Effect of different commercial fat sources on brain, liver and blood lipid profiles of rats in growth phase
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Acta Cirúrgica Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017001201013 |
Resumo: | Abstract Purpose: To investigate the fatty acid content of different fat sources and evaluate the effect of them on plasma and hepatic lipids and on the fatty acid profile of the brain tissue of Wistar rats. Methods: Thirty male albino Wistar rats received for 59 days, the following diets: diet added of margarine with low content of polyunsaturated fatty acids (PUFA); diet added of margarine with high content of PUFA; diet added of butter; diet added of hydrogenated vegetable fat; diet added of soybean oil. Fatty acid profile of the lipid sources, blood and hepatic lipids fractions and fatty acid profile of the brain tissue were determined. Results: Margarine consumption of provided different responses as to concentrations of blood and hepatic lipid fractions. Intake of butter and hydrogenated increased LDL-c/HDL-c ratio, being the steepest increase promoted by hydrogenated vegetable fat, which also raised LDL-c levels expressively. All fats used in the treatments reduced the cerebral concentration of docosahexaenoic acid when compared to soybean oil (control). Conclusion: The different fat sources commonly consumed by population provided different responses in vivo. This is particularly relevant considering the role of these lipids in the incidence and prevention of cardiovascular diseases. |
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Acta Cirúrgica Brasileira (Online) |
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Effect of different commercial fat sources on brain, liver and blood lipid profiles of rats in growth phaseDyslipidemiasLipid MetabolismRats.Abstract Purpose: To investigate the fatty acid content of different fat sources and evaluate the effect of them on plasma and hepatic lipids and on the fatty acid profile of the brain tissue of Wistar rats. Methods: Thirty male albino Wistar rats received for 59 days, the following diets: diet added of margarine with low content of polyunsaturated fatty acids (PUFA); diet added of margarine with high content of PUFA; diet added of butter; diet added of hydrogenated vegetable fat; diet added of soybean oil. Fatty acid profile of the lipid sources, blood and hepatic lipids fractions and fatty acid profile of the brain tissue were determined. Results: Margarine consumption of provided different responses as to concentrations of blood and hepatic lipid fractions. Intake of butter and hydrogenated increased LDL-c/HDL-c ratio, being the steepest increase promoted by hydrogenated vegetable fat, which also raised LDL-c levels expressively. All fats used in the treatments reduced the cerebral concentration of docosahexaenoic acid when compared to soybean oil (control). Conclusion: The different fat sources commonly consumed by population provided different responses in vivo. This is particularly relevant considering the role of these lipids in the incidence and prevention of cardiovascular diseases.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2017-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017001201013Acta Cirúrgica Brasileira v.32 n.12 2017reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/s0102-865020170120000003info:eu-repo/semantics/openAccessAngelis-Pereira,Michel Cardoso deBarcelos,Maria de Fátima PíccoloPereira,Juciane de Abreu RibeiroPereira,Rafaela CorrêaSouza,Raimundo Vicente deeng2018-03-01T00:00:00Zoai:scielo:S0102-86502017001201013Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2018-03-01T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false |
dc.title.none.fl_str_mv |
Effect of different commercial fat sources on brain, liver and blood lipid profiles of rats in growth phase |
title |
Effect of different commercial fat sources on brain, liver and blood lipid profiles of rats in growth phase |
spellingShingle |
Effect of different commercial fat sources on brain, liver and blood lipid profiles of rats in growth phase Angelis-Pereira,Michel Cardoso de Dyslipidemias Lipid Metabolism Rats. |
title_short |
Effect of different commercial fat sources on brain, liver and blood lipid profiles of rats in growth phase |
title_full |
Effect of different commercial fat sources on brain, liver and blood lipid profiles of rats in growth phase |
title_fullStr |
Effect of different commercial fat sources on brain, liver and blood lipid profiles of rats in growth phase |
title_full_unstemmed |
Effect of different commercial fat sources on brain, liver and blood lipid profiles of rats in growth phase |
title_sort |
Effect of different commercial fat sources on brain, liver and blood lipid profiles of rats in growth phase |
author |
Angelis-Pereira,Michel Cardoso de |
author_facet |
Angelis-Pereira,Michel Cardoso de Barcelos,Maria de Fátima Píccolo Pereira,Juciane de Abreu Ribeiro Pereira,Rafaela Corrêa Souza,Raimundo Vicente de |
author_role |
author |
author2 |
Barcelos,Maria de Fátima Píccolo Pereira,Juciane de Abreu Ribeiro Pereira,Rafaela Corrêa Souza,Raimundo Vicente de |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Angelis-Pereira,Michel Cardoso de Barcelos,Maria de Fátima Píccolo Pereira,Juciane de Abreu Ribeiro Pereira,Rafaela Corrêa Souza,Raimundo Vicente de |
dc.subject.por.fl_str_mv |
Dyslipidemias Lipid Metabolism Rats. |
topic |
Dyslipidemias Lipid Metabolism Rats. |
description |
Abstract Purpose: To investigate the fatty acid content of different fat sources and evaluate the effect of them on plasma and hepatic lipids and on the fatty acid profile of the brain tissue of Wistar rats. Methods: Thirty male albino Wistar rats received for 59 days, the following diets: diet added of margarine with low content of polyunsaturated fatty acids (PUFA); diet added of margarine with high content of PUFA; diet added of butter; diet added of hydrogenated vegetable fat; diet added of soybean oil. Fatty acid profile of the lipid sources, blood and hepatic lipids fractions and fatty acid profile of the brain tissue were determined. Results: Margarine consumption of provided different responses as to concentrations of blood and hepatic lipid fractions. Intake of butter and hydrogenated increased LDL-c/HDL-c ratio, being the steepest increase promoted by hydrogenated vegetable fat, which also raised LDL-c levels expressively. All fats used in the treatments reduced the cerebral concentration of docosahexaenoic acid when compared to soybean oil (control). Conclusion: The different fat sources commonly consumed by population provided different responses in vivo. This is particularly relevant considering the role of these lipids in the incidence and prevention of cardiovascular diseases. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017001201013 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017001201013 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/s0102-865020170120000003 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
dc.source.none.fl_str_mv |
Acta Cirúrgica Brasileira v.32 n.12 2017 reponame:Acta Cirúrgica Brasileira (Online) instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) instacron:SBDPC |
instname_str |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) |
instacron_str |
SBDPC |
institution |
SBDPC |
reponame_str |
Acta Cirúrgica Brasileira (Online) |
collection |
Acta Cirúrgica Brasileira (Online) |
repository.name.fl_str_mv |
Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) |
repository.mail.fl_str_mv |
||sgolden@terra.com.br |
_version_ |
1752126444549439488 |