Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury

Bibliographic Details
Main Author: Rocha,Carlos Alberto Machado da
Publication Date: 2011
Other Authors: Cunha,Lorena Araújo da, Pinheiro,Raul Henrique da Silva, Bahia,Marcelo de Oliveira, Burbano,Rommel Mario Rodríguez
Format: Article
Language: eng
Source: Genetics and Molecular Biology
Download full: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000400024
Summary: The frequencies of micronuclei (MN) and morphological nuclear abnormalities (NA) in erythrocytes in the peripheral blood of tambaqui (Colossoma macropomum), treated with 2 mg.L-1 methylmercury (MeHg), were analyzed. Two groups (nine specimens in each) were exposed to MeHg for different periods (group A - 24 h; group B - 120 h). A third group served as negative control (group C, untreated; n = 9). Although, when compared to the control group there were no significant differences in MN frequency in the treated groups, for NA, the differences between the frequencies of group B (treated for 120 h) and the control group were extremely significant (p < 0.02), thus demonstrating the potentially adverse effects of MeHg on C. macropomum erythrocytes after prolonged exposure.
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spelling Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercurycytotoxicitygenotoxicitymethylmercurymicronuclei assayThe frequencies of micronuclei (MN) and morphological nuclear abnormalities (NA) in erythrocytes in the peripheral blood of tambaqui (Colossoma macropomum), treated with 2 mg.L-1 methylmercury (MeHg), were analyzed. Two groups (nine specimens in each) were exposed to MeHg for different periods (group A - 24 h; group B - 120 h). A third group served as negative control (group C, untreated; n = 9). Although, when compared to the control group there were no significant differences in MN frequency in the treated groups, for NA, the differences between the frequencies of group B (treated for 120 h) and the control group were extremely significant (p < 0.02), thus demonstrating the potentially adverse effects of MeHg on C. macropomum erythrocytes after prolonged exposure.Sociedade Brasileira de Genética2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000400024Genetics and Molecular Biology v.34 n.4 2011reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47572011000400024info:eu-repo/semantics/openAccessRocha,Carlos Alberto Machado daCunha,Lorena Araújo daPinheiro,Raul Henrique da SilvaBahia,Marcelo de OliveiraBurbano,Rommel Mario Rodríguezeng2011-11-11T00:00:00Zoai:scielo:S1415-47572011000400024Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2011-11-11T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false
dc.title.none.fl_str_mv Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury
title Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury
spellingShingle Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury
Rocha,Carlos Alberto Machado da
cytotoxicity
genotoxicity
methylmercury
micronuclei assay
title_short Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury
title_full Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury
title_fullStr Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury
title_full_unstemmed Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury
title_sort Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury
author Rocha,Carlos Alberto Machado da
author_facet Rocha,Carlos Alberto Machado da
Cunha,Lorena Araújo da
Pinheiro,Raul Henrique da Silva
Bahia,Marcelo de Oliveira
Burbano,Rommel Mario Rodríguez
author_role author
author2 Cunha,Lorena Araújo da
Pinheiro,Raul Henrique da Silva
Bahia,Marcelo de Oliveira
Burbano,Rommel Mario Rodríguez
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Rocha,Carlos Alberto Machado da
Cunha,Lorena Araújo da
Pinheiro,Raul Henrique da Silva
Bahia,Marcelo de Oliveira
Burbano,Rommel Mario Rodríguez
dc.subject.por.fl_str_mv cytotoxicity
genotoxicity
methylmercury
micronuclei assay
topic cytotoxicity
genotoxicity
methylmercury
micronuclei assay
description The frequencies of micronuclei (MN) and morphological nuclear abnormalities (NA) in erythrocytes in the peripheral blood of tambaqui (Colossoma macropomum), treated with 2 mg.L-1 methylmercury (MeHg), were analyzed. Two groups (nine specimens in each) were exposed to MeHg for different periods (group A - 24 h; group B - 120 h). A third group served as negative control (group C, untreated; n = 9). Although, when compared to the control group there were no significant differences in MN frequency in the treated groups, for NA, the differences between the frequencies of group B (treated for 120 h) and the control group were extremely significant (p < 0.02), thus demonstrating the potentially adverse effects of MeHg on C. macropomum erythrocytes after prolonged exposure.
publishDate 2011
dc.date.none.fl_str_mv 2011-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000400024
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000400024
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1415-47572011000400024
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv Genetics and Molecular Biology v.34 n.4 2011
reponame:Genetics and Molecular Biology
instname:Sociedade Brasileira de Genética (SBG)
instacron:SBG
instname_str Sociedade Brasileira de Genética (SBG)
instacron_str SBG
institution SBG
reponame_str Genetics and Molecular Biology
collection Genetics and Molecular Biology
repository.name.fl_str_mv Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)
repository.mail.fl_str_mv ||editor@gmb.org.br
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