QTL affecting body weight in a candidate region of cattle chromosome 5

Detalhes bibliográficos
Autor(a) principal: Machado,Mariana B.B.
Data de Publicação: 2003
Outros Autores: Alencar,Maurício M., Pereira,Andréa P., Oliveira,Henrique N., Casas,Eduardo, Coutinho,Luis L., Regitano,Luciana C.A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Genetics and Molecular Biology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572003000300008
Resumo: The objective of this work was to identify QTLs for liveweight in a candidate region of bovine chromosome 5. Half-sib families from two lines, one traditional and the other new, of Canchim beef cattle (5/8 Charolais + 3/8 Zebu) were genotyped for four microsatellite markers, including the microsatellite in the IGF-1 (insulin-like growth factor-1) promoter region. Significant differences in allele distribution between the two lines were found for three markers. Interval mapping analyses in this region indicated the presence of a QTL controlling birth weight (p < 0.05) and of a QTL influencing breeding value for yearling weight (p < 0.01) in the newer line of the breed. The previously identified interaction between the IGF-1 genotype and genetic group strengthens the hypothesis of a linked QTL rather than an IGF-1 effect on growth traits in the Canchim cattle.
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spelling QTL affecting body weight in a candidate region of cattle chromosome 5QTLgrowth traitsmicrosatellitebovineThe objective of this work was to identify QTLs for liveweight in a candidate region of bovine chromosome 5. Half-sib families from two lines, one traditional and the other new, of Canchim beef cattle (5/8 Charolais + 3/8 Zebu) were genotyped for four microsatellite markers, including the microsatellite in the IGF-1 (insulin-like growth factor-1) promoter region. Significant differences in allele distribution between the two lines were found for three markers. Interval mapping analyses in this region indicated the presence of a QTL controlling birth weight (p < 0.05) and of a QTL influencing breeding value for yearling weight (p < 0.01) in the newer line of the breed. The previously identified interaction between the IGF-1 genotype and genetic group strengthens the hypothesis of a linked QTL rather than an IGF-1 effect on growth traits in the Canchim cattle.Sociedade Brasileira de Genética2003-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572003000300008Genetics and Molecular Biology v.26 n.3 2003reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47572003000300008info:eu-repo/semantics/openAccessMachado,Mariana B.B.Alencar,Maurício M.Pereira,Andréa P.Oliveira,Henrique N.Casas,EduardoCoutinho,Luis L.Regitano,Luciana C.A.eng2003-09-29T00:00:00Zoai:scielo:S1415-47572003000300008Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2003-09-29T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false
dc.title.none.fl_str_mv QTL affecting body weight in a candidate region of cattle chromosome 5
title QTL affecting body weight in a candidate region of cattle chromosome 5
spellingShingle QTL affecting body weight in a candidate region of cattle chromosome 5
Machado,Mariana B.B.
QTL
growth traits
microsatellite
bovine
title_short QTL affecting body weight in a candidate region of cattle chromosome 5
title_full QTL affecting body weight in a candidate region of cattle chromosome 5
title_fullStr QTL affecting body weight in a candidate region of cattle chromosome 5
title_full_unstemmed QTL affecting body weight in a candidate region of cattle chromosome 5
title_sort QTL affecting body weight in a candidate region of cattle chromosome 5
author Machado,Mariana B.B.
author_facet Machado,Mariana B.B.
Alencar,Maurício M.
Pereira,Andréa P.
Oliveira,Henrique N.
Casas,Eduardo
Coutinho,Luis L.
Regitano,Luciana C.A.
author_role author
author2 Alencar,Maurício M.
Pereira,Andréa P.
Oliveira,Henrique N.
Casas,Eduardo
Coutinho,Luis L.
Regitano,Luciana C.A.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Machado,Mariana B.B.
Alencar,Maurício M.
Pereira,Andréa P.
Oliveira,Henrique N.
Casas,Eduardo
Coutinho,Luis L.
Regitano,Luciana C.A.
dc.subject.por.fl_str_mv QTL
growth traits
microsatellite
bovine
topic QTL
growth traits
microsatellite
bovine
description The objective of this work was to identify QTLs for liveweight in a candidate region of bovine chromosome 5. Half-sib families from two lines, one traditional and the other new, of Canchim beef cattle (5/8 Charolais + 3/8 Zebu) were genotyped for four microsatellite markers, including the microsatellite in the IGF-1 (insulin-like growth factor-1) promoter region. Significant differences in allele distribution between the two lines were found for three markers. Interval mapping analyses in this region indicated the presence of a QTL controlling birth weight (p < 0.05) and of a QTL influencing breeding value for yearling weight (p < 0.01) in the newer line of the breed. The previously identified interaction between the IGF-1 genotype and genetic group strengthens the hypothesis of a linked QTL rather than an IGF-1 effect on growth traits in the Canchim cattle.
publishDate 2003
dc.date.none.fl_str_mv 2003-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572003000300008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572003000300008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1415-47572003000300008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv Genetics and Molecular Biology v.26 n.3 2003
reponame:Genetics and Molecular Biology
instname:Sociedade Brasileira de Genética (SBG)
instacron:SBG
instname_str Sociedade Brasileira de Genética (SBG)
instacron_str SBG
institution SBG
reponame_str Genetics and Molecular Biology
collection Genetics and Molecular Biology
repository.name.fl_str_mv Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)
repository.mail.fl_str_mv ||editor@gmb.org.br
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