Improvement of bone repair in diabetic rats subjected to ƛ780 nm low-level laser therapy

Detalhes bibliográficos
Autor(a) principal: Nascimento,Marismar Fernandes do
Data de Publicação: 2015
Outros Autores: Almeida,Bernadeth Moda de, Cunha,John Lennon Silva, Valois,Rafael Barreto Vieira, Pinheiro,Juliana Campos, Ribeiro,Maria Amália Gonzaga, Lima,Sonia Oliveira, Albuquerque-Júnior,Ricardo Luiz Cavalcanti de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Cirúrgica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015001000660
Resumo: PURPOSE: To investigate the effect of low-level laser therapy on bone healing in diabetic rats. METHODS: Bone cavities (19 mm diameter) were performed in the femur of 72 alloxan-induced diabetic rats, which were assigned into four groups: CTR (non-diabetic control), DBT (diabetic) CTRL (non-diabetic irradiated) and DBTL (diabetic irradiated). Low-level laser therapy was performed every 48h for seven days. Animals were euthanized at seven, 18 and 30 days. Alkaline phosphatase serum levels and bone repair were analyzed. RESULTS: Low-level laser therapy significantly increased alkaline phosphatase in at seven and 18 days (p<0.001), and improved bone healing at seven (p<0.01), 18 (p<0.05) and 30 (p<0.01) in diabetic animals. In addition, bone healing in irradiated diabetic group was statistically similar to control group at 30 days (p>0.05). CONCLUSION: Low-level laser therapy increased the serum levels of alkaline phosphatase and improved bone healing in alloxan-induced diabetic rats.
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spelling Improvement of bone repair in diabetic rats subjected to ƛ780 nm low-level laser therapyLaser TherapyLow-LevelDiabetes MellitusExperimentalOsteogenesisAlkaline PhosphataseRats PURPOSE: To investigate the effect of low-level laser therapy on bone healing in diabetic rats. METHODS: Bone cavities (19 mm diameter) were performed in the femur of 72 alloxan-induced diabetic rats, which were assigned into four groups: CTR (non-diabetic control), DBT (diabetic) CTRL (non-diabetic irradiated) and DBTL (diabetic irradiated). Low-level laser therapy was performed every 48h for seven days. Animals were euthanized at seven, 18 and 30 days. Alkaline phosphatase serum levels and bone repair were analyzed. RESULTS: Low-level laser therapy significantly increased alkaline phosphatase in at seven and 18 days (p<0.001), and improved bone healing at seven (p<0.01), 18 (p<0.05) and 30 (p<0.01) in diabetic animals. In addition, bone healing in irradiated diabetic group was statistically similar to control group at 30 days (p>0.05). CONCLUSION: Low-level laser therapy increased the serum levels of alkaline phosphatase and improved bone healing in alloxan-induced diabetic rats.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2015-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015001000660Acta Cirúrgica Brasileira v.30 n.10 2015reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/S0102-865020150100000002info:eu-repo/semantics/openAccessNascimento,Marismar Fernandes doAlmeida,Bernadeth Moda deCunha,John Lennon SilvaValois,Rafael Barreto VieiraPinheiro,Juliana CamposRibeiro,Maria Amália GonzagaLima,Sonia OliveiraAlbuquerque-Júnior,Ricardo Luiz Cavalcanti deeng2016-01-05T00:00:00Zoai:scielo:S0102-86502015001000660Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2016-01-05T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false
dc.title.none.fl_str_mv Improvement of bone repair in diabetic rats subjected to ƛ780 nm low-level laser therapy
title Improvement of bone repair in diabetic rats subjected to ƛ780 nm low-level laser therapy
spellingShingle Improvement of bone repair in diabetic rats subjected to ƛ780 nm low-level laser therapy
Nascimento,Marismar Fernandes do
Laser Therapy
Low-Level
Diabetes Mellitus
Experimental
Osteogenesis
Alkaline Phosphatase
Rats
title_short Improvement of bone repair in diabetic rats subjected to ƛ780 nm low-level laser therapy
title_full Improvement of bone repair in diabetic rats subjected to ƛ780 nm low-level laser therapy
title_fullStr Improvement of bone repair in diabetic rats subjected to ƛ780 nm low-level laser therapy
title_full_unstemmed Improvement of bone repair in diabetic rats subjected to ƛ780 nm low-level laser therapy
title_sort Improvement of bone repair in diabetic rats subjected to ƛ780 nm low-level laser therapy
author Nascimento,Marismar Fernandes do
author_facet Nascimento,Marismar Fernandes do
Almeida,Bernadeth Moda de
Cunha,John Lennon Silva
Valois,Rafael Barreto Vieira
Pinheiro,Juliana Campos
Ribeiro,Maria Amália Gonzaga
Lima,Sonia Oliveira
Albuquerque-Júnior,Ricardo Luiz Cavalcanti de
author_role author
author2 Almeida,Bernadeth Moda de
Cunha,John Lennon Silva
Valois,Rafael Barreto Vieira
Pinheiro,Juliana Campos
Ribeiro,Maria Amália Gonzaga
Lima,Sonia Oliveira
Albuquerque-Júnior,Ricardo Luiz Cavalcanti de
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Nascimento,Marismar Fernandes do
Almeida,Bernadeth Moda de
Cunha,John Lennon Silva
Valois,Rafael Barreto Vieira
Pinheiro,Juliana Campos
Ribeiro,Maria Amália Gonzaga
Lima,Sonia Oliveira
Albuquerque-Júnior,Ricardo Luiz Cavalcanti de
dc.subject.por.fl_str_mv Laser Therapy
Low-Level
Diabetes Mellitus
Experimental
Osteogenesis
Alkaline Phosphatase
Rats
topic Laser Therapy
Low-Level
Diabetes Mellitus
Experimental
Osteogenesis
Alkaline Phosphatase
Rats
description PURPOSE: To investigate the effect of low-level laser therapy on bone healing in diabetic rats. METHODS: Bone cavities (19 mm diameter) were performed in the femur of 72 alloxan-induced diabetic rats, which were assigned into four groups: CTR (non-diabetic control), DBT (diabetic) CTRL (non-diabetic irradiated) and DBTL (diabetic irradiated). Low-level laser therapy was performed every 48h for seven days. Animals were euthanized at seven, 18 and 30 days. Alkaline phosphatase serum levels and bone repair were analyzed. RESULTS: Low-level laser therapy significantly increased alkaline phosphatase in at seven and 18 days (p<0.001), and improved bone healing at seven (p<0.01), 18 (p<0.05) and 30 (p<0.01) in diabetic animals. In addition, bone healing in irradiated diabetic group was statistically similar to control group at 30 days (p>0.05). CONCLUSION: Low-level laser therapy increased the serum levels of alkaline phosphatase and improved bone healing in alloxan-induced diabetic rats.
publishDate 2015
dc.date.none.fl_str_mv 2015-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015001000660
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015001000660
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-865020150100000002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv Acta Cirúrgica Brasileira v.30 n.10 2015
reponame:Acta Cirúrgica Brasileira (Online)
instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron:SBDPC
instname_str Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron_str SBDPC
institution SBDPC
reponame_str Acta Cirúrgica Brasileira (Online)
collection Acta Cirúrgica Brasileira (Online)
repository.name.fl_str_mv Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
repository.mail.fl_str_mv ||sgolden@terra.com.br
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