Development and validation of a HPLC method for standardization of herbal and commercial extracts of Myrcia uniflora

Detalhes bibliográficos
Autor(a) principal: Batista,Andrea N. de L.
Data de Publicação: 2011
Outros Autores: Colombo,Renata, Pascoli,Inara C. de, Teles,Helder L., Silva,Geraldo H., Bomfim,Giovanni C. C., Burgos,Rosilene C. R., Cavalheiro,Alberto J., Bolzani,Vanderlan da Silva, Silva,Dulce H. S., Reimberg,Maria Célia H.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000300008
Resumo: Myrcia uniflora Barb. Rodr., Myrtaceae, popularly known as "pedra-hume-caá" in Brazil, is sold as dry extracts in capsules or as tinctures for the treatment of diabetes mellitus. Previous phytochemical studies on this species described the occurrence of the flavonoids mearnsitrin and myricitrin. In the present study, the chromatographic profiles of M. uniflora leaves and commercial extracts were determined using HPLC-PAD. Myricitrin was used as an external standard in the development and validation of the HPLC method. The proposed method is simple, rapid and reliable and can be successfully applied in industry for standardization of herbs and phytomedicines commercialised in Brazil as "pedra-hume-caá".
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spelling Development and validation of a HPLC method for standardization of herbal and commercial extracts of Myrcia unifloraMyrcia uniflorapedra-hume-caáHPLCmyricitrinstandardizationMyrcia uniflora Barb. Rodr., Myrtaceae, popularly known as "pedra-hume-caá" in Brazil, is sold as dry extracts in capsules or as tinctures for the treatment of diabetes mellitus. Previous phytochemical studies on this species described the occurrence of the flavonoids mearnsitrin and myricitrin. In the present study, the chromatographic profiles of M. uniflora leaves and commercial extracts were determined using HPLC-PAD. Myricitrin was used as an external standard in the development and validation of the HPLC method. The proposed method is simple, rapid and reliable and can be successfully applied in industry for standardization of herbs and phytomedicines commercialised in Brazil as "pedra-hume-caá".Sociedade Brasileira de Farmacognosia2011-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000300008Revista Brasileira de Farmacognosia v.21 n.3 2011reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2011005000066info:eu-repo/semantics/openAccessBatista,Andrea N. de L.Colombo,RenataPascoli,Inara C. deTeles,Helder L.Silva,Geraldo H.Bomfim,Giovanni C. C.Burgos,Rosilene C. R.Cavalheiro,Alberto J.Bolzani,Vanderlan da SilvaSilva,Dulce H. S.Reimberg,Maria Célia H.eng2011-07-08T00:00:00Zoai:scielo:S0102-695X2011000300008Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2011-07-08T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Development and validation of a HPLC method for standardization of herbal and commercial extracts of Myrcia uniflora
title Development and validation of a HPLC method for standardization of herbal and commercial extracts of Myrcia uniflora
spellingShingle Development and validation of a HPLC method for standardization of herbal and commercial extracts of Myrcia uniflora
Batista,Andrea N. de L.
Myrcia uniflora
pedra-hume-caá
HPLC
myricitrin
standardization
title_short Development and validation of a HPLC method for standardization of herbal and commercial extracts of Myrcia uniflora
title_full Development and validation of a HPLC method for standardization of herbal and commercial extracts of Myrcia uniflora
title_fullStr Development and validation of a HPLC method for standardization of herbal and commercial extracts of Myrcia uniflora
title_full_unstemmed Development and validation of a HPLC method for standardization of herbal and commercial extracts of Myrcia uniflora
title_sort Development and validation of a HPLC method for standardization of herbal and commercial extracts of Myrcia uniflora
author Batista,Andrea N. de L.
author_facet Batista,Andrea N. de L.
Colombo,Renata
Pascoli,Inara C. de
Teles,Helder L.
Silva,Geraldo H.
Bomfim,Giovanni C. C.
Burgos,Rosilene C. R.
Cavalheiro,Alberto J.
Bolzani,Vanderlan da Silva
Silva,Dulce H. S.
Reimberg,Maria Célia H.
author_role author
author2 Colombo,Renata
Pascoli,Inara C. de
Teles,Helder L.
Silva,Geraldo H.
Bomfim,Giovanni C. C.
Burgos,Rosilene C. R.
Cavalheiro,Alberto J.
Bolzani,Vanderlan da Silva
Silva,Dulce H. S.
Reimberg,Maria Célia H.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Batista,Andrea N. de L.
Colombo,Renata
Pascoli,Inara C. de
Teles,Helder L.
Silva,Geraldo H.
Bomfim,Giovanni C. C.
Burgos,Rosilene C. R.
Cavalheiro,Alberto J.
Bolzani,Vanderlan da Silva
Silva,Dulce H. S.
Reimberg,Maria Célia H.
dc.subject.por.fl_str_mv Myrcia uniflora
pedra-hume-caá
HPLC
myricitrin
standardization
topic Myrcia uniflora
pedra-hume-caá
HPLC
myricitrin
standardization
description Myrcia uniflora Barb. Rodr., Myrtaceae, popularly known as "pedra-hume-caá" in Brazil, is sold as dry extracts in capsules or as tinctures for the treatment of diabetes mellitus. Previous phytochemical studies on this species described the occurrence of the flavonoids mearnsitrin and myricitrin. In the present study, the chromatographic profiles of M. uniflora leaves and commercial extracts were determined using HPLC-PAD. Myricitrin was used as an external standard in the development and validation of the HPLC method. The proposed method is simple, rapid and reliable and can be successfully applied in industry for standardization of herbs and phytomedicines commercialised in Brazil as "pedra-hume-caá".
publishDate 2011
dc.date.none.fl_str_mv 2011-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000300008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000300008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2011005000066
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.21 n.3 2011
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
institution SBFGNOSIA
reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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