Vitiligo - Part 2 - classification, histopathology and treatment

Detalhes bibliográficos
Autor(a) principal: Faria,Adriane Reichert
Data de Publicação: 2014
Outros Autores: Tarlé,Roberto Gomes, Dellatorre,Gerson, Mira,Marcelo Távora, Castro,Caio Cesar Silva de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000500784
Resumo: In an unprecedented effort in the field of vitiligo, a global consensus resulted on a suggested new classification protocol for the disease. The main histopathological finding in vitiligo is the total absence of functioning melanocytes in the lesions, while the inflammatory cells most commonly found on the edges of the lesions are CD4+ and CD8+ T lymphocytes. Physical and pharmacological treatment strategies aim to control the autoimmune damage and stimulate melanocyte migration from the unaffected edges of lesions and the outer hair follicle root sheath to the affected skin; moreover, surgical treatments can be combined with topical and physical treatments.
id SBD-1_47b6123f6f7233113dd97270e1eb8f0e
oai_identifier_str oai:scielo:S0365-05962014000500784
network_acronym_str SBD-1
network_name_str Anais brasileiros de dermatologia (Online)
repository_id_str
spelling Vitiligo - Part 2 - classification, histopathology and treatmentHistologyTherapeuticsTreatment outcomeVitiligoIn an unprecedented effort in the field of vitiligo, a global consensus resulted on a suggested new classification protocol for the disease. The main histopathological finding in vitiligo is the total absence of functioning melanocytes in the lesions, while the inflammatory cells most commonly found on the edges of the lesions are CD4+ and CD8+ T lymphocytes. Physical and pharmacological treatment strategies aim to control the autoimmune damage and stimulate melanocyte migration from the unaffected edges of lesions and the outer hair follicle root sheath to the affected skin; moreover, surgical treatments can be combined with topical and physical treatments.Sociedade Brasileira de Dermatologia2014-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000500784Anais Brasileiros de Dermatologia v.89 n.5 2014reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20142717info:eu-repo/semantics/openAccessFaria,Adriane ReichertTarlé,Roberto GomesDellatorre,GersonMira,Marcelo TávoraCastro,Caio Cesar Silva deeng2014-09-16T00:00:00Zoai:scielo:S0365-05962014000500784Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2014-09-16T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Vitiligo - Part 2 - classification, histopathology and treatment
title Vitiligo - Part 2 - classification, histopathology and treatment
spellingShingle Vitiligo - Part 2 - classification, histopathology and treatment
Faria,Adriane Reichert
Histology
Therapeutics
Treatment outcome
Vitiligo
title_short Vitiligo - Part 2 - classification, histopathology and treatment
title_full Vitiligo - Part 2 - classification, histopathology and treatment
title_fullStr Vitiligo - Part 2 - classification, histopathology and treatment
title_full_unstemmed Vitiligo - Part 2 - classification, histopathology and treatment
title_sort Vitiligo - Part 2 - classification, histopathology and treatment
author Faria,Adriane Reichert
author_facet Faria,Adriane Reichert
Tarlé,Roberto Gomes
Dellatorre,Gerson
Mira,Marcelo Távora
Castro,Caio Cesar Silva de
author_role author
author2 Tarlé,Roberto Gomes
Dellatorre,Gerson
Mira,Marcelo Távora
Castro,Caio Cesar Silva de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Faria,Adriane Reichert
Tarlé,Roberto Gomes
Dellatorre,Gerson
Mira,Marcelo Távora
Castro,Caio Cesar Silva de
dc.subject.por.fl_str_mv Histology
Therapeutics
Treatment outcome
Vitiligo
topic Histology
Therapeutics
Treatment outcome
Vitiligo
description In an unprecedented effort in the field of vitiligo, a global consensus resulted on a suggested new classification protocol for the disease. The main histopathological finding in vitiligo is the total absence of functioning melanocytes in the lesions, while the inflammatory cells most commonly found on the edges of the lesions are CD4+ and CD8+ T lymphocytes. Physical and pharmacological treatment strategies aim to control the autoimmune damage and stimulate melanocyte migration from the unaffected edges of lesions and the outer hair follicle root sheath to the affected skin; moreover, surgical treatments can be combined with topical and physical treatments.
publishDate 2014
dc.date.none.fl_str_mv 2014-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000500784
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000500784
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20142717
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.89 n.5 2014
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
_version_ 1752126419873300480

Registros relacionados