Susceptibility to amphotericin B of Candida spp. strains isolated in Ceará, Northeastern Brazil

Detalhes bibliográficos
Autor(a) principal: Silva,Cecília Rocha da
Data de Publicação: 2013
Outros Autores: Magalhães,Hemerson Iury Ferreira, Moraes,Manoel Odorico de, Nobre Júnior,Hélio Vitoriano
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000200244
Resumo: IntroductionAmphotericin B (AMB) is an antifungal agent used extensively in clinical medicine, yet resistance remains low. This study aims to evaluate the susceptibility of Candida spp. against AMB.MethodsFor broth microdilution susceptibility testing, 77 strains of Candida spp. were selected (32 C. albicans, 33 C. tropicalis, and 12 C. parapsilosis). The strains were considered susceptible when they exhibited MIC≤1.0µg/ml.ResultsNone of the strains showed an MIC greater than 0.25µg/ml.ConclusionsFurther works are necessary, with a higher number of strains, to assess the validity of the results used in this study.
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spelling Susceptibility to amphotericin B of Candida spp. strains isolated in Ceará, Northeastern BrazilAmphotericin BCandida sppProtocol M27-A3IntroductionAmphotericin B (AMB) is an antifungal agent used extensively in clinical medicine, yet resistance remains low. This study aims to evaluate the susceptibility of Candida spp. against AMB.MethodsFor broth microdilution susceptibility testing, 77 strains of Candida spp. were selected (32 C. albicans, 33 C. tropicalis, and 12 C. parapsilosis). The strains were considered susceptible when they exhibited MIC≤1.0µg/ml.ResultsNone of the strains showed an MIC greater than 0.25µg/ml.ConclusionsFurther works are necessary, with a higher number of strains, to assess the validity of the results used in this study.Sociedade Brasileira de Medicina Tropical - SBMT2013-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000200244Revista da Sociedade Brasileira de Medicina Tropical v.46 n.2 2013reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/0037-8682-1060-2013info:eu-repo/semantics/openAccessSilva,Cecília Rocha daMagalhães,Hemerson Iury FerreiraMoraes,Manoel Odorico deNobre Júnior,Hélio Vitorianoeng2015-10-27T00:00:00Zoai:scielo:S0037-86822013000200244Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2015-10-27T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false
dc.title.none.fl_str_mv Susceptibility to amphotericin B of Candida spp. strains isolated in Ceará, Northeastern Brazil
title Susceptibility to amphotericin B of Candida spp. strains isolated in Ceará, Northeastern Brazil
spellingShingle Susceptibility to amphotericin B of Candida spp. strains isolated in Ceará, Northeastern Brazil
Silva,Cecília Rocha da
Amphotericin B
Candida spp
Protocol M27-A3
title_short Susceptibility to amphotericin B of Candida spp. strains isolated in Ceará, Northeastern Brazil
title_full Susceptibility to amphotericin B of Candida spp. strains isolated in Ceará, Northeastern Brazil
title_fullStr Susceptibility to amphotericin B of Candida spp. strains isolated in Ceará, Northeastern Brazil
title_full_unstemmed Susceptibility to amphotericin B of Candida spp. strains isolated in Ceará, Northeastern Brazil
title_sort Susceptibility to amphotericin B of Candida spp. strains isolated in Ceará, Northeastern Brazil
author Silva,Cecília Rocha da
author_facet Silva,Cecília Rocha da
Magalhães,Hemerson Iury Ferreira
Moraes,Manoel Odorico de
Nobre Júnior,Hélio Vitoriano
author_role author
author2 Magalhães,Hemerson Iury Ferreira
Moraes,Manoel Odorico de
Nobre Júnior,Hélio Vitoriano
author2_role author
author
author
dc.contributor.author.fl_str_mv Silva,Cecília Rocha da
Magalhães,Hemerson Iury Ferreira
Moraes,Manoel Odorico de
Nobre Júnior,Hélio Vitoriano
dc.subject.por.fl_str_mv Amphotericin B
Candida spp
Protocol M27-A3
topic Amphotericin B
Candida spp
Protocol M27-A3
description IntroductionAmphotericin B (AMB) is an antifungal agent used extensively in clinical medicine, yet resistance remains low. This study aims to evaluate the susceptibility of Candida spp. against AMB.MethodsFor broth microdilution susceptibility testing, 77 strains of Candida spp. were selected (32 C. albicans, 33 C. tropicalis, and 12 C. parapsilosis). The strains were considered susceptible when they exhibited MIC≤1.0µg/ml.ResultsNone of the strains showed an MIC greater than 0.25µg/ml.ConclusionsFurther works are necessary, with a higher number of strains, to assess the validity of the results used in this study.
publishDate 2013
dc.date.none.fl_str_mv 2013-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000200244
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0037-8682-1060-2013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical v.46 n.2 2013
reponame:Revista da Sociedade Brasileira de Medicina Tropical
instname:Sociedade Brasileira de Medicina Tropical (SBMT)
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instacron_str SBMT
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collection Revista da Sociedade Brasileira de Medicina Tropical
repository.name.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)
repository.mail.fl_str_mv ||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br
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