HIV infection, bone metabolism, and fractures

Detalhes bibliográficos
Autor(a) principal: Güerri-Fernández,Robert
Data de Publicação: 2014
Outros Autores: Villar-García,Judit, Díez-Pérez,Adolfo, Prieto-Alhambra,Daniel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302014000500478
Resumo: With the advent of high active antiretroviral therapy there was a significant improvement on HIV subjects survival. Thus, bone changes related to HIV became an important aspect of these individuals. HIV affects bone remodeling causing bone fragility. In addition, antiretroviral therapy may also negatively affect bone metabolism. Several studies describe an increased incidence of fractures in these patients when compared with controls without the disease. The European Society of AIDS (EACS), and other societies, have included guidance on management of osteoporosis in HIV-infected patients emphasizing the identification of patients with low bone mass. Supplementation of calcium and vitamin D and the use of alendronate in these individuals should be recommended on a case base.
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spelling HIV infection, bone metabolism, and fracturesBonebone metabolismHIVbone fracturesWith the advent of high active antiretroviral therapy there was a significant improvement on HIV subjects survival. Thus, bone changes related to HIV became an important aspect of these individuals. HIV affects bone remodeling causing bone fragility. In addition, antiretroviral therapy may also negatively affect bone metabolism. Several studies describe an increased incidence of fractures in these patients when compared with controls without the disease. The European Society of AIDS (EACS), and other societies, have included guidance on management of osteoporosis in HIV-infected patients emphasizing the identification of patients with low bone mass. Supplementation of calcium and vitamin D and the use of alendronate in these individuals should be recommended on a case base.Sociedade Brasileira de Endocrinologia e Metabologia2014-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302014000500478Arquivos Brasileiros de Endocrinologia & Metabologia v.58 n.5 2014reponame:Arquivos Brasileiros de Endocrinologia & Metabologia (Online)instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)instacron:SBEM10.1590/0004-2730000003323info:eu-repo/semantics/openAccessGüerri-Fernández,RobertVillar-García,JuditDíez-Pérez,AdolfoPrieto-Alhambra,Danieleng2014-08-19T00:00:00Zoai:scielo:S0004-27302014000500478Revistahttps://www.aem-sbem.com/ONGhttps://old.scielo.br/oai/scielo-oai.php||abem-editoria@endocrino.org.br1677-94870004-2730opendoar:2014-08-19T00:00Arquivos Brasileiros de Endocrinologia & Metabologia (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)false
dc.title.none.fl_str_mv HIV infection, bone metabolism, and fractures
title HIV infection, bone metabolism, and fractures
spellingShingle HIV infection, bone metabolism, and fractures
Güerri-Fernández,Robert
Bone
bone metabolism
HIV
bone fractures
title_short HIV infection, bone metabolism, and fractures
title_full HIV infection, bone metabolism, and fractures
title_fullStr HIV infection, bone metabolism, and fractures
title_full_unstemmed HIV infection, bone metabolism, and fractures
title_sort HIV infection, bone metabolism, and fractures
author Güerri-Fernández,Robert
author_facet Güerri-Fernández,Robert
Villar-García,Judit
Díez-Pérez,Adolfo
Prieto-Alhambra,Daniel
author_role author
author2 Villar-García,Judit
Díez-Pérez,Adolfo
Prieto-Alhambra,Daniel
author2_role author
author
author
dc.contributor.author.fl_str_mv Güerri-Fernández,Robert
Villar-García,Judit
Díez-Pérez,Adolfo
Prieto-Alhambra,Daniel
dc.subject.por.fl_str_mv Bone
bone metabolism
HIV
bone fractures
topic Bone
bone metabolism
HIV
bone fractures
description With the advent of high active antiretroviral therapy there was a significant improvement on HIV subjects survival. Thus, bone changes related to HIV became an important aspect of these individuals. HIV affects bone remodeling causing bone fragility. In addition, antiretroviral therapy may also negatively affect bone metabolism. Several studies describe an increased incidence of fractures in these patients when compared with controls without the disease. The European Society of AIDS (EACS), and other societies, have included guidance on management of osteoporosis in HIV-infected patients emphasizing the identification of patients with low bone mass. Supplementation of calcium and vitamin D and the use of alendronate in these individuals should be recommended on a case base.
publishDate 2014
dc.date.none.fl_str_mv 2014-07-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302014000500478
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302014000500478
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0004-2730000003323
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Endocrinologia e Metabologia
publisher.none.fl_str_mv Sociedade Brasileira de Endocrinologia e Metabologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Endocrinologia & Metabologia v.58 n.5 2014
reponame:Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
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instname_str Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
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institution SBEM
reponame_str Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
collection Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
repository.name.fl_str_mv Arquivos Brasileiros de Endocrinologia & Metabologia (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
repository.mail.fl_str_mv ||abem-editoria@endocrino.org.br
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