Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies

Detalhes bibliográficos
Autor(a) principal: Lemes,Raquel M.L.
Data de Publicação: 2010
Outros Autores: Lyon,Juliana P., Moreira,Leonardo M., Resende,Maria Aparecida de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Microbiology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000200008
Resumo: The aim of the present study was to evaluate the antifungal susceptibility profile of Trichosporon species isolated from different sources employing the Clinical and Laboratory Standards Institute (CLSI) method and E-test method. Thirty-four isolates of Trichosporon spp. and six CBS reference samples were tested for their susceptibility to Amphotericin B, 5-flucytosine, Fluconazole, Itraconazole, Voriconazole and Terbinafine. All species showed high Minimun Inhibitory Concentrations (MIC) for Itraconazole and susceptibility to Fluconazole, The comparison among the results obtained by the CLSI method and E-test revealed larger discrepancies among 5-flucytosine and Itraconazole. The present work provides epidemiological data that could influence therapeutic choices. Furthermore, the comparison between different methodologies could help to analyze results obtained by different laboratories.
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spelling Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologiesTrichosporon sppantifungal drugsCLSIE-testThe aim of the present study was to evaluate the antifungal susceptibility profile of Trichosporon species isolated from different sources employing the Clinical and Laboratory Standards Institute (CLSI) method and E-test method. Thirty-four isolates of Trichosporon spp. and six CBS reference samples were tested for their susceptibility to Amphotericin B, 5-flucytosine, Fluconazole, Itraconazole, Voriconazole and Terbinafine. All species showed high Minimun Inhibitory Concentrations (MIC) for Itraconazole and susceptibility to Fluconazole, The comparison among the results obtained by the CLSI method and E-test revealed larger discrepancies among 5-flucytosine and Itraconazole. The present work provides epidemiological data that could influence therapeutic choices. Furthermore, the comparison between different methodologies could help to analyze results obtained by different laboratories.Sociedade Brasileira de Microbiologia2010-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000200008Brazilian Journal of Microbiology v.41 n.2 2010reponame:Brazilian Journal of Microbiologyinstname:Sociedade Brasileira de Microbiologia (SBM)instacron:SBM10.1590/S1517-83822010000200008info:eu-repo/semantics/openAccessLemes,Raquel M.L.Lyon,Juliana P.Moreira,Leonardo M.Resende,Maria Aparecida deeng2010-04-16T00:00:00Zoai:scielo:S1517-83822010000200008Revistahttps://www.scielo.br/j/bjm/ONGhttps://old.scielo.br/oai/scielo-oai.phpbjm@sbmicrobiologia.org.br||mbmartin@usp.br1678-44051517-8382opendoar:2010-04-16T00:00Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)false
dc.title.none.fl_str_mv Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies
title Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies
spellingShingle Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies
Lemes,Raquel M.L.
Trichosporon spp
antifungal drugs
CLSI
E-test
title_short Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies
title_full Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies
title_fullStr Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies
title_full_unstemmed Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies
title_sort Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies
author Lemes,Raquel M.L.
author_facet Lemes,Raquel M.L.
Lyon,Juliana P.
Moreira,Leonardo M.
Resende,Maria Aparecida de
author_role author
author2 Lyon,Juliana P.
Moreira,Leonardo M.
Resende,Maria Aparecida de
author2_role author
author
author
dc.contributor.author.fl_str_mv Lemes,Raquel M.L.
Lyon,Juliana P.
Moreira,Leonardo M.
Resende,Maria Aparecida de
dc.subject.por.fl_str_mv Trichosporon spp
antifungal drugs
CLSI
E-test
topic Trichosporon spp
antifungal drugs
CLSI
E-test
description The aim of the present study was to evaluate the antifungal susceptibility profile of Trichosporon species isolated from different sources employing the Clinical and Laboratory Standards Institute (CLSI) method and E-test method. Thirty-four isolates of Trichosporon spp. and six CBS reference samples were tested for their susceptibility to Amphotericin B, 5-flucytosine, Fluconazole, Itraconazole, Voriconazole and Terbinafine. All species showed high Minimun Inhibitory Concentrations (MIC) for Itraconazole and susceptibility to Fluconazole, The comparison among the results obtained by the CLSI method and E-test revealed larger discrepancies among 5-flucytosine and Itraconazole. The present work provides epidemiological data that could influence therapeutic choices. Furthermore, the comparison between different methodologies could help to analyze results obtained by different laboratories.
publishDate 2010
dc.date.none.fl_str_mv 2010-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000200008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000200008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1517-83822010000200008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Microbiologia
publisher.none.fl_str_mv Sociedade Brasileira de Microbiologia
dc.source.none.fl_str_mv Brazilian Journal of Microbiology v.41 n.2 2010
reponame:Brazilian Journal of Microbiology
instname:Sociedade Brasileira de Microbiologia (SBM)
instacron:SBM
instname_str Sociedade Brasileira de Microbiologia (SBM)
instacron_str SBM
institution SBM
reponame_str Brazilian Journal of Microbiology
collection Brazilian Journal of Microbiology
repository.name.fl_str_mv Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)
repository.mail.fl_str_mv bjm@sbmicrobiologia.org.br||mbmartin@usp.br
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