Peroneal nerve reconstruction by using glycerol-preserved veins: histological and functional assessment in rats

Detalhes bibliográficos
Autor(a) principal: Cunha,Armando dos Santos
Data de Publicação: 2013
Outros Autores: Costa,Marcio Paulino, Da Silva,Ciro Ferreira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Cirúrgica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000200002
Resumo: PURPOSE: To compare the degree of neural regeneration in rats upon interposition of autologous nerve graft, autogenous vein, glycerol-preserved autogenous vein, and glycerol-preserved allogeneic vein using qualitative and quantitative histological analyses as well as functional assessments. METHODS: Peroneal nerves were reconstructed differently in four groups of animals. Functional assessments were performed pre- and postoperatively for a period of six weeks. After six weeks, the animals were sacrificed and histological evaluations were performed. RESULTS: Histological patterns of autogenous veins without preservation showed pronounced neoangiogenesis and extensive axonal rarefaction, as confirmed by axonal counting and functional assessments. Glycerol-preserved veins had results similar to the control. CONCLUSIONS: Glycerol-preserved autogenous or allogeneic veins showed similar results to autograft results. The autogenous vein (without preservation in glycerol) presented histological and functional outcomes statistically lower than other groups.
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spelling Peroneal nerve reconstruction by using glycerol-preserved veins: histological and functional assessment in ratsPeroneal NervePeripheral Nerves/surgeryNerve RegenerationReconstructive Surgical ProceduresGlycerolBlood VesselsTransplantation, HomologousRatsPURPOSE: To compare the degree of neural regeneration in rats upon interposition of autologous nerve graft, autogenous vein, glycerol-preserved autogenous vein, and glycerol-preserved allogeneic vein using qualitative and quantitative histological analyses as well as functional assessments. METHODS: Peroneal nerves were reconstructed differently in four groups of animals. Functional assessments were performed pre- and postoperatively for a period of six weeks. After six weeks, the animals were sacrificed and histological evaluations were performed. RESULTS: Histological patterns of autogenous veins without preservation showed pronounced neoangiogenesis and extensive axonal rarefaction, as confirmed by axonal counting and functional assessments. Glycerol-preserved veins had results similar to the control. CONCLUSIONS: Glycerol-preserved autogenous or allogeneic veins showed similar results to autograft results. The autogenous vein (without preservation in glycerol) presented histological and functional outcomes statistically lower than other groups.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2013-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000200002Acta Cirúrgica Brasileira v.28 n.2 2013reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/S0102-86502013000200002info:eu-repo/semantics/openAccessCunha,Armando dos SantosCosta,Marcio PaulinoDa Silva,Ciro Ferreiraeng2013-01-29T00:00:00Zoai:scielo:S0102-86502013000200002Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2013-01-29T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false
dc.title.none.fl_str_mv Peroneal nerve reconstruction by using glycerol-preserved veins: histological and functional assessment in rats
title Peroneal nerve reconstruction by using glycerol-preserved veins: histological and functional assessment in rats
spellingShingle Peroneal nerve reconstruction by using glycerol-preserved veins: histological and functional assessment in rats
Cunha,Armando dos Santos
Peroneal Nerve
Peripheral Nerves/surgery
Nerve Regeneration
Reconstructive Surgical Procedures
Glycerol
Blood Vessels
Transplantation, Homologous
Rats
title_short Peroneal nerve reconstruction by using glycerol-preserved veins: histological and functional assessment in rats
title_full Peroneal nerve reconstruction by using glycerol-preserved veins: histological and functional assessment in rats
title_fullStr Peroneal nerve reconstruction by using glycerol-preserved veins: histological and functional assessment in rats
title_full_unstemmed Peroneal nerve reconstruction by using glycerol-preserved veins: histological and functional assessment in rats
title_sort Peroneal nerve reconstruction by using glycerol-preserved veins: histological and functional assessment in rats
author Cunha,Armando dos Santos
author_facet Cunha,Armando dos Santos
Costa,Marcio Paulino
Da Silva,Ciro Ferreira
author_role author
author2 Costa,Marcio Paulino
Da Silva,Ciro Ferreira
author2_role author
author
dc.contributor.author.fl_str_mv Cunha,Armando dos Santos
Costa,Marcio Paulino
Da Silva,Ciro Ferreira
dc.subject.por.fl_str_mv Peroneal Nerve
Peripheral Nerves/surgery
Nerve Regeneration
Reconstructive Surgical Procedures
Glycerol
Blood Vessels
Transplantation, Homologous
Rats
topic Peroneal Nerve
Peripheral Nerves/surgery
Nerve Regeneration
Reconstructive Surgical Procedures
Glycerol
Blood Vessels
Transplantation, Homologous
Rats
description PURPOSE: To compare the degree of neural regeneration in rats upon interposition of autologous nerve graft, autogenous vein, glycerol-preserved autogenous vein, and glycerol-preserved allogeneic vein using qualitative and quantitative histological analyses as well as functional assessments. METHODS: Peroneal nerves were reconstructed differently in four groups of animals. Functional assessments were performed pre- and postoperatively for a period of six weeks. After six weeks, the animals were sacrificed and histological evaluations were performed. RESULTS: Histological patterns of autogenous veins without preservation showed pronounced neoangiogenesis and extensive axonal rarefaction, as confirmed by axonal counting and functional assessments. Glycerol-preserved veins had results similar to the control. CONCLUSIONS: Glycerol-preserved autogenous or allogeneic veins showed similar results to autograft results. The autogenous vein (without preservation in glycerol) presented histological and functional outcomes statistically lower than other groups.
publishDate 2013
dc.date.none.fl_str_mv 2013-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000200002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000200002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-86502013000200002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv Acta Cirúrgica Brasileira v.28 n.2 2013
reponame:Acta Cirúrgica Brasileira (Online)
instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron:SBDPC
instname_str Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron_str SBDPC
institution SBDPC
reponame_str Acta Cirúrgica Brasileira (Online)
collection Acta Cirúrgica Brasileira (Online)
repository.name.fl_str_mv Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
repository.mail.fl_str_mv ||sgolden@terra.com.br
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