Maternal age and Down syndrome in Southeastern Brazil
Autor(a) principal: | |
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Data de Publicação: | 1996 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Genetics |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-84551996000400020 |
Resumo: | The proportion of maternal-age-independent patients estimated among 200 Brazilian Down syndrome children (59.6%) was significantly larger than that of maternal-age-dependent cases (40.4%). The latter proportion is the smallest observed in pertinent literature and due basically to the low mean maternal age of the population analyzed. Based on the remarkable correlation (r = 0.95) between the proportion of maternal-age-dependent patients and the mean maternal age of the general population, a simple predictive equation to estimate the proportion of maternal-age-dependent Down syndrome patients based on the mean maternal age of the general population is suggested in situations where reliable data on the incidence of this syndrome according to maternal age is not available. |
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Brazilian Journal of Genetics |
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Maternal age and Down syndrome in Southeastern Brazilmaternal ageDown syndromeSoutheastern BrazilThe proportion of maternal-age-independent patients estimated among 200 Brazilian Down syndrome children (59.6%) was significantly larger than that of maternal-age-dependent cases (40.4%). The latter proportion is the smallest observed in pertinent literature and due basically to the low mean maternal age of the population analyzed. Based on the remarkable correlation (r = 0.95) between the proportion of maternal-age-dependent patients and the mean maternal age of the general population, a simple predictive equation to estimate the proportion of maternal-age-dependent Down syndrome patients based on the mean maternal age of the general population is suggested in situations where reliable data on the incidence of this syndrome according to maternal age is not available.Sociedade Brasileira de Genética1996-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-84551996000400020Brazilian Journal of Genetics v.19 n.4 1996reponame:Brazilian Journal of Geneticsinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S0100-84551996000400020info:eu-repo/semantics/openAccessBeiguelman,BernardoKrieger,HenriqueSilva,Luciana Marques daeng2006-10-27T00:00:00Zoai:scielo:S0100-84551996000400020Revistahttps://www.gmb.org.br/brazilian-journal-of-geneticsONGhttps://old.scielo.br/oai/scielo-oai.phpsede@sgb.org.br || sede@sgb.org.br0100-84550100-8455opendoar:2006-10-27T00:00Brazilian Journal of Genetics - Sociedade Brasileira de Genética (SBG)false |
dc.title.none.fl_str_mv |
Maternal age and Down syndrome in Southeastern Brazil |
title |
Maternal age and Down syndrome in Southeastern Brazil |
spellingShingle |
Maternal age and Down syndrome in Southeastern Brazil Beiguelman,Bernardo maternal age Down syndrome Southeastern Brazil |
title_short |
Maternal age and Down syndrome in Southeastern Brazil |
title_full |
Maternal age and Down syndrome in Southeastern Brazil |
title_fullStr |
Maternal age and Down syndrome in Southeastern Brazil |
title_full_unstemmed |
Maternal age and Down syndrome in Southeastern Brazil |
title_sort |
Maternal age and Down syndrome in Southeastern Brazil |
author |
Beiguelman,Bernardo |
author_facet |
Beiguelman,Bernardo Krieger,Henrique Silva,Luciana Marques da |
author_role |
author |
author2 |
Krieger,Henrique Silva,Luciana Marques da |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Beiguelman,Bernardo Krieger,Henrique Silva,Luciana Marques da |
dc.subject.por.fl_str_mv |
maternal age Down syndrome Southeastern Brazil |
topic |
maternal age Down syndrome Southeastern Brazil |
description |
The proportion of maternal-age-independent patients estimated among 200 Brazilian Down syndrome children (59.6%) was significantly larger than that of maternal-age-dependent cases (40.4%). The latter proportion is the smallest observed in pertinent literature and due basically to the low mean maternal age of the population analyzed. Based on the remarkable correlation (r = 0.95) between the proportion of maternal-age-dependent patients and the mean maternal age of the general population, a simple predictive equation to estimate the proportion of maternal-age-dependent Down syndrome patients based on the mean maternal age of the general population is suggested in situations where reliable data on the incidence of this syndrome according to maternal age is not available. |
publishDate |
1996 |
dc.date.none.fl_str_mv |
1996-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-84551996000400020 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-84551996000400020 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0100-84551996000400020 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Genética |
publisher.none.fl_str_mv |
Sociedade Brasileira de Genética |
dc.source.none.fl_str_mv |
Brazilian Journal of Genetics v.19 n.4 1996 reponame:Brazilian Journal of Genetics instname:Sociedade Brasileira de Genética (SBG) instacron:SBG |
instname_str |
Sociedade Brasileira de Genética (SBG) |
instacron_str |
SBG |
institution |
SBG |
reponame_str |
Brazilian Journal of Genetics |
collection |
Brazilian Journal of Genetics |
repository.name.fl_str_mv |
Brazilian Journal of Genetics - Sociedade Brasileira de Genética (SBG) |
repository.mail.fl_str_mv |
sede@sgb.org.br || sede@sgb.org.br |
_version_ |
1754734879202869248 |