Diffuse cutaneous melanosis: rare complication of metastatic melanoma

Detalhes bibliográficos
Autor(a) principal: Amaral,Ana Cristina Vervloet do
Data de Publicação: 2017
Outros Autores: Diniz,Lucia Martins, Lucas,Elton Almeida, Capeli,Rafaela Lorenzon de Aragão
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100062
Resumo: Abstract Diffuse cutaneous melanosis is a rare complication of metastatic melanoma related to a worse prognosis. There are few cases reported in the literature. Its pathogenesis has not been completely elucidated, although studies have suggested certain mechanisms for its occurrence. It is clinically manifested as a blue-gray discoloration of the skin and mucous membranes in a cephalo caudal progression and usually associated with melanuria. Skin and mucosa histopathology reveals only the presence of melanophages in the dermis, mainly perivascular, and free interstitial melanin. We report the case of a 68-year-old male with metastatic melanoma, diffuse hyperpigmentation of the skin and melanuria.
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spelling Diffuse cutaneous melanosis: rare complication of metastatic melanomaMelanosisMelanomaParaneoplastic syndromesAbstract Diffuse cutaneous melanosis is a rare complication of metastatic melanoma related to a worse prognosis. There are few cases reported in the literature. Its pathogenesis has not been completely elucidated, although studies have suggested certain mechanisms for its occurrence. It is clinically manifested as a blue-gray discoloration of the skin and mucous membranes in a cephalo caudal progression and usually associated with melanuria. Skin and mucosa histopathology reveals only the presence of melanophages in the dermis, mainly perivascular, and free interstitial melanin. We report the case of a 68-year-old male with metastatic melanoma, diffuse hyperpigmentation of the skin and melanuria.Sociedade Brasileira de Dermatologia2017-01-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100062Anais Brasileiros de Dermatologia v.92 n.5 suppl.1 2017reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20176097info:eu-repo/semantics/openAccessAmaral,Ana Cristina Vervloet doDiniz,Lucia MartinsLucas,Elton AlmeidaCapeli,Rafaela Lorenzon de Aragãoeng2017-12-13T00:00:00Zoai:scielo:S0365-05962017001100062Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2017-12-13T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Diffuse cutaneous melanosis: rare complication of metastatic melanoma
title Diffuse cutaneous melanosis: rare complication of metastatic melanoma
spellingShingle Diffuse cutaneous melanosis: rare complication of metastatic melanoma
Amaral,Ana Cristina Vervloet do
Melanosis
Melanoma
Paraneoplastic syndromes
title_short Diffuse cutaneous melanosis: rare complication of metastatic melanoma
title_full Diffuse cutaneous melanosis: rare complication of metastatic melanoma
title_fullStr Diffuse cutaneous melanosis: rare complication of metastatic melanoma
title_full_unstemmed Diffuse cutaneous melanosis: rare complication of metastatic melanoma
title_sort Diffuse cutaneous melanosis: rare complication of metastatic melanoma
author Amaral,Ana Cristina Vervloet do
author_facet Amaral,Ana Cristina Vervloet do
Diniz,Lucia Martins
Lucas,Elton Almeida
Capeli,Rafaela Lorenzon de Aragão
author_role author
author2 Diniz,Lucia Martins
Lucas,Elton Almeida
Capeli,Rafaela Lorenzon de Aragão
author2_role author
author
author
dc.contributor.author.fl_str_mv Amaral,Ana Cristina Vervloet do
Diniz,Lucia Martins
Lucas,Elton Almeida
Capeli,Rafaela Lorenzon de Aragão
dc.subject.por.fl_str_mv Melanosis
Melanoma
Paraneoplastic syndromes
topic Melanosis
Melanoma
Paraneoplastic syndromes
description Abstract Diffuse cutaneous melanosis is a rare complication of metastatic melanoma related to a worse prognosis. There are few cases reported in the literature. Its pathogenesis has not been completely elucidated, although studies have suggested certain mechanisms for its occurrence. It is clinically manifested as a blue-gray discoloration of the skin and mucous membranes in a cephalo caudal progression and usually associated with melanuria. Skin and mucosa histopathology reveals only the presence of melanophages in the dermis, mainly perivascular, and free interstitial melanin. We report the case of a 68-year-old male with metastatic melanoma, diffuse hyperpigmentation of the skin and melanuria.
publishDate 2017
dc.date.none.fl_str_mv 2017-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100062
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100062
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20176097
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.92 n.5 suppl.1 2017
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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