Comparison of HMOX1 expression and enzyme activity in blue-shelled chickens and brown-shelled chickens

Detalhes bibliográficos
Autor(a) principal: Wang,ZhePeng
Data de Publicação: 2013
Outros Autores: Liu,RuiFang, Wang,AnRu
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Genetics and Molecular Biology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000200020
Resumo: Blue egg coloring is attributed to biliverdin derived from the oxidative degradation of heme through catalysis by heme oxygenase (HO). The pigment is secreted into the eggshell by the shell gland. There is uncertainty as to whether the pigment is synthesized in the shell gland or in other tissues. To investigate the site of pigment biosynthesis, the expression of heme oxygenase (decycling) 1 (HMOX1), a gene encoding HO, and HO activity in liver and spleen were compared between blue-shelled chickens (n=12) and brown-shelled chickens (n=12). There were no significant differences in HMOX1 expression and HO activity in these tissues between the two groups. Since the liver and spleen, two important sites outside the shell gland where heme is degraded into biliverdin, CO and Fe2+, did not differ in HO expression and activity we conclude that the pigment is most likely synthesized in the shell gland.
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spelling Comparison of HMOX1 expression and enzyme activity in blue-shelled chickens and brown-shelled chickensbiliverdinblue eggchickenHMOX1Blue egg coloring is attributed to biliverdin derived from the oxidative degradation of heme through catalysis by heme oxygenase (HO). The pigment is secreted into the eggshell by the shell gland. There is uncertainty as to whether the pigment is synthesized in the shell gland or in other tissues. To investigate the site of pigment biosynthesis, the expression of heme oxygenase (decycling) 1 (HMOX1), a gene encoding HO, and HO activity in liver and spleen were compared between blue-shelled chickens (n=12) and brown-shelled chickens (n=12). There were no significant differences in HMOX1 expression and HO activity in these tissues between the two groups. Since the liver and spleen, two important sites outside the shell gland where heme is degraded into biliverdin, CO and Fe2+, did not differ in HO expression and activity we conclude that the pigment is most likely synthesized in the shell gland.Sociedade Brasileira de Genética2013-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000200020Genetics and Molecular Biology v.36 n.2 2013reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47572013000200020info:eu-repo/semantics/openAccessWang,ZhePengLiu,RuiFangWang,AnRueng2013-06-07T00:00:00Zoai:scielo:S1415-47572013000200020Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2013-06-07T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false
dc.title.none.fl_str_mv Comparison of HMOX1 expression and enzyme activity in blue-shelled chickens and brown-shelled chickens
title Comparison of HMOX1 expression and enzyme activity in blue-shelled chickens and brown-shelled chickens
spellingShingle Comparison of HMOX1 expression and enzyme activity in blue-shelled chickens and brown-shelled chickens
Wang,ZhePeng
biliverdin
blue egg
chicken
HMOX1
title_short Comparison of HMOX1 expression and enzyme activity in blue-shelled chickens and brown-shelled chickens
title_full Comparison of HMOX1 expression and enzyme activity in blue-shelled chickens and brown-shelled chickens
title_fullStr Comparison of HMOX1 expression and enzyme activity in blue-shelled chickens and brown-shelled chickens
title_full_unstemmed Comparison of HMOX1 expression and enzyme activity in blue-shelled chickens and brown-shelled chickens
title_sort Comparison of HMOX1 expression and enzyme activity in blue-shelled chickens and brown-shelled chickens
author Wang,ZhePeng
author_facet Wang,ZhePeng
Liu,RuiFang
Wang,AnRu
author_role author
author2 Liu,RuiFang
Wang,AnRu
author2_role author
author
dc.contributor.author.fl_str_mv Wang,ZhePeng
Liu,RuiFang
Wang,AnRu
dc.subject.por.fl_str_mv biliverdin
blue egg
chicken
HMOX1
topic biliverdin
blue egg
chicken
HMOX1
description Blue egg coloring is attributed to biliverdin derived from the oxidative degradation of heme through catalysis by heme oxygenase (HO). The pigment is secreted into the eggshell by the shell gland. There is uncertainty as to whether the pigment is synthesized in the shell gland or in other tissues. To investigate the site of pigment biosynthesis, the expression of heme oxygenase (decycling) 1 (HMOX1), a gene encoding HO, and HO activity in liver and spleen were compared between blue-shelled chickens (n=12) and brown-shelled chickens (n=12). There were no significant differences in HMOX1 expression and HO activity in these tissues between the two groups. Since the liver and spleen, two important sites outside the shell gland where heme is degraded into biliverdin, CO and Fe2+, did not differ in HO expression and activity we conclude that the pigment is most likely synthesized in the shell gland.
publishDate 2013
dc.date.none.fl_str_mv 2013-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000200020
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000200020
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1415-47572013000200020
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv Genetics and Molecular Biology v.36 n.2 2013
reponame:Genetics and Molecular Biology
instname:Sociedade Brasileira de Genética (SBG)
instacron:SBG
instname_str Sociedade Brasileira de Genética (SBG)
instacron_str SBG
institution SBG
reponame_str Genetics and Molecular Biology
collection Genetics and Molecular Biology
repository.name.fl_str_mv Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)
repository.mail.fl_str_mv ||editor@gmb.org.br
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