Genotoxicity and cytotoxicity of Erythrina velutina Willd., Fabaceae, on the root meristem cells of Allium cepa

Detalhes bibliográficos
Autor(a) principal: Silva,Déborah S. B. S.
Data de Publicação: 2011
Outros Autores: Garcia,Anuska C. F. S., Mata,Samuel S., Oliveira,Betejane de, Estevam,Charles S., Scher,Ricardo, Pantaleao,Silmara M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000100016
Resumo: The effects of the decoction of Erythrina velutina Willd., Fabaceae, were investigated using the root meristem cells of Allium cepa L., Amaryllidaceae. Ten concentrations of the aqueous extract (0.125 to 1.25%) of this medicinal plant were analyzed at both macroscopic and microscopic levels. All concentrations showed root growth inhibition after 96 h treatment. Although there were no significant differences between the mitotic indexes of any concentration and the control, there were changes in the frequencies of cell stages at three different concentrations. Additionally, the presence of five different cells abnormalities was recorded: chromosome bridging, lagging chromosomes, chromosome fragments, disturbed metaphase and disturbed anaphase. These results suggest inhibitory and genotoxic activity of the decoction of E. velutina on Allium cepa.
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spelling Genotoxicity and cytotoxicity of Erythrina velutina Willd., Fabaceae, on the root meristem cells of Allium cepaErythrina velutinaAllium ceparoot growthmitotic indexchromosomal aberrationThe effects of the decoction of Erythrina velutina Willd., Fabaceae, were investigated using the root meristem cells of Allium cepa L., Amaryllidaceae. Ten concentrations of the aqueous extract (0.125 to 1.25%) of this medicinal plant were analyzed at both macroscopic and microscopic levels. All concentrations showed root growth inhibition after 96 h treatment. Although there were no significant differences between the mitotic indexes of any concentration and the control, there were changes in the frequencies of cell stages at three different concentrations. Additionally, the presence of five different cells abnormalities was recorded: chromosome bridging, lagging chromosomes, chromosome fragments, disturbed metaphase and disturbed anaphase. These results suggest inhibitory and genotoxic activity of the decoction of E. velutina on Allium cepa.Sociedade Brasileira de Farmacognosia2011-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000100016Revista Brasileira de Farmacognosia v.21 n.1 2011reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2011005000024info:eu-repo/semantics/openAccessSilva,Déborah S. B. S.Garcia,Anuska C. F. S.Mata,Samuel S.Oliveira,Betejane deEstevam,Charles S.Scher,RicardoPantaleao,Silmara M.eng2011-03-28T00:00:00Zoai:scielo:S0102-695X2011000100016Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2011-03-28T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Genotoxicity and cytotoxicity of Erythrina velutina Willd., Fabaceae, on the root meristem cells of Allium cepa
title Genotoxicity and cytotoxicity of Erythrina velutina Willd., Fabaceae, on the root meristem cells of Allium cepa
spellingShingle Genotoxicity and cytotoxicity of Erythrina velutina Willd., Fabaceae, on the root meristem cells of Allium cepa
Silva,Déborah S. B. S.
Erythrina velutina
Allium cepa
root growth
mitotic index
chromosomal aberration
title_short Genotoxicity and cytotoxicity of Erythrina velutina Willd., Fabaceae, on the root meristem cells of Allium cepa
title_full Genotoxicity and cytotoxicity of Erythrina velutina Willd., Fabaceae, on the root meristem cells of Allium cepa
title_fullStr Genotoxicity and cytotoxicity of Erythrina velutina Willd., Fabaceae, on the root meristem cells of Allium cepa
title_full_unstemmed Genotoxicity and cytotoxicity of Erythrina velutina Willd., Fabaceae, on the root meristem cells of Allium cepa
title_sort Genotoxicity and cytotoxicity of Erythrina velutina Willd., Fabaceae, on the root meristem cells of Allium cepa
author Silva,Déborah S. B. S.
author_facet Silva,Déborah S. B. S.
Garcia,Anuska C. F. S.
Mata,Samuel S.
Oliveira,Betejane de
Estevam,Charles S.
Scher,Ricardo
Pantaleao,Silmara M.
author_role author
author2 Garcia,Anuska C. F. S.
Mata,Samuel S.
Oliveira,Betejane de
Estevam,Charles S.
Scher,Ricardo
Pantaleao,Silmara M.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva,Déborah S. B. S.
Garcia,Anuska C. F. S.
Mata,Samuel S.
Oliveira,Betejane de
Estevam,Charles S.
Scher,Ricardo
Pantaleao,Silmara M.
dc.subject.por.fl_str_mv Erythrina velutina
Allium cepa
root growth
mitotic index
chromosomal aberration
topic Erythrina velutina
Allium cepa
root growth
mitotic index
chromosomal aberration
description The effects of the decoction of Erythrina velutina Willd., Fabaceae, were investigated using the root meristem cells of Allium cepa L., Amaryllidaceae. Ten concentrations of the aqueous extract (0.125 to 1.25%) of this medicinal plant were analyzed at both macroscopic and microscopic levels. All concentrations showed root growth inhibition after 96 h treatment. Although there were no significant differences between the mitotic indexes of any concentration and the control, there were changes in the frequencies of cell stages at three different concentrations. Additionally, the presence of five different cells abnormalities was recorded: chromosome bridging, lagging chromosomes, chromosome fragments, disturbed metaphase and disturbed anaphase. These results suggest inhibitory and genotoxic activity of the decoction of E. velutina on Allium cepa.
publishDate 2011
dc.date.none.fl_str_mv 2011-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000100016
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000100016
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2011005000024
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.21 n.1 2011
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
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reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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