Primary systemic amyloidosis associated with multiple myeloma
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Anais brasileiros de dermatologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000100015 |
Resumo: | This case report is about a 48-year-old female patient with systemic amyloidosis and multiple myeloma simultaneously. Amyloid cutaneous infiltrative lesions like papules, nodules, or plaques with a serous-hemorrhagic aspect were found in the eyelids, neck and retroauricular region, among others. She had presented intermittent papular lesions on the upper eyelids one year before, which worsened following local trauma. A local skin biopsy showed amorphous and eosinophilic substance in the dermis. Congo red staining confirmed the amyloid deposits. Abnormal exams: proteinuria (570mg/24h), Bence-Jones proteinuria and clonal plasma cells (70%) found in myelogram. Following the diagnosis of multiple myeloma based on amyloid skin lesions, the patient was referred to the Hematology service and died 5 months after the diagnosis. |
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Anais brasileiros de dermatologia (Online) |
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Primary systemic amyloidosis associated with multiple myelomaAmyloidosisEyelidsMultiple myelomaSkinThis case report is about a 48-year-old female patient with systemic amyloidosis and multiple myeloma simultaneously. Amyloid cutaneous infiltrative lesions like papules, nodules, or plaques with a serous-hemorrhagic aspect were found in the eyelids, neck and retroauricular region, among others. She had presented intermittent papular lesions on the upper eyelids one year before, which worsened following local trauma. A local skin biopsy showed amorphous and eosinophilic substance in the dermis. Congo red staining confirmed the amyloid deposits. Abnormal exams: proteinuria (570mg/24h), Bence-Jones proteinuria and clonal plasma cells (70%) found in myelogram. Following the diagnosis of multiple myeloma based on amyloid skin lesions, the patient was referred to the Hematology service and died 5 months after the diagnosis.Sociedade Brasileira de Dermatologia2012-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000100015Anais Brasileiros de Dermatologia v.87 n.1 2012reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/S0365-05962012000100015info:eu-repo/semantics/openAccessOliveira,Ederson Valei Lopes dePozetti,Ana Carolina GarciaPozetti,Eurides Maria de OliveiraAntonio,João RobertoMichalany,Nilceo Schweryeng2012-04-02T00:00:00Zoai:scielo:S0365-05962012000100015Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2012-04-02T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false |
dc.title.none.fl_str_mv |
Primary systemic amyloidosis associated with multiple myeloma |
title |
Primary systemic amyloidosis associated with multiple myeloma |
spellingShingle |
Primary systemic amyloidosis associated with multiple myeloma Oliveira,Ederson Valei Lopes de Amyloidosis Eyelids Multiple myeloma Skin |
title_short |
Primary systemic amyloidosis associated with multiple myeloma |
title_full |
Primary systemic amyloidosis associated with multiple myeloma |
title_fullStr |
Primary systemic amyloidosis associated with multiple myeloma |
title_full_unstemmed |
Primary systemic amyloidosis associated with multiple myeloma |
title_sort |
Primary systemic amyloidosis associated with multiple myeloma |
author |
Oliveira,Ederson Valei Lopes de |
author_facet |
Oliveira,Ederson Valei Lopes de Pozetti,Ana Carolina Garcia Pozetti,Eurides Maria de Oliveira Antonio,João Roberto Michalany,Nilceo Schwery |
author_role |
author |
author2 |
Pozetti,Ana Carolina Garcia Pozetti,Eurides Maria de Oliveira Antonio,João Roberto Michalany,Nilceo Schwery |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Oliveira,Ederson Valei Lopes de Pozetti,Ana Carolina Garcia Pozetti,Eurides Maria de Oliveira Antonio,João Roberto Michalany,Nilceo Schwery |
dc.subject.por.fl_str_mv |
Amyloidosis Eyelids Multiple myeloma Skin |
topic |
Amyloidosis Eyelids Multiple myeloma Skin |
description |
This case report is about a 48-year-old female patient with systemic amyloidosis and multiple myeloma simultaneously. Amyloid cutaneous infiltrative lesions like papules, nodules, or plaques with a serous-hemorrhagic aspect were found in the eyelids, neck and retroauricular region, among others. She had presented intermittent papular lesions on the upper eyelids one year before, which worsened following local trauma. A local skin biopsy showed amorphous and eosinophilic substance in the dermis. Congo red staining confirmed the amyloid deposits. Abnormal exams: proteinuria (570mg/24h), Bence-Jones proteinuria and clonal plasma cells (70%) found in myelogram. Following the diagnosis of multiple myeloma based on amyloid skin lesions, the patient was referred to the Hematology service and died 5 months after the diagnosis. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000100015 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000100015 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0365-05962012000100015 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
dc.source.none.fl_str_mv |
Anais Brasileiros de Dermatologia v.87 n.1 2012 reponame:Anais brasileiros de dermatologia (Online) instname:Sociedade Brasileira de Dermatologia (SBD) instacron:SBD |
instname_str |
Sociedade Brasileira de Dermatologia (SBD) |
instacron_str |
SBD |
institution |
SBD |
reponame_str |
Anais brasileiros de dermatologia (Online) |
collection |
Anais brasileiros de dermatologia (Online) |
repository.name.fl_str_mv |
Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD) |
repository.mail.fl_str_mv |
abd@sbd.org.br||revista@sbd.org.br |
_version_ |
1752126417894637568 |