables correlated with it as the predictive variables.Results:Mean age was 52 ± 11 years-old, LV ejection fraction: 31.5 ± 8.0% (16-50%) and LAV: 39.2±15.7 ml/m2. The variables that correlated with the LAV were LV end-diastolic volume (r = 0.38; p < 0.01), LV end-systolic volume (r = 0.43; p < 0.001), LV ejection fraction (r = -0.36; p < 0.01), E wave (r = 0.50; p < 0.01), E/e´ ratio (r = 0.51; p < 0.01) and mitral regurgitation (r = 0.53; p < 0.01). A multivariate analysis identified the E/e´ ratio (p = 0.02) and mitral regurgitation (p = 0.02) as the only independent variables associated with LAV increase.Conclusion:The LAV is independently determined by LV filling pressures (E/e´ ratio) and mitral regurgitation in DCM.Sociedade Brasileira de Cardiologia - SBC2015-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015002000065Arquivos Brasileiros de Cardiologia v.105 n.1 2015reponame:Arquivos Brasileiros de Cardiologia (Online)instname:Sociedade Brasileira de Cardiologia (SBC)instacron:SBC10.5935/abc.20150042info:eu-repo/semantics/openAccessMancuso,Frederico José NevesMoisés,Valdir AmbrósioAlmeida,Dirceu RodriguesPoyares,DalvaStorti,Luciana JulioOliveira,Wércules AntonioBrito,Flavio SouzaPaola,Angelo Amato Vincenzo deCarvalho,Antonio Carlos CamargoCampos,Orlandoeng2015-10-19T00:00:00Zoai:scielo:S0066-782X2015002000065Revistahttp://www.arquivosonline.com.br/https://old.scielo.br/oai/scielo-oai.php||arquivos@cardiol.br1678-41700066-782Xopendoar:2015-10-19T00:00Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC)false |
dc.title.none.fl_str_mv |
Left Atrial Volume Determinants in Patients with Non-Ischemic Dilated Cardiomyopathy |
title |
Left Atrial Volume Determinants in Patients with Non-Ischemic Dilated Cardiomyopathy |
spellingShingle |
Left Atrial Volume Determinants in Patients with Non-Ischemic Dilated Cardiomyopathy Mancuso,Frederico José Neves Heart Atria Organ Size Cardiomyopathy, Dilated Chagas Cardiomyopathy Echocardiography, Three-Dimensional |
title_short |
Left Atrial Volume Determinants in Patients with Non-Ischemic Dilated Cardiomyopathy |
title_full |
Left Atrial Volume Determinants in Patients with Non-Ischemic Dilated Cardiomyopathy |
title_fullStr |
Left Atrial Volume Determinants in Patients with Non-Ischemic Dilated Cardiomyopathy |
title_full_unstemmed |
Left Atrial Volume Determinants in Patients with Non-Ischemic Dilated Cardiomyopathy |
title_sort |
Left Atrial Volume Determinants in Patients with Non-Ischemic Dilated Cardiomyopathy |
author |
Mancuso,Frederico José Neves |
author_facet |
Mancuso,Frederico José Neves Moisés,Valdir Ambrósio Almeida,Dirceu Rodrigues Poyares,Dalva Storti,Luciana Julio Oliveira,Wércules Antonio Brito,Flavio Souza Paola,Angelo Amato Vincenzo de Carvalho,Antonio Carlos Camargo Campos,Orlando |
author_role |
author |
author2 |
Moisés,Valdir Ambrósio Almeida,Dirceu Rodrigues Poyares,Dalva Storti,Luciana Julio Oliveira,Wércules Antonio Brito,Flavio Souza Paola,Angelo Amato Vincenzo de Carvalho,Antonio Carlos Camargo Campos,Orlando |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Mancuso,Frederico José Neves Moisés,Valdir Ambrósio Almeida,Dirceu Rodrigues Poyares,Dalva Storti,Luciana Julio Oliveira,Wércules Antonio Brito,Flavio Souza Paola,Angelo Amato Vincenzo de Carvalho,Antonio Carlos Camargo Campos,Orlando |
dc.subject.por.fl_str_mv |
Heart Atria Organ Size Cardiomyopathy, Dilated Chagas Cardiomyopathy Echocardiography, Three-Dimensional |
topic |
Heart Atria Organ Size Cardiomyopathy, Dilated Chagas Cardiomyopathy Echocardiography, Three-Dimensional |
description |
Background:Left atrial volume (LAV) is a predictor of prognosis in patients with heart failure.Objective:We aimed to evaluate the determinants of LAV in patients with dilated cardiomyopathy (DCM).Methods:Ninety patients with DCM and left ventricular (LV) ejection fraction ≤ 0.50 were included. LAV was measured with real-time three-dimensional echocardiography (eco3D). The variables evaluated were heart rate, systolic blood pressure, LV end-diastolic volume and end-systolic volume and ejection fraction (eco3D), mitral inflow E wave, tissue Doppler e´ wave, E/e´ ratio, intraventricular dyssynchrony, 3D dyssynchrony index and mitral regurgitation vena contracta. Pearson´s coefficient was used to identify the correlation of the LAV with the assessed variables. A multiple linear regression model was developed that included LAV as the dependent variable and the variables correlated with it as the predictive variables.Results:Mean age was 52 ± 11 years-old, LV ejection fraction: 31.5 ± 8.0% (16-50%) and LAV: 39.2±15.7 ml/m2. The variables that correlated with the LAV were LV end-diastolic volume (r = 0.38; p < 0.01), LV end-systolic volume (r = 0.43; p < 0.001), LV ejection fraction (r = -0.36; p < 0.01), E wave (r = 0.50; p < 0.01), E/e´ ratio (r = 0.51; p < 0.01) and mitral regurgitation (r = 0.53; p < 0.01). A multivariate analysis identified the E/e´ ratio (p = 0.02) and mitral regurgitation (p = 0.02) as the only independent variables associated with LAV increase.Conclusion:The LAV is independently determined by LV filling pressures (E/e´ ratio) and mitral regurgitation in DCM. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-07-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015002000065 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015002000065 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.5935/abc.20150042 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia - SBC |
publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia - SBC |
dc.source.none.fl_str_mv |
Arquivos Brasileiros de Cardiologia v.105 n.1 2015 reponame:Arquivos Brasileiros de Cardiologia (Online) instname:Sociedade Brasileira de Cardiologia (SBC) instacron:SBC |
instname_str |
Sociedade Brasileira de Cardiologia (SBC) |
instacron_str |
SBC |
institution |
SBC |
reponame_str |
Arquivos Brasileiros de Cardiologia (Online) |
collection |
Arquivos Brasileiros de Cardiologia (Online) |
repository.name.fl_str_mv |
Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC) |
repository.mail.fl_str_mv |
||arquivos@cardiol.br |
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1752126565642141696 |