Detalhes bibliográficos
| Autor(a) principal: |
Clapauch,Ruth |
| Data de Publicação: |
2008 |
| Outros Autores: |
Carmo,Aline Machado,
Marinheiro,Lizanka,
Buksman,Salo,
Pessoa,Isabel |
| Tipo de documento: |
Artigo
|
| Idioma: |
eng |
| Título da fonte: |
Arquivos Brasileiros de Endocrinologia & Metabologia (Online) |
| Texto Completo: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302008000900005
|
Resumo: |
OBJECTIVES: To evaluate which factors influence the laboratorial diagnosis of late-onset male hypogonadism (LOH). METHODS: Total testosterone (TT), SHBG and albumin were measured in 216 men aged 52-84 years. The laboratorial definition of LOH was two values of calculated free testosterone (cFT) <6.5 ng/dl, according to Vermeulen's formula. RESULTS: At the first blood test, cFT was <6.5 ng/dl in 27% of the men. Laboratorial LOH (confirmed by two tests) was present in 19%, but TT levels were low in only 4.1%. Age influenced TT (p=0.0051) as well as BMI; 23.5% of patients > 70 years and 38.9% of the obese men who had TT within the reference range were, in fact, hypogonadal. CONCLUSION: Especially in obese men and in those > 70 years old, SHBG dosage is important to calculate FT levels and diagnose hypogonadism. |