Pediatric Cushing's syndrome: clinical features, diagnosis, and treatment
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos Brasileiros de Endocrinologia & Metabologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302007000800012 |
Resumo: | Cushing's syndrome (CS) results from prolonged exposure to supraphysiological levels of circulating glucocorticoids, endogenously or exogenously derived. Although rare in childhood, CS remains a difficult condition to diagnose and treat. A multidisciplinary approach and close collaboration with adult colleagues is adopted at most large centres that manage pediatric CS patients. Although pediatric protocols are derived from adult data, significant differences exist between adult and childhood CS. Furthermore, long term outcome parameters including final height, bone mineral density, reproductive function, body composition and psychological health pose challenges for pediatric care. This article will aim to provide an overall view of pediatric CS highlighting some of the differences between adult and pediatric CS. |
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Pediatric Cushing's syndrome: clinical features, diagnosis, and treatmentPediatricsCushing's syndromeCushing's diseaseAdrenal tumoursCushing's syndrome (CS) results from prolonged exposure to supraphysiological levels of circulating glucocorticoids, endogenously or exogenously derived. Although rare in childhood, CS remains a difficult condition to diagnose and treat. A multidisciplinary approach and close collaboration with adult colleagues is adopted at most large centres that manage pediatric CS patients. Although pediatric protocols are derived from adult data, significant differences exist between adult and childhood CS. Furthermore, long term outcome parameters including final height, bone mineral density, reproductive function, body composition and psychological health pose challenges for pediatric care. This article will aim to provide an overall view of pediatric CS highlighting some of the differences between adult and pediatric CS.Sociedade Brasileira de Endocrinologia e Metabologia2007-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302007000800012Arquivos Brasileiros de Endocrinologia & Metabologia v.51 n.8 2007reponame:Arquivos Brasileiros de Endocrinologia & Metabologia (Online)instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)instacron:SBEM10.1590/S0004-27302007000800012info:eu-repo/semantics/openAccessChan,Li F.Storr,Helen L.Grossman,Ashley B.Savage,Martin O.eng2008-01-14T00:00:00Zoai:scielo:S0004-27302007000800012Revistahttps://www.aem-sbem.com/ONGhttps://old.scielo.br/oai/scielo-oai.php||abem-editoria@endocrino.org.br1677-94870004-2730opendoar:2008-01-14T00:00Arquivos Brasileiros de Endocrinologia & Metabologia (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)false |
dc.title.none.fl_str_mv |
Pediatric Cushing's syndrome: clinical features, diagnosis, and treatment |
title |
Pediatric Cushing's syndrome: clinical features, diagnosis, and treatment |
spellingShingle |
Pediatric Cushing's syndrome: clinical features, diagnosis, and treatment Chan,Li F. Pediatrics Cushing's syndrome Cushing's disease Adrenal tumours |
title_short |
Pediatric Cushing's syndrome: clinical features, diagnosis, and treatment |
title_full |
Pediatric Cushing's syndrome: clinical features, diagnosis, and treatment |
title_fullStr |
Pediatric Cushing's syndrome: clinical features, diagnosis, and treatment |
title_full_unstemmed |
Pediatric Cushing's syndrome: clinical features, diagnosis, and treatment |
title_sort |
Pediatric Cushing's syndrome: clinical features, diagnosis, and treatment |
author |
Chan,Li F. |
author_facet |
Chan,Li F. Storr,Helen L. Grossman,Ashley B. Savage,Martin O. |
author_role |
author |
author2 |
Storr,Helen L. Grossman,Ashley B. Savage,Martin O. |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Chan,Li F. Storr,Helen L. Grossman,Ashley B. Savage,Martin O. |
dc.subject.por.fl_str_mv |
Pediatrics Cushing's syndrome Cushing's disease Adrenal tumours |
topic |
Pediatrics Cushing's syndrome Cushing's disease Adrenal tumours |
description |
Cushing's syndrome (CS) results from prolonged exposure to supraphysiological levels of circulating glucocorticoids, endogenously or exogenously derived. Although rare in childhood, CS remains a difficult condition to diagnose and treat. A multidisciplinary approach and close collaboration with adult colleagues is adopted at most large centres that manage pediatric CS patients. Although pediatric protocols are derived from adult data, significant differences exist between adult and childhood CS. Furthermore, long term outcome parameters including final height, bone mineral density, reproductive function, body composition and psychological health pose challenges for pediatric care. This article will aim to provide an overall view of pediatric CS highlighting some of the differences between adult and pediatric CS. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-11-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302007000800012 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302007000800012 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-27302007000800012 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Endocrinologia e Metabologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Endocrinologia e Metabologia |
dc.source.none.fl_str_mv |
Arquivos Brasileiros de Endocrinologia & Metabologia v.51 n.8 2007 reponame:Arquivos Brasileiros de Endocrinologia & Metabologia (Online) instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) instacron:SBEM |
instname_str |
Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) |
instacron_str |
SBEM |
institution |
SBEM |
reponame_str |
Arquivos Brasileiros de Endocrinologia & Metabologia (Online) |
collection |
Arquivos Brasileiros de Endocrinologia & Metabologia (Online) |
repository.name.fl_str_mv |
Arquivos Brasileiros de Endocrinologia & Metabologia (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) |
repository.mail.fl_str_mv |
||abem-editoria@endocrino.org.br |
_version_ |
1754734809327861760 |