Genetic characterization of the population of São Luís, MA, Brazil

Detalhes bibliográficos
Autor(a) principal: Ferreira,Francileide Lisboa
Data de Publicação: 2005
Outros Autores: Leal-Mesquita,Emygdia Rosa, Santos,Sidney Emanuel Batista dos, Ribeiro-dos-Santos,Ândrea Kely Campos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Genetics and Molecular Biology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000100004
Resumo: Five loci (vWA1, F13A1, D12S67, Apo-B and D1S80) were investigated by polyacrylamide gel electrophoresis followed by silver staining in a sample of 177 individuals from the population of São Luís, State of Maranhão, Brazil. A total of 70 different alleles were identified. A statistically significant deviation from the Hardy-Weinberg equilibrium was observed in a single locus (F13A1, p = 0.0075). The average heterozygosity (H) was estimated at 77.7%, the mean number of alleles per locus as 14. The PD (capacity of genotype differentiation at each locus) ranged from 88.9% (vWA1) to 96.7% (F13A1). The combined PE (power of exclusion) of these five loci was 99.8%. In terms of racial admixture (42% European, 39% Indian, and 19% African Black ancestry), São Luís presented an estimate similar to Belém, another trihybrid Amazonian population.
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spelling Genetic characterization of the population of São Luís, MA, BrazilAmazon regionDNApolymorphismsVNTRsSTRsinterethnic admixtureFive loci (vWA1, F13A1, D12S67, Apo-B and D1S80) were investigated by polyacrylamide gel electrophoresis followed by silver staining in a sample of 177 individuals from the population of São Luís, State of Maranhão, Brazil. A total of 70 different alleles were identified. A statistically significant deviation from the Hardy-Weinberg equilibrium was observed in a single locus (F13A1, p = 0.0075). The average heterozygosity (H) was estimated at 77.7%, the mean number of alleles per locus as 14. The PD (capacity of genotype differentiation at each locus) ranged from 88.9% (vWA1) to 96.7% (F13A1). The combined PE (power of exclusion) of these five loci was 99.8%. In terms of racial admixture (42% European, 39% Indian, and 19% African Black ancestry), São Luís presented an estimate similar to Belém, another trihybrid Amazonian population.Sociedade Brasileira de Genética2005-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000100004Genetics and Molecular Biology v.28 n.1 2005reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47572005000100004info:eu-repo/semantics/openAccessFerreira,Francileide LisboaLeal-Mesquita,Emygdia RosaSantos,Sidney Emanuel Batista dosRibeiro-dos-Santos,Ândrea Kely Camposeng2005-09-08T00:00:00Zoai:scielo:S1415-47572005000100004Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2005-09-08T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false
dc.title.none.fl_str_mv Genetic characterization of the population of São Luís, MA, Brazil
title Genetic characterization of the population of São Luís, MA, Brazil
spellingShingle Genetic characterization of the population of São Luís, MA, Brazil
Ferreira,Francileide Lisboa
Amazon region
DNA
polymorphisms
VNTRs
STRs
interethnic admixture
title_short Genetic characterization of the population of São Luís, MA, Brazil
title_full Genetic characterization of the population of São Luís, MA, Brazil
title_fullStr Genetic characterization of the population of São Luís, MA, Brazil
title_full_unstemmed Genetic characterization of the population of São Luís, MA, Brazil
title_sort Genetic characterization of the population of São Luís, MA, Brazil
author Ferreira,Francileide Lisboa
author_facet Ferreira,Francileide Lisboa
Leal-Mesquita,Emygdia Rosa
Santos,Sidney Emanuel Batista dos
Ribeiro-dos-Santos,Ândrea Kely Campos
author_role author
author2 Leal-Mesquita,Emygdia Rosa
Santos,Sidney Emanuel Batista dos
Ribeiro-dos-Santos,Ândrea Kely Campos
author2_role author
author
author
dc.contributor.author.fl_str_mv Ferreira,Francileide Lisboa
Leal-Mesquita,Emygdia Rosa
Santos,Sidney Emanuel Batista dos
Ribeiro-dos-Santos,Ândrea Kely Campos
dc.subject.por.fl_str_mv Amazon region
DNA
polymorphisms
VNTRs
STRs
interethnic admixture
topic Amazon region
DNA
polymorphisms
VNTRs
STRs
interethnic admixture
description Five loci (vWA1, F13A1, D12S67, Apo-B and D1S80) were investigated by polyacrylamide gel electrophoresis followed by silver staining in a sample of 177 individuals from the population of São Luís, State of Maranhão, Brazil. A total of 70 different alleles were identified. A statistically significant deviation from the Hardy-Weinberg equilibrium was observed in a single locus (F13A1, p = 0.0075). The average heterozygosity (H) was estimated at 77.7%, the mean number of alleles per locus as 14. The PD (capacity of genotype differentiation at each locus) ranged from 88.9% (vWA1) to 96.7% (F13A1). The combined PE (power of exclusion) of these five loci was 99.8%. In terms of racial admixture (42% European, 39% Indian, and 19% African Black ancestry), São Luís presented an estimate similar to Belém, another trihybrid Amazonian population.
publishDate 2005
dc.date.none.fl_str_mv 2005-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000100004
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000100004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1415-47572005000100004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv Genetics and Molecular Biology v.28 n.1 2005
reponame:Genetics and Molecular Biology
instname:Sociedade Brasileira de Genética (SBG)
instacron:SBG
instname_str Sociedade Brasileira de Genética (SBG)
instacron_str SBG
institution SBG
reponame_str Genetics and Molecular Biology
collection Genetics and Molecular Biology
repository.name.fl_str_mv Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)
repository.mail.fl_str_mv ||editor@gmb.org.br
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