Efficacy of oral sarolaner for the treatment of generalized demodicosis in dogs

Detalhes bibliográficos
Autor(a) principal: Goulart Carvalho, Flavia Clare
Data de Publicação: 2019
Outros Autores: Lopes, Natália Lôres, Machado, Marília Alves, Merlo, Alexandre, Fernandes, Julio Israel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Veterinary Medicine
Texto Completo: https://rbmv.org/BJVM/article/view/1022
Resumo: The aim of this study was to report the treatment efficacy of generalized demodicosis with oral sarolaner in dogs. Twenty-seven dogs diagnosed with generalized demodicosis were treated with oral sarolanerat a dose of 2.0 mg/kg every 30 days. Sarolaner was administered on days 0, 30, 60, and 90. The dogs were analyzed as positive or negative for demodicosis. Clinical parameters were recorded before and after treatment every 30 days for 90 days. On day 30, 77.7% of the dogs exhibited negative results for demodicosis in skin scrapings, and on day +60, 100% of dogs showed negative results on parasitological examination, which continued until day 90. On day 30, 7.41% of the dogs showed clinical remission, followed by 74.07% on day +60. On day +90, 88.88% of the dogs showed complete clinical recovery. Sarolaner was effective in treating canine generalized demodicosis and could be an excellent alternative to conventional treatment, especially for animals in whom ivermectin is contraindicated.
id SBMV-1_7ab381b0be6e8d8674d0227f07f495b5
oai_identifier_str oai:ojs.rbmv.org:article/1022
network_acronym_str SBMV-1
network_name_str Brazilian Journal of Veterinary Medicine
repository_id_str
spelling Efficacy of oral sarolaner for the treatment of generalized demodicosis in dogsEficácia do sarolaner oral no tratamento da demodiciose canina generalizadaCãesEficáciaIsoxazolinasDemodex canisDogsEfficacyIsoxazolinesDemodex canisThe aim of this study was to report the treatment efficacy of generalized demodicosis with oral sarolaner in dogs. Twenty-seven dogs diagnosed with generalized demodicosis were treated with oral sarolanerat a dose of 2.0 mg/kg every 30 days. Sarolaner was administered on days 0, 30, 60, and 90. The dogs were analyzed as positive or negative for demodicosis. Clinical parameters were recorded before and after treatment every 30 days for 90 days. On day 30, 77.7% of the dogs exhibited negative results for demodicosis in skin scrapings, and on day +60, 100% of dogs showed negative results on parasitological examination, which continued until day 90. On day 30, 7.41% of the dogs showed clinical remission, followed by 74.07% on day +60. On day +90, 88.88% of the dogs showed complete clinical recovery. Sarolaner was effective in treating canine generalized demodicosis and could be an excellent alternative to conventional treatment, especially for animals in whom ivermectin is contraindicated.O objetivo deste estudo foi relatar a eficácia do tratamento da demodicose generalizada canina com sarolaner oral em cães. Vinte e sete cães diagnosticados com demodicose generalizada através de descamação profunda da pele foram tratados com sarolaner oral na dose de 2,0 mg / kg a cada 30 dias. As raspagens profundas da pele foram realizadas nos dias 0, +30, +60 e +90 e analisadas como positivas ou negativas. Os principais sinais clínicos (pápulas, máculas, pústulas, escamas ou crostas, eritema, comedões e alopécia), assim como lesões dermatológicas foram registradas antes e durante o tratamento a cada 30 dias. No dia +30, 77,7% dos cães obtiveram raspado cutâneo negativo, no dia +60, 100% já eram negativos ao exame parasitológico e permaneceram até o dia 90. Em relação à cura clínica, 7,41% apresentaram cura clínica no dia +30, seguido de 74,07% no dia +60. No dia +90, 88,88% dos cães apresentaram recuperação completa dos sinais clínicos. O Sarolaner foi eficaz no tratamento da demodicose generalizada canina e pode ser uma ótima alternativa para os tratamentos convencionais, principalmente para os animais com contra-indicações.Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.2019-09-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionpeer reviewedAvaliado pelos paresapplication/pdfhttps://rbmv.org/BJVM/article/view/102210.29374/bjvm.102219Brazilian Journal of Veterinary Medicine; Vol. 41 No. 1 (2019); e102219Revista Brasileira de Medicina Veterinária; v. 41 n. 1 (2019); e1022192527-21790100-2430reponame:Brazilian Journal of Veterinary Medicineinstname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)instacron:SBMVenghttps://rbmv.org/BJVM/article/view/1022/963Copyright (c) 2019 Flavia Clare Goulart Carvalho, Natália Lôres Lopes, Marília Alves Machado, Alexandre Merlo, Julio Israel Fernandesinfo:eu-repo/semantics/openAccessGoulart Carvalho, Flavia Clare Lopes, Natália LôresMachado, Marília AlvesMerlo, AlexandreFernandes, Julio Israel2020-12-23T17:24:50Zoai:ojs.rbmv.org:article/1022Revistahttps://rbmv.org/BJVMONGhttps://rbmv.org/BJVM/oaicontato.rbmv@gmail.com2527-21790100-2430opendoar:2020-12-23T17:24:50Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)false
dc.title.none.fl_str_mv Efficacy of oral sarolaner for the treatment of generalized demodicosis in dogs
Eficácia do sarolaner oral no tratamento da demodiciose canina generalizada
title Efficacy of oral sarolaner for the treatment of generalized demodicosis in dogs
spellingShingle Efficacy of oral sarolaner for the treatment of generalized demodicosis in dogs
Goulart Carvalho, Flavia Clare
Cães
Eficácia
Isoxazolinas
Demodex canis
Dogs
Efficacy
Isoxazolines
Demodex canis
title_short Efficacy of oral sarolaner for the treatment of generalized demodicosis in dogs
title_full Efficacy of oral sarolaner for the treatment of generalized demodicosis in dogs
title_fullStr Efficacy of oral sarolaner for the treatment of generalized demodicosis in dogs
title_full_unstemmed Efficacy of oral sarolaner for the treatment of generalized demodicosis in dogs
title_sort Efficacy of oral sarolaner for the treatment of generalized demodicosis in dogs
author Goulart Carvalho, Flavia Clare
author_facet Goulart Carvalho, Flavia Clare
Lopes, Natália Lôres
Machado, Marília Alves
Merlo, Alexandre
Fernandes, Julio Israel
author_role author
author2 Lopes, Natália Lôres
Machado, Marília Alves
Merlo, Alexandre
Fernandes, Julio Israel
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Goulart Carvalho, Flavia Clare
Lopes, Natália Lôres
Machado, Marília Alves
Merlo, Alexandre
Fernandes, Julio Israel
dc.subject.por.fl_str_mv Cães
Eficácia
Isoxazolinas
Demodex canis
Dogs
Efficacy
Isoxazolines
Demodex canis
topic Cães
Eficácia
Isoxazolinas
Demodex canis
Dogs
Efficacy
Isoxazolines
Demodex canis
description The aim of this study was to report the treatment efficacy of generalized demodicosis with oral sarolaner in dogs. Twenty-seven dogs diagnosed with generalized demodicosis were treated with oral sarolanerat a dose of 2.0 mg/kg every 30 days. Sarolaner was administered on days 0, 30, 60, and 90. The dogs were analyzed as positive or negative for demodicosis. Clinical parameters were recorded before and after treatment every 30 days for 90 days. On day 30, 77.7% of the dogs exhibited negative results for demodicosis in skin scrapings, and on day +60, 100% of dogs showed negative results on parasitological examination, which continued until day 90. On day 30, 7.41% of the dogs showed clinical remission, followed by 74.07% on day +60. On day +90, 88.88% of the dogs showed complete clinical recovery. Sarolaner was effective in treating canine generalized demodicosis and could be an excellent alternative to conventional treatment, especially for animals in whom ivermectin is contraindicated.
publishDate 2019
dc.date.none.fl_str_mv 2019-09-27
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
peer reviewed
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbmv.org/BJVM/article/view/1022
10.29374/bjvm.102219
url https://rbmv.org/BJVM/article/view/1022
identifier_str_mv 10.29374/bjvm.102219
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rbmv.org/BJVM/article/view/1022/963
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.
publisher.none.fl_str_mv Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.
dc.source.none.fl_str_mv Brazilian Journal of Veterinary Medicine; Vol. 41 No. 1 (2019); e102219
Revista Brasileira de Medicina Veterinária; v. 41 n. 1 (2019); e102219
2527-2179
0100-2430
reponame:Brazilian Journal of Veterinary Medicine
instname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)
instacron:SBMV
instname_str Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)
instacron_str SBMV
institution SBMV
reponame_str Brazilian Journal of Veterinary Medicine
collection Brazilian Journal of Veterinary Medicine
repository.name.fl_str_mv Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)
repository.mail.fl_str_mv contato.rbmv@gmail.com
_version_ 1754638969844269056

Registros relacionados