Antinociceptive activity of Ipomoea imperati (Vahl) Griseb., Convolvulaceae

Detalhes bibliográficos
Autor(a) principal: Paula-Zurron,Ana Claudia B. De
Data de Publicação: 2010
Outros Autores: Petraglia,Nilva M. M. A., Aur,Carlos R., Moura,Sérgio H. P., Imamura,Paulo M., Freitas,José C. De, Catanzaro-Guimarães,Sérgio A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2010000200008
Resumo: Ipomoea imperati (Vahl) Griseb., Convolvulaceae, is used in folk medicine for the treatment of inflammation, swelling and wounds, as well as to treat pains after childbirth and for stomach problems. Administration of ethanol extract, lipid and aqueous fraction of I. imperati(300, 100 and 200 mg/kg) significantly inhibited the abdominal constriction in mice induced by acetic acid; increased the sleeping time evoked by pentobarbital sodium and showed a significant activity by inhibiting formalin-induced paw edema in mice. The same dose of I. imperatialso raised the pain of mice in the hot-plate test and increased the latency at all observation times. The pre-treatment of the animals with naloxone (5 mg/kg, i.p.) suggested the participation of the opioid system in the antinociceptive effect of Ipomoea imperati.
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spelling Antinociceptive activity of Ipomoea imperati (Vahl) Griseb., ConvolvulaceaeIpomoea imperatiConvolvulaceaepainanalgesic activityopioid systemIpomoea imperati (Vahl) Griseb., Convolvulaceae, is used in folk medicine for the treatment of inflammation, swelling and wounds, as well as to treat pains after childbirth and for stomach problems. Administration of ethanol extract, lipid and aqueous fraction of I. imperati(300, 100 and 200 mg/kg) significantly inhibited the abdominal constriction in mice induced by acetic acid; increased the sleeping time evoked by pentobarbital sodium and showed a significant activity by inhibiting formalin-induced paw edema in mice. The same dose of I. imperatialso raised the pain of mice in the hot-plate test and increased the latency at all observation times. The pre-treatment of the animals with naloxone (5 mg/kg, i.p.) suggested the participation of the opioid system in the antinociceptive effect of Ipomoea imperati.Sociedade Brasileira de Farmacognosia2010-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2010000200008Revista Brasileira de Farmacognosia v.20 n.2 2010reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2010000200008info:eu-repo/semantics/openAccessPaula-Zurron,Ana Claudia B. DePetraglia,Nilva M. M. A.Aur,Carlos R.Moura,Sérgio H. P.Imamura,Paulo M.Freitas,José C. DeCatanzaro-Guimarães,Sérgio A.eng2010-06-11T00:00:00Zoai:scielo:S0102-695X2010000200008Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2010-06-11T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Antinociceptive activity of Ipomoea imperati (Vahl) Griseb., Convolvulaceae
title Antinociceptive activity of Ipomoea imperati (Vahl) Griseb., Convolvulaceae
spellingShingle Antinociceptive activity of Ipomoea imperati (Vahl) Griseb., Convolvulaceae
Paula-Zurron,Ana Claudia B. De
Ipomoea imperati
Convolvulaceae
pain
analgesic activity
opioid system
title_short Antinociceptive activity of Ipomoea imperati (Vahl) Griseb., Convolvulaceae
title_full Antinociceptive activity of Ipomoea imperati (Vahl) Griseb., Convolvulaceae
title_fullStr Antinociceptive activity of Ipomoea imperati (Vahl) Griseb., Convolvulaceae
title_full_unstemmed Antinociceptive activity of Ipomoea imperati (Vahl) Griseb., Convolvulaceae
title_sort Antinociceptive activity of Ipomoea imperati (Vahl) Griseb., Convolvulaceae
author Paula-Zurron,Ana Claudia B. De
author_facet Paula-Zurron,Ana Claudia B. De
Petraglia,Nilva M. M. A.
Aur,Carlos R.
Moura,Sérgio H. P.
Imamura,Paulo M.
Freitas,José C. De
Catanzaro-Guimarães,Sérgio A.
author_role author
author2 Petraglia,Nilva M. M. A.
Aur,Carlos R.
Moura,Sérgio H. P.
Imamura,Paulo M.
Freitas,José C. De
Catanzaro-Guimarães,Sérgio A.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Paula-Zurron,Ana Claudia B. De
Petraglia,Nilva M. M. A.
Aur,Carlos R.
Moura,Sérgio H. P.
Imamura,Paulo M.
Freitas,José C. De
Catanzaro-Guimarães,Sérgio A.
dc.subject.por.fl_str_mv Ipomoea imperati
Convolvulaceae
pain
analgesic activity
opioid system
topic Ipomoea imperati
Convolvulaceae
pain
analgesic activity
opioid system
description Ipomoea imperati (Vahl) Griseb., Convolvulaceae, is used in folk medicine for the treatment of inflammation, swelling and wounds, as well as to treat pains after childbirth and for stomach problems. Administration of ethanol extract, lipid and aqueous fraction of I. imperati(300, 100 and 200 mg/kg) significantly inhibited the abdominal constriction in mice induced by acetic acid; increased the sleeping time evoked by pentobarbital sodium and showed a significant activity by inhibiting formalin-induced paw edema in mice. The same dose of I. imperatialso raised the pain of mice in the hot-plate test and increased the latency at all observation times. The pre-treatment of the animals with naloxone (5 mg/kg, i.p.) suggested the participation of the opioid system in the antinociceptive effect of Ipomoea imperati.
publishDate 2010
dc.date.none.fl_str_mv 2010-05-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2010000200008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2010000200008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2010000200008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.20 n.2 2010
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
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reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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