Capsiate treatment in liver surgeries may compromise its recovery

Detalhes bibliográficos
Autor(a) principal: Barros,Pedro Paulo
Data de Publicação: 2018
Outros Autores: Gonçalves,Gisele Mara Silva, Silva,Gustavo Henrique da, Bastos,Maria Clara Villaça Dias, Ramos,Loren Nogaroto, Fernandes,Marilia Marinello
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Cirúrgica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502018000500439
Resumo: Abstract Purpose: To investigate the effects of capsiate treatment on hepatic hyperplasia in partially hepatectomized rats. Methods: The animals were divided into a Capsiate group (CPH), a Capsiate Post-Partial Hepatectomy group (CPPH) and a Partial Hepatectomy Control group (PH). CPH and CPPH animals received 60 mg/kg/day Capsiate for 30 days. Next, the rats underwent partial hepatectomy. CPPH animals continued to receive treatment for 48 h after partial hepatectomy. Liver tissue and intracardiac blood samples were obtained 24 or 48 h after PH. Results: Capsiate treatment interfered with hepatic parameters, reducing the number of mitoses and apoptosis and increasing blood ALT and alkaline phosphatase concentrations. Conclusion: Capsiate treatment preceding hepatic surgery may compromise the initial period of postoperative recovery.
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spelling Capsiate treatment in liver surgeries may compromise its recoveryAlanine TransaminaseAspartate AminotransferasesApoptosisMitotic IndexRats.Abstract Purpose: To investigate the effects of capsiate treatment on hepatic hyperplasia in partially hepatectomized rats. Methods: The animals were divided into a Capsiate group (CPH), a Capsiate Post-Partial Hepatectomy group (CPPH) and a Partial Hepatectomy Control group (PH). CPH and CPPH animals received 60 mg/kg/day Capsiate for 30 days. Next, the rats underwent partial hepatectomy. CPPH animals continued to receive treatment for 48 h after partial hepatectomy. Liver tissue and intracardiac blood samples were obtained 24 or 48 h after PH. Results: Capsiate treatment interfered with hepatic parameters, reducing the number of mitoses and apoptosis and increasing blood ALT and alkaline phosphatase concentrations. Conclusion: Capsiate treatment preceding hepatic surgery may compromise the initial period of postoperative recovery.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2018-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502018000500439Acta Cirúrgica Brasileira v.33 n.5 2018reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/s0102-865020180050000006info:eu-repo/semantics/openAccessBarros,Pedro PauloGonçalves,Gisele Mara SilvaSilva,Gustavo Henrique daBastos,Maria Clara Villaça DiasRamos,Loren NogarotoFernandes,Marilia Marinelloeng2018-06-08T00:00:00Zoai:scielo:S0102-86502018000500439Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2018-06-08T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false
dc.title.none.fl_str_mv Capsiate treatment in liver surgeries may compromise its recovery
title Capsiate treatment in liver surgeries may compromise its recovery
spellingShingle Capsiate treatment in liver surgeries may compromise its recovery
Barros,Pedro Paulo
Alanine Transaminase
Aspartate Aminotransferases
Apoptosis
Mitotic Index
Rats.
title_short Capsiate treatment in liver surgeries may compromise its recovery
title_full Capsiate treatment in liver surgeries may compromise its recovery
title_fullStr Capsiate treatment in liver surgeries may compromise its recovery
title_full_unstemmed Capsiate treatment in liver surgeries may compromise its recovery
title_sort Capsiate treatment in liver surgeries may compromise its recovery
author Barros,Pedro Paulo
author_facet Barros,Pedro Paulo
Gonçalves,Gisele Mara Silva
Silva,Gustavo Henrique da
Bastos,Maria Clara Villaça Dias
Ramos,Loren Nogaroto
Fernandes,Marilia Marinello
author_role author
author2 Gonçalves,Gisele Mara Silva
Silva,Gustavo Henrique da
Bastos,Maria Clara Villaça Dias
Ramos,Loren Nogaroto
Fernandes,Marilia Marinello
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Barros,Pedro Paulo
Gonçalves,Gisele Mara Silva
Silva,Gustavo Henrique da
Bastos,Maria Clara Villaça Dias
Ramos,Loren Nogaroto
Fernandes,Marilia Marinello
dc.subject.por.fl_str_mv Alanine Transaminase
Aspartate Aminotransferases
Apoptosis
Mitotic Index
Rats.
topic Alanine Transaminase
Aspartate Aminotransferases
Apoptosis
Mitotic Index
Rats.
description Abstract Purpose: To investigate the effects of capsiate treatment on hepatic hyperplasia in partially hepatectomized rats. Methods: The animals were divided into a Capsiate group (CPH), a Capsiate Post-Partial Hepatectomy group (CPPH) and a Partial Hepatectomy Control group (PH). CPH and CPPH animals received 60 mg/kg/day Capsiate for 30 days. Next, the rats underwent partial hepatectomy. CPPH animals continued to receive treatment for 48 h after partial hepatectomy. Liver tissue and intracardiac blood samples were obtained 24 or 48 h after PH. Results: Capsiate treatment interfered with hepatic parameters, reducing the number of mitoses and apoptosis and increasing blood ALT and alkaline phosphatase concentrations. Conclusion: Capsiate treatment preceding hepatic surgery may compromise the initial period of postoperative recovery.
publishDate 2018
dc.date.none.fl_str_mv 2018-05-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502018000500439
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502018000500439
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/s0102-865020180050000006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv Acta Cirúrgica Brasileira v.33 n.5 2018
reponame:Acta Cirúrgica Brasileira (Online)
instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron:SBDPC
instname_str Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron_str SBDPC
institution SBDPC
reponame_str Acta Cirúrgica Brasileira (Online)
collection Acta Cirúrgica Brasileira (Online)
repository.name.fl_str_mv Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
repository.mail.fl_str_mv ||sgolden@terra.com.br
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