Investigation of protective effects of Erythrina velutina extract against MMS induced damages in the root meristem cells of Allium cepa
Autor(a) principal: | |
---|---|
Data de Publicação: | 2013 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Farmacognosia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2013000200011 |
Resumo: | Erythrina velutina Willd., Fabaceae, is a medicinal plant that can be found in the tropics and subtropics, including in the semi-arid northeastern Brazil. It is commonly used in folk medicine to treat anxiety, agitation and insomnia. E. velutina has been known to present analgesic, anti-inflammatory and antibacterial activities, however, it is unknown if this plant present a protective effect on DNA. We assessed the antigenotoxic effect of E. velutina against the genotoxic effects induced by MMS in the root meristem cells of Allium cepa. Three concentrations of the aqueous extract (100, 200 and 400 mg/L) of this medicinal plant were used in three different types of treatment (pre-, post- and simultaneous). The effects of the extracts on the root meristem cells of A. cepa were analyzed at both macroscopic and microscopic levels. Protective effects were observed at higher concentrations in pre-treatment and in simultaneous treatment. The results suggest that E. velutina may present antigenotoxic properties and demonstrate its chemopreventive potential. |
id |
SBFGNOSIA-1_84b0fb348f2c77285c7cd58a5db2ed7e |
---|---|
oai_identifier_str |
oai:scielo:S0102-695X2013000200011 |
network_acronym_str |
SBFGNOSIA-1 |
network_name_str |
Revista Brasileira de Farmacognosia (Online) |
repository_id_str |
|
spelling |
Investigation of protective effects of Erythrina velutina extract against MMS induced damages in the root meristem cells of Allium cepaAllium cepaantigenotoxicitychromosomal aberrationErythrina velutinaFabaceaeroot growthErythrina velutina Willd., Fabaceae, is a medicinal plant that can be found in the tropics and subtropics, including in the semi-arid northeastern Brazil. It is commonly used in folk medicine to treat anxiety, agitation and insomnia. E. velutina has been known to present analgesic, anti-inflammatory and antibacterial activities, however, it is unknown if this plant present a protective effect on DNA. We assessed the antigenotoxic effect of E. velutina against the genotoxic effects induced by MMS in the root meristem cells of Allium cepa. Three concentrations of the aqueous extract (100, 200 and 400 mg/L) of this medicinal plant were used in three different types of treatment (pre-, post- and simultaneous). The effects of the extracts on the root meristem cells of A. cepa were analyzed at both macroscopic and microscopic levels. Protective effects were observed at higher concentrations in pre-treatment and in simultaneous treatment. The results suggest that E. velutina may present antigenotoxic properties and demonstrate its chemopreventive potential.Sociedade Brasileira de Farmacognosia2013-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2013000200011Revista Brasileira de Farmacognosia v.23 n.2 2013reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2013005000006info:eu-repo/semantics/openAccessSilva,Deborah S. B. S.Barboza,BenhurGarcia,Anuska C. F. S.Oliveira,Betejane deEstevam,Charles S.A. Neto,VitorSantos,Andre L. L. M.Dias,Antonio S.Scher,RicardoPantaleao,Silmara M.eng2013-03-27T00:00:00Zoai:scielo:S0102-695X2013000200011Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2013-03-27T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false |
dc.title.none.fl_str_mv |
Investigation of protective effects of Erythrina velutina extract against MMS induced damages in the root meristem cells of Allium cepa |
title |
Investigation of protective effects of Erythrina velutina extract against MMS induced damages in the root meristem cells of Allium cepa |
spellingShingle |
Investigation of protective effects of Erythrina velutina extract against MMS induced damages in the root meristem cells of Allium cepa Silva,Deborah S. B. S. Allium cepa antigenotoxicity chromosomal aberration Erythrina velutina Fabaceae root growth |
title_short |
Investigation of protective effects of Erythrina velutina extract against MMS induced damages in the root meristem cells of Allium cepa |
title_full |
Investigation of protective effects of Erythrina velutina extract against MMS induced damages in the root meristem cells of Allium cepa |
title_fullStr |
Investigation of protective effects of Erythrina velutina extract against MMS induced damages in the root meristem cells of Allium cepa |
title_full_unstemmed |
Investigation of protective effects of Erythrina velutina extract against MMS induced damages in the root meristem cells of Allium cepa |
title_sort |
Investigation of protective effects of Erythrina velutina extract against MMS induced damages in the root meristem cells of Allium cepa |
author |
Silva,Deborah S. B. S. |
author_facet |
Silva,Deborah S. B. S. Barboza,Benhur Garcia,Anuska C. F. S. Oliveira,Betejane de Estevam,Charles S. A. Neto,Vitor Santos,Andre L. L. M. Dias,Antonio S. Scher,Ricardo Pantaleao,Silmara M. |
author_role |
author |
author2 |
Barboza,Benhur Garcia,Anuska C. F. S. Oliveira,Betejane de Estevam,Charles S. A. Neto,Vitor Santos,Andre L. L. M. Dias,Antonio S. Scher,Ricardo Pantaleao,Silmara M. |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Silva,Deborah S. B. S. Barboza,Benhur Garcia,Anuska C. F. S. Oliveira,Betejane de Estevam,Charles S. A. Neto,Vitor Santos,Andre L. L. M. Dias,Antonio S. Scher,Ricardo Pantaleao,Silmara M. |
dc.subject.por.fl_str_mv |
Allium cepa antigenotoxicity chromosomal aberration Erythrina velutina Fabaceae root growth |
topic |
Allium cepa antigenotoxicity chromosomal aberration Erythrina velutina Fabaceae root growth |
description |
Erythrina velutina Willd., Fabaceae, is a medicinal plant that can be found in the tropics and subtropics, including in the semi-arid northeastern Brazil. It is commonly used in folk medicine to treat anxiety, agitation and insomnia. E. velutina has been known to present analgesic, anti-inflammatory and antibacterial activities, however, it is unknown if this plant present a protective effect on DNA. We assessed the antigenotoxic effect of E. velutina against the genotoxic effects induced by MMS in the root meristem cells of Allium cepa. Three concentrations of the aqueous extract (100, 200 and 400 mg/L) of this medicinal plant were used in three different types of treatment (pre-, post- and simultaneous). The effects of the extracts on the root meristem cells of A. cepa were analyzed at both macroscopic and microscopic levels. Protective effects were observed at higher concentrations in pre-treatment and in simultaneous treatment. The results suggest that E. velutina may present antigenotoxic properties and demonstrate its chemopreventive potential. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2013000200011 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2013000200011 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0102-695X2013005000006 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
dc.source.none.fl_str_mv |
Revista Brasileira de Farmacognosia v.23 n.2 2013 reponame:Revista Brasileira de Farmacognosia (Online) instname:Sociedade Brasileira de Farmacognosia (SBFgnosia) instacron:SBFGNOSIA |
instname_str |
Sociedade Brasileira de Farmacognosia (SBFgnosia) |
instacron_str |
SBFGNOSIA |
institution |
SBFGNOSIA |
reponame_str |
Revista Brasileira de Farmacognosia (Online) |
collection |
Revista Brasileira de Farmacognosia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia) |
repository.mail.fl_str_mv |
rbgnosia@ltf.ufpb.br |
_version_ |
1752122468705763328 |