Anatomo-radiological correlation using 18-FDG-PET in abdominal sepsis model in rats. A preliminary study

Detalhes bibliográficos
Autor(a) principal: Azevedo,Ítalo Medeiros
Data de Publicação: 2017
Outros Autores: Carvalho,Marília Daniela Ferreira, Nascimento,Rafael Pereira, Macedo,Robson, Aquino,Mônica Raquel de Souza, Medeiros,Aldo Cunha
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Cirúrgica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017000300175
Resumo: Abstract Purpose: To examine a correlation of micro-PET images with photographic images of the digestive organs in abdominal sepsis model. Methods: Male Wistar rats weighing 265±18g were used. Abdominal sepsis was induced by ligature and cecal puncture. Micro-PET Images from abdominal cavity septic foci were obtained using 18-Fluoro-deoxyglucose, looking for a correlation with photographic images of abdominal cavity organs. Pearson's correlation test was used. Results: The mean standard uptake values (SUV) and lesion areas were 2.58±0.63SUVbwg/ml and 546.87±300.95mm2, respectively. There was a strong positive correlation between the two variables (r=0.863, p=0.137), which resulted in a coefficient of determination r2?0.75, meaning that 75% of SUV variation is explained by the lesion areas of digestive organs. Conclusion: Micro-PET allows high throughput assessment of lesion count and volume in pre-clinical rat model of CPL abdominal sepsis.
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spelling Anatomo-radiological correlation using 18-FDG-PET in abdominal sepsis model in rats. A preliminary studySepsisFluorodeoxyglucose F18Positron-Emission TomographyRats.Abstract Purpose: To examine a correlation of micro-PET images with photographic images of the digestive organs in abdominal sepsis model. Methods: Male Wistar rats weighing 265±18g were used. Abdominal sepsis was induced by ligature and cecal puncture. Micro-PET Images from abdominal cavity septic foci were obtained using 18-Fluoro-deoxyglucose, looking for a correlation with photographic images of abdominal cavity organs. Pearson's correlation test was used. Results: The mean standard uptake values (SUV) and lesion areas were 2.58±0.63SUVbwg/ml and 546.87±300.95mm2, respectively. There was a strong positive correlation between the two variables (r=0.863, p=0.137), which resulted in a coefficient of determination r2?0.75, meaning that 75% of SUV variation is explained by the lesion areas of digestive organs. Conclusion: Micro-PET allows high throughput assessment of lesion count and volume in pre-clinical rat model of CPL abdominal sepsis.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2017-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017000300175Acta Cirúrgica Brasileira v.32 n.3 2017reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/s0102-865020170030000001info:eu-repo/semantics/openAccessAzevedo,Ítalo MedeirosCarvalho,Marília Daniela FerreiraNascimento,Rafael PereiraMacedo,RobsonAquino,Mônica Raquel de SouzaMedeiros,Aldo Cunhaeng2017-04-04T00:00:00Zoai:scielo:S0102-86502017000300175Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2017-04-04T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false
dc.title.none.fl_str_mv Anatomo-radiological correlation using 18-FDG-PET in abdominal sepsis model in rats. A preliminary study
title Anatomo-radiological correlation using 18-FDG-PET in abdominal sepsis model in rats. A preliminary study
spellingShingle Anatomo-radiological correlation using 18-FDG-PET in abdominal sepsis model in rats. A preliminary study
Azevedo,Ítalo Medeiros
Sepsis
Fluorodeoxyglucose F18
Positron-Emission Tomography
Rats.
title_short Anatomo-radiological correlation using 18-FDG-PET in abdominal sepsis model in rats. A preliminary study
title_full Anatomo-radiological correlation using 18-FDG-PET in abdominal sepsis model in rats. A preliminary study
title_fullStr Anatomo-radiological correlation using 18-FDG-PET in abdominal sepsis model in rats. A preliminary study
title_full_unstemmed Anatomo-radiological correlation using 18-FDG-PET in abdominal sepsis model in rats. A preliminary study
title_sort Anatomo-radiological correlation using 18-FDG-PET in abdominal sepsis model in rats. A preliminary study
author Azevedo,Ítalo Medeiros
author_facet Azevedo,Ítalo Medeiros
Carvalho,Marília Daniela Ferreira
Nascimento,Rafael Pereira
Macedo,Robson
Aquino,Mônica Raquel de Souza
Medeiros,Aldo Cunha
author_role author
author2 Carvalho,Marília Daniela Ferreira
Nascimento,Rafael Pereira
Macedo,Robson
Aquino,Mônica Raquel de Souza
Medeiros,Aldo Cunha
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Azevedo,Ítalo Medeiros
Carvalho,Marília Daniela Ferreira
Nascimento,Rafael Pereira
Macedo,Robson
Aquino,Mônica Raquel de Souza
Medeiros,Aldo Cunha
dc.subject.por.fl_str_mv Sepsis
Fluorodeoxyglucose F18
Positron-Emission Tomography
Rats.
topic Sepsis
Fluorodeoxyglucose F18
Positron-Emission Tomography
Rats.
description Abstract Purpose: To examine a correlation of micro-PET images with photographic images of the digestive organs in abdominal sepsis model. Methods: Male Wistar rats weighing 265±18g were used. Abdominal sepsis was induced by ligature and cecal puncture. Micro-PET Images from abdominal cavity septic foci were obtained using 18-Fluoro-deoxyglucose, looking for a correlation with photographic images of abdominal cavity organs. Pearson's correlation test was used. Results: The mean standard uptake values (SUV) and lesion areas were 2.58±0.63SUVbwg/ml and 546.87±300.95mm2, respectively. There was a strong positive correlation between the two variables (r=0.863, p=0.137), which resulted in a coefficient of determination r2?0.75, meaning that 75% of SUV variation is explained by the lesion areas of digestive organs. Conclusion: Micro-PET allows high throughput assessment of lesion count and volume in pre-clinical rat model of CPL abdominal sepsis.
publishDate 2017
dc.date.none.fl_str_mv 2017-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017000300175
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017000300175
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/s0102-865020170030000001
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv Acta Cirúrgica Brasileira v.32 n.3 2017
reponame:Acta Cirúrgica Brasileira (Online)
instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron:SBDPC
instname_str Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron_str SBDPC
institution SBDPC
reponame_str Acta Cirúrgica Brasileira (Online)
collection Acta Cirúrgica Brasileira (Online)
repository.name.fl_str_mv Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
repository.mail.fl_str_mv ||sgolden@terra.com.br
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