Absence of mutagenic and citotoxic potentiality of senna (Cassia angustifolia Vahl.) evaluated by microbiological tests

Detalhes bibliográficos
Autor(a) principal: Silva,C.R
Data de Publicação: 2004
Outros Autores: Monteiro,M.R, Caldeira-de-Araújo,A., Bezerra,R.J.A.C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2004000300001
Resumo: Senna (Cassia angustifolia Vahl.) is widely used as laxative, but data from Ames test and animal and/or human studies with this agent have shown a mutagenic and carcinogenic potentiality. Using thee experimental models (bacterial inactivation test; bacterail mutagenisis assay-Mutoxitest; and growth Inhibition test, we investigated the toxicity of senna. Our data suggest an absence of mutagenic and citotoxic potentiality of senna.
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spelling Absence of mutagenic and citotoxic potentiality of senna (Cassia angustifolia Vahl.) evaluated by microbiological testsSenna (Cassia angustifolia Vahl.) is widely used as laxative, but data from Ames test and animal and/or human studies with this agent have shown a mutagenic and carcinogenic potentiality. Using thee experimental models (bacterial inactivation test; bacterail mutagenisis assay-Mutoxitest; and growth Inhibition test, we investigated the toxicity of senna. Our data suggest an absence of mutagenic and citotoxic potentiality of senna.Sociedade Brasileira de Farmacognosia2004-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2004000300001Revista Brasileira de Farmacognosia v.14 suppl.0 2004reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2004000300001info:eu-repo/semantics/openAccessSilva,C.RMonteiro,M.RCaldeira-de-Araújo,A.Bezerra,R.J.A.C.eng2008-09-16T00:00:00Zoai:scielo:S0102-695X2004000300001Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2008-09-16T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Absence of mutagenic and citotoxic potentiality of senna (Cassia angustifolia Vahl.) evaluated by microbiological tests
title Absence of mutagenic and citotoxic potentiality of senna (Cassia angustifolia Vahl.) evaluated by microbiological tests
spellingShingle Absence of mutagenic and citotoxic potentiality of senna (Cassia angustifolia Vahl.) evaluated by microbiological tests
Silva,C.R
title_short Absence of mutagenic and citotoxic potentiality of senna (Cassia angustifolia Vahl.) evaluated by microbiological tests
title_full Absence of mutagenic and citotoxic potentiality of senna (Cassia angustifolia Vahl.) evaluated by microbiological tests
title_fullStr Absence of mutagenic and citotoxic potentiality of senna (Cassia angustifolia Vahl.) evaluated by microbiological tests
title_full_unstemmed Absence of mutagenic and citotoxic potentiality of senna (Cassia angustifolia Vahl.) evaluated by microbiological tests
title_sort Absence of mutagenic and citotoxic potentiality of senna (Cassia angustifolia Vahl.) evaluated by microbiological tests
author Silva,C.R
author_facet Silva,C.R
Monteiro,M.R
Caldeira-de-Araújo,A.
Bezerra,R.J.A.C.
author_role author
author2 Monteiro,M.R
Caldeira-de-Araújo,A.
Bezerra,R.J.A.C.
author2_role author
author
author
dc.contributor.author.fl_str_mv Silva,C.R
Monteiro,M.R
Caldeira-de-Araújo,A.
Bezerra,R.J.A.C.
description Senna (Cassia angustifolia Vahl.) is widely used as laxative, but data from Ames test and animal and/or human studies with this agent have shown a mutagenic and carcinogenic potentiality. Using thee experimental models (bacterial inactivation test; bacterail mutagenisis assay-Mutoxitest; and growth Inhibition test, we investigated the toxicity of senna. Our data suggest an absence of mutagenic and citotoxic potentiality of senna.
publishDate 2004
dc.date.none.fl_str_mv 2004-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2004000300001
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2004000300001
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2004000300001
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.14 suppl.0 2004
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
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collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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