Predictors of mortality in cardiac surgery: brain natriuretic peptide type B
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Cardiovascular Surgery (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382015000200008 |
Resumo: | AbstractObjective:We evaluated whether the preoperative serum concentration of brain natriuretic peptide (BNP) is a predictor of in-hospital mortality in patients that underwent cardiac surgery.Methods:We continuously evaluated 488 patients that underwent cardiac valve surgery or coronary artery bypass grafting (CABG) between January of 2009 and July of 2012. Follow up of these patients were done prospectively for 30 days postoperatively.Results:Data analysis showed that the overall mortality rate was equal to 9.6%, Receiver Operating Charactheristic (ROC) curve analysis found the optimal cut-off value of BNP equal to 382 pg/mL for overall mortality (AUC=0.73, 95% CI=0.66 to 0.81, P<0.001). Multivariate analysis showed that the value of BNP higher than 382 pg/mL (P=0.033, HR=2.05, 95% CI=1.6 to 3.98) was an independent predictor of overall mortality at 30 days postoperatively.Conclusion:We concluded that the preoperative serum concentration of BNP is an independent predictor of mortality in patients undergoing valve surgery or coronary artery bypass graft. |
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Brazilian Journal of Cardiovascular Surgery (Online) |
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Predictors of mortality in cardiac surgery: brain natriuretic peptide type BNatriuretic PeptidesHospital MortalityCardiovascular Surgery ProceduresProspective StudiesAbstractObjective:We evaluated whether the preoperative serum concentration of brain natriuretic peptide (BNP) is a predictor of in-hospital mortality in patients that underwent cardiac surgery.Methods:We continuously evaluated 488 patients that underwent cardiac valve surgery or coronary artery bypass grafting (CABG) between January of 2009 and July of 2012. Follow up of these patients were done prospectively for 30 days postoperatively.Results:Data analysis showed that the overall mortality rate was equal to 9.6%, Receiver Operating Charactheristic (ROC) curve analysis found the optimal cut-off value of BNP equal to 382 pg/mL for overall mortality (AUC=0.73, 95% CI=0.66 to 0.81, P<0.001). Multivariate analysis showed that the value of BNP higher than 382 pg/mL (P=0.033, HR=2.05, 95% CI=1.6 to 3.98) was an independent predictor of overall mortality at 30 days postoperatively.Conclusion:We concluded that the preoperative serum concentration of BNP is an independent predictor of mortality in patients undergoing valve surgery or coronary artery bypass graft.Sociedade Brasileira de Cirurgia Cardiovascular2015-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382015000200008Brazilian Journal of Cardiovascular Surgery v.30 n.2 2015reponame:Brazilian Journal of Cardiovascular Surgery (Online)instname:Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV)instacron:SBCCV10.5935/1678-9741.20150008info:eu-repo/semantics/openAccessMurad Junior,Jamil AlliNakazone,Marcelo ArrudaMachado,Mauricio de NassauGodoy,Moacir Fernandes deeng2015-10-09T00:00:00Zoai:scielo:S0102-76382015000200008Revistahttp://www.rbccv.org.br/https://old.scielo.br/oai/scielo-oai.php||rosangela.monteiro@incor.usp.br|| domingo@braile.com.br|| brandau@braile.com.br1678-97410102-7638opendoar:2015-10-09T00:00Brazilian Journal of Cardiovascular Surgery (Online) - Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV)false |
dc.title.none.fl_str_mv |
Predictors of mortality in cardiac surgery: brain natriuretic peptide type B |
title |
Predictors of mortality in cardiac surgery: brain natriuretic peptide type B |
spellingShingle |
Predictors of mortality in cardiac surgery: brain natriuretic peptide type B Murad Junior,Jamil Alli Natriuretic Peptides Hospital Mortality Cardiovascular Surgery Procedures Prospective Studies |
title_short |
Predictors of mortality in cardiac surgery: brain natriuretic peptide type B |
title_full |
Predictors of mortality in cardiac surgery: brain natriuretic peptide type B |
title_fullStr |
Predictors of mortality in cardiac surgery: brain natriuretic peptide type B |
title_full_unstemmed |
Predictors of mortality in cardiac surgery: brain natriuretic peptide type B |
title_sort |
Predictors of mortality in cardiac surgery: brain natriuretic peptide type B |
author |
Murad Junior,Jamil Alli |
author_facet |
Murad Junior,Jamil Alli Nakazone,Marcelo Arruda Machado,Mauricio de Nassau Godoy,Moacir Fernandes de |
author_role |
author |
author2 |
Nakazone,Marcelo Arruda Machado,Mauricio de Nassau Godoy,Moacir Fernandes de |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Murad Junior,Jamil Alli Nakazone,Marcelo Arruda Machado,Mauricio de Nassau Godoy,Moacir Fernandes de |
dc.subject.por.fl_str_mv |
Natriuretic Peptides Hospital Mortality Cardiovascular Surgery Procedures Prospective Studies |
topic |
Natriuretic Peptides Hospital Mortality Cardiovascular Surgery Procedures Prospective Studies |
description |
AbstractObjective:We evaluated whether the preoperative serum concentration of brain natriuretic peptide (BNP) is a predictor of in-hospital mortality in patients that underwent cardiac surgery.Methods:We continuously evaluated 488 patients that underwent cardiac valve surgery or coronary artery bypass grafting (CABG) between January of 2009 and July of 2012. Follow up of these patients were done prospectively for 30 days postoperatively.Results:Data analysis showed that the overall mortality rate was equal to 9.6%, Receiver Operating Charactheristic (ROC) curve analysis found the optimal cut-off value of BNP equal to 382 pg/mL for overall mortality (AUC=0.73, 95% CI=0.66 to 0.81, P<0.001). Multivariate analysis showed that the value of BNP higher than 382 pg/mL (P=0.033, HR=2.05, 95% CI=1.6 to 3.98) was an independent predictor of overall mortality at 30 days postoperatively.Conclusion:We concluded that the preoperative serum concentration of BNP is an independent predictor of mortality in patients undergoing valve surgery or coronary artery bypass graft. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382015000200008 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382015000200008 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.5935/1678-9741.20150008 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Cirurgia Cardiovascular |
publisher.none.fl_str_mv |
Sociedade Brasileira de Cirurgia Cardiovascular |
dc.source.none.fl_str_mv |
Brazilian Journal of Cardiovascular Surgery v.30 n.2 2015 reponame:Brazilian Journal of Cardiovascular Surgery (Online) instname:Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV) instacron:SBCCV |
instname_str |
Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV) |
instacron_str |
SBCCV |
institution |
SBCCV |
reponame_str |
Brazilian Journal of Cardiovascular Surgery (Online) |
collection |
Brazilian Journal of Cardiovascular Surgery (Online) |
repository.name.fl_str_mv |
Brazilian Journal of Cardiovascular Surgery (Online) - Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV) |
repository.mail.fl_str_mv |
||rosangela.monteiro@incor.usp.br|| domingo@braile.com.br|| brandau@braile.com.br |
_version_ |
1752126598934429696 |