Performance evaluation of nebulizers based on aerodynamic droplet diameter characterization using the Direct Laminar Incidence (DLI)
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Research on Biomedical Engineering (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2446-47402017000200105 |
Resumo: | Abstract Introduction Optical microscope images can be useful to evaluate nebulizers considering the size of droplets produced by these devices. From this perspective, the proposed method was compared to the classic concept of Mass Median Aerodynamic Diameter (MMAD) for the ideal droplet size between 0.5-5.5 µm. Methods We tested a sample of five home nebulizers sold on the Brazilian market. A high-speed camera coupled to a microscope obtained images of the droplets during the nebulization process, which allowed us to characterize the diameter of the aero-dispersed droplets. The Count Median Aerodynamic Diameter (CMAD) was used as measurement parameter. Results The images obtained during the nebulization process with the five different nebulizers provided data to determine the frequency distribution of the aero-dispersed droplet population. Successive images were obtained in the range of 2.0s to evaluate the dynamic behavior of the droplets. The generated data also allowed the elaboration of histograms emphasizing the ideal diameter range of droplets between 0.5 and 5.5 μm. Conclusion The Direct Laminar Incidence (DLI) model using digital image processing technique allowed the characterization of respirable particles. This model proposes the creation of a range of optimum absorption of the droplets by the respiratory tract. Although there is a technical limitation in the direct acquisition of images due to the depth of focus, presenting an error of 9.3%, the described method provides consistent results when compared to other droplets characterization techniques. Thus, the authors believe that Direct Laminar Incidence (DLI) is a viable method to assess the performance of nebulizers despite the requirement of adjustments and possible improvements required to minimize measurement errors. |
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Performance evaluation of nebulizers based on aerodynamic droplet diameter characterization using the Direct Laminar Incidence (DLI)DropletsNebulizersDirect laminar incidenceAbstract Introduction Optical microscope images can be useful to evaluate nebulizers considering the size of droplets produced by these devices. From this perspective, the proposed method was compared to the classic concept of Mass Median Aerodynamic Diameter (MMAD) for the ideal droplet size between 0.5-5.5 µm. Methods We tested a sample of five home nebulizers sold on the Brazilian market. A high-speed camera coupled to a microscope obtained images of the droplets during the nebulization process, which allowed us to characterize the diameter of the aero-dispersed droplets. The Count Median Aerodynamic Diameter (CMAD) was used as measurement parameter. Results The images obtained during the nebulization process with the five different nebulizers provided data to determine the frequency distribution of the aero-dispersed droplet population. Successive images were obtained in the range of 2.0s to evaluate the dynamic behavior of the droplets. The generated data also allowed the elaboration of histograms emphasizing the ideal diameter range of droplets between 0.5 and 5.5 μm. Conclusion The Direct Laminar Incidence (DLI) model using digital image processing technique allowed the characterization of respirable particles. This model proposes the creation of a range of optimum absorption of the droplets by the respiratory tract. Although there is a technical limitation in the direct acquisition of images due to the depth of focus, presenting an error of 9.3%, the described method provides consistent results when compared to other droplets characterization techniques. Thus, the authors believe that Direct Laminar Incidence (DLI) is a viable method to assess the performance of nebulizers despite the requirement of adjustments and possible improvements required to minimize measurement errors.Sociedade Brasileira de Engenharia Biomédica2017-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2446-47402017000200105Research on Biomedical Engineering v.33 n.2 2017reponame:Research on Biomedical Engineering (Online)instname:Sociedade Brasileira de Engenharia Biomédica (SBEB)instacron:SBEB10.1590/2446-4740.05316info:eu-repo/semantics/openAccessAraújo,Luciana Martins Pereira deAbatti,Paulo JoséAraújo Filho,Walter Duarte deAlves,Rafael Fabrícioeng2017-07-21T00:00:00Zoai:scielo:S2446-47402017000200105Revistahttp://www.rbejournal.org/https://old.scielo.br/oai/scielo-oai.php||rbe@rbejournal.org2446-47402446-4732opendoar:2017-07-21T00:00Research on Biomedical Engineering (Online) - Sociedade Brasileira de Engenharia Biomédica (SBEB)false |
dc.title.none.fl_str_mv |
Performance evaluation of nebulizers based on aerodynamic droplet diameter characterization using the Direct Laminar Incidence (DLI) |
title |
Performance evaluation of nebulizers based on aerodynamic droplet diameter characterization using the Direct Laminar Incidence (DLI) |
spellingShingle |
Performance evaluation of nebulizers based on aerodynamic droplet diameter characterization using the Direct Laminar Incidence (DLI) Araújo,Luciana Martins Pereira de Droplets Nebulizers Direct laminar incidence |
title_short |
Performance evaluation of nebulizers based on aerodynamic droplet diameter characterization using the Direct Laminar Incidence (DLI) |
title_full |
Performance evaluation of nebulizers based on aerodynamic droplet diameter characterization using the Direct Laminar Incidence (DLI) |
title_fullStr |
Performance evaluation of nebulizers based on aerodynamic droplet diameter characterization using the Direct Laminar Incidence (DLI) |
title_full_unstemmed |
Performance evaluation of nebulizers based on aerodynamic droplet diameter characterization using the Direct Laminar Incidence (DLI) |
title_sort |
Performance evaluation of nebulizers based on aerodynamic droplet diameter characterization using the Direct Laminar Incidence (DLI) |
author |
Araújo,Luciana Martins Pereira de |
author_facet |
Araújo,Luciana Martins Pereira de Abatti,Paulo José Araújo Filho,Walter Duarte de Alves,Rafael Fabrício |
author_role |
author |
author2 |
Abatti,Paulo José Araújo Filho,Walter Duarte de Alves,Rafael Fabrício |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Araújo,Luciana Martins Pereira de Abatti,Paulo José Araújo Filho,Walter Duarte de Alves,Rafael Fabrício |
dc.subject.por.fl_str_mv |
Droplets Nebulizers Direct laminar incidence |
topic |
Droplets Nebulizers Direct laminar incidence |
description |
Abstract Introduction Optical microscope images can be useful to evaluate nebulizers considering the size of droplets produced by these devices. From this perspective, the proposed method was compared to the classic concept of Mass Median Aerodynamic Diameter (MMAD) for the ideal droplet size between 0.5-5.5 µm. Methods We tested a sample of five home nebulizers sold on the Brazilian market. A high-speed camera coupled to a microscope obtained images of the droplets during the nebulization process, which allowed us to characterize the diameter of the aero-dispersed droplets. The Count Median Aerodynamic Diameter (CMAD) was used as measurement parameter. Results The images obtained during the nebulization process with the five different nebulizers provided data to determine the frequency distribution of the aero-dispersed droplet population. Successive images were obtained in the range of 2.0s to evaluate the dynamic behavior of the droplets. The generated data also allowed the elaboration of histograms emphasizing the ideal diameter range of droplets between 0.5 and 5.5 μm. Conclusion The Direct Laminar Incidence (DLI) model using digital image processing technique allowed the characterization of respirable particles. This model proposes the creation of a range of optimum absorption of the droplets by the respiratory tract. Although there is a technical limitation in the direct acquisition of images due to the depth of focus, presenting an error of 9.3%, the described method provides consistent results when compared to other droplets characterization techniques. Thus, the authors believe that Direct Laminar Incidence (DLI) is a viable method to assess the performance of nebulizers despite the requirement of adjustments and possible improvements required to minimize measurement errors. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2446-47402017000200105 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2446-47402017000200105 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/2446-4740.05316 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Engenharia Biomédica |
publisher.none.fl_str_mv |
Sociedade Brasileira de Engenharia Biomédica |
dc.source.none.fl_str_mv |
Research on Biomedical Engineering v.33 n.2 2017 reponame:Research on Biomedical Engineering (Online) instname:Sociedade Brasileira de Engenharia Biomédica (SBEB) instacron:SBEB |
instname_str |
Sociedade Brasileira de Engenharia Biomédica (SBEB) |
instacron_str |
SBEB |
institution |
SBEB |
reponame_str |
Research on Biomedical Engineering (Online) |
collection |
Research on Biomedical Engineering (Online) |
repository.name.fl_str_mv |
Research on Biomedical Engineering (Online) - Sociedade Brasileira de Engenharia Biomédica (SBEB) |
repository.mail.fl_str_mv |
||rbe@rbejournal.org |
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1752126288738385920 |