Association between atypical parathyroid adenoma and neurofibromatosis

• Main Author: Favere,Aline Mesquita Ferreira de
• Publication Date: 2015
• Other Authors: Tsukumo,Daniela Miti, Matos,Patrícia Sabino de, Santos,Sérgio Luiz Marques dos, Lalli,Cristina Alba
• Format: Report
• Language: eng
• Source: Arquivos de Endocrinologia e Metabolismo (Online)
• Download full: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972015000500460

Primary hyperparathyroidism is a disease characterized by excessive production of parathyroid hormone (PTH), which is due to a parathyroid adenoma in 85% of cases. An atypical parathyroid adenoma, with some histopathological features of parathyroid carcinoma, may be found in some of the cases, although it may not fulfill all the criteria for this diagnosis. Neurofibromatosis type 1 (NF1) is an autosomal dominant systemic disease that may be associated with hyperparathyroidism. We report here the rare combination of a patient with NF1 and clinical manifestations of hyperparathyroidism due to an atypical parathyroid adenoma.